Pengfan Zhang Profile
Pengfan Zhang

@alvinpf1

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Postdoc at Spencer Diamond's lab @igisci. Former PhD from Ruben Garrido-Oter's group @MPIPZ, working on microbiome data analysis. RT≠Endorsement

Berkeley, CA
Joined May 2019
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@alvinpf1
Pengfan Zhang
1 year
RT @biorxiv_micrbio: Probing the eukaryotic microbes of ruminants with a deep-learning classifier and comprehensive protein databases http….
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@alvinpf1
Pengfan Zhang
1 year
6) In this work we also characterize the impacts of red seaweed supplementation on microbiome carbohydrate catabolism and VFA biosynthesis. To conclude this thread, we are a group of audacious folks with the ambition to mitigate climate change through rumen microbiome modeling.
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@alvinpf1
Pengfan Zhang
1 year
5) But why does this Duodenibacillus Sp. outcompete other 8 the NiFe_1d encoding hydrogenotrophic organisms we identified? Comparative genomic analysis also showed that Duodenibacillus Sp. possesses additional specialized functions that support the anerobic respiration of.
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@alvinpf1
Pengfan Zhang
1 year
4) By comparing the encoded metabolic potential of the Duodenibacillus Sp. genome to the other 8 NiFe_1d hydrogenase expressing organisms in our samples we found that the Duodenibacillus Sp. exclusively could couple the oxidation of H2 to the reduction of fumarate to succinate,.
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@alvinpf1
Pengfan Zhang
1 year
3) H2 serves as an electron donor for methanogenesis and suppression of methanogenesis is coupled to elevated H2 partial pressure in the rumen. Correspondingly, we found the up-regulation of H2-consuming NiFe_1d hydrogenases when methane production is suppressed. Furthermore, we
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@alvinpf1
Pengfan Zhang
1 year
2) We found that red seaweed treatment caused a decrease in both archaeal abundance and their corresponding methanogenesis activities. We found both hydrogenotrophic and methylotrophic methanogenesis were suppressed at the transcriptional level.
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@alvinpf1
Pengfan Zhang
1 year
1) Enteric methane emission from livestock accounts for ~30% of anthropogenic methane emissions. Using red seaweed as a feed supplement in cows can reduce methane emissions by >50% without compromising feed efficiency and productivity. Methane production is mediated by
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@alvinpf1
Pengfan Zhang
1 year
Excited to share this amazing work led by @TheHessLab and @Dr__Diamond at @igisci and sponsored by @TheAudaciousPrj. We use multi-omics to show how the rumen microbiome responds to methanogenesis suppression and identify a Duodenibacillus Sp. as an alternative hydrogen sink.
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@alvinpf1
Pengfan Zhang
1 year
RT @Dr__Diamond: The #microbiome of the cow rumen produces ~30 % of anthropogenic #methane, but how does this microbiome change when methan….
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@alvinpf1
Pengfan Zhang
1 year
RT @KaWaiMa6: Please RT‼️ We are hiring @IPMBSinica. Are you interested in plant-microbiota interaction? We are looking for a RA/postdoc wo….
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@alvinpf1
Pengfan Zhang
2 years
I would like to thank all of you for showing up in my farewell party to celebrate and memorize the amazing and fruitful journey I had @mpipz_cologne. Tomorrow I will fly to the USA to start my postdoc @Dr__Diamond's lab @igisci. Another exciting cruise is ready to start.
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@alvinpf1
Pengfan Zhang
2 years
RT @Dr__Diamond: 🚨MY LAB IS STILL HIRING🚨 .Want to work @igisci as part of @TheAudaciousPrj. More Info:
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@alvinpf1
Pengfan Zhang
2 years
RT @Dr__Diamond: 🚨MY LAB IS HIRING🚨 .Want to work @igisci as part of @TheAudaciousPrj. We are looking for postdocs with experience in micro….
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@alvinpf1
Pengfan Zhang
2 years
Which probability is higher: win one million lottery prize or design a random barcode sequence(12bp) exactly matches the sequencing primer used by a sequencing company?.Now the thing is all the reads from that sample don't have corresponding barcode sequences.
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@alvinpf1
Pengfan Zhang
2 years
Finally successfully defended my Phd. I would like to thank everyone for joining my defense and helping me over the course of my PhD, especially Ruben Garrido-Other. My colleagues are really amazing craftsmen and this hat is a very special and sweet gift for the Valentine's Day
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@alvinpf1
Pengfan Zhang
3 years
Big congrats to Ruben for being awarded the ERC starting grant.
@ERC_Research
European Research Council (ERC)
3 years
📢 The ERC's 2022 Starting Grant competition results are now revealed. Over €636 million to fund the best ideas of younger scientists. Find out who, where and why 👉 . 🇪🇺#EUfunded @HorizonEU #FrontierResearch #ERCStG
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@alvinpf1
Pengfan Zhang
3 years
If you are still struggling with Circos plot, try this new easy-to-use software out in I meta.
@iMetaScience
iMeta
3 years
A painless way to customize Circos plot: From data preparation to visualization using TBtools @wileymicrobio
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@alvinpf1
Pengfan Zhang
4 years
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@alvinpf1
Pengfan Zhang
4 years
Finally my baby finds it's home @ISMEComms. Thank everyone for their great contributions to this project.
@alvinpf1
Pengfan Zhang
4 years
1/3 The first manuscript during my PhD is online. Thanks all the authors for your contributions to this work!.In this paper, we developed an algorithm (Rbec, will be available for downloading shortly) for accurately profile microbial communities in synthetic communities.
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@alvinpf1
Pengfan Zhang
4 years
RT @kathywippel: Our paper is now out in @NatureMicrobiol ! We show that there’s host preference among bacterial communities colonizing pla….
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