Alexandre P. Magalhães
@alexpmagalhaes
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Computational biologist and bioinformatics with a pinch of wet lab. Mostly I fix stuff.
/usr/local/bin
Joined August 2014
Check out our new paper on suboptimality of human TFs activity and specificity. A trade off that is encoded in aromatic dispersion in IDR. Big thanks to @dhnisz for mentorship and specially my partner in crime @Naderij_ and of course all other contributors.
Human TFs face a molecular trade-off between activity and specificity encoded as submaximal dispersion of aromatic residues in their disordered regions. A collaborative effort of @dhnisz, @VingronLab and Graf Lab published today in @NatureCellBio
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RT @YZhang1997: What controls condensate composition and function beyond binding stoichiometry? We show that condensate microenvironments p….
nature.com
Nature - Targeting a non-natural micropeptide ‘killswitch’ to several biomolecular condensates altered condensate compositions and revealed condensate functions in human cells
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RT @Nature: Nature research paper: Probing condensate microenvironments with a micropeptide killswitch.
nature.com
Nature - Targeting a non-natural micropeptide ‘killswitch’ to several biomolecular condensates altered condensate compositions and revealed condensate functions in human cells
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RT @henri_niskanen: Check out a technology feature in @Nature by @ElieDolgin regarding our recent 'Killswitch' publication .
nature.com
Nature - Synthetic peptide fixes biomolecular condensates, revealing how these enigmatic cell structures actually work.
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RT @dhnisz: @alexpmagalhaes and I wrote a preview for this beautiful study for the print issue. There are many interesting problem related….
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RT @carogutj: Congratulations and thanks to Michael Paries, all lab co-authors and our fantastic collaborators.@ShabekLab, @amiriamguercio.….
pnas.org
During arbuscular mycorrhiza (AM) symbiosis AM fungi form tree-shaped structures called arbuscules in root cortex cells of host plants. Arbuscules ...
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RT @Dev_Cell: Online now: Transport properties of canonical PIN-FORMED proteins from Arabidopsis and the role of the loop domain in auxin t….
cell.com
Polar auxin transport regulates plant growth responses, and Janacek et al. establish that PIN-FORMED auxin exporters have transport properties unique to every individual PIN. These properties depend...
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RT @bulutkarslioglu: The @MPI_MolGen logo made of our beloved paused blastocysts! Images by @VvdWeijden artwork by @rene_buschow @ballaschk….
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RT @lila_allou: 📢3-year postdoctoral fellow position available. Interested in gene regulation and deciphering the molecular mechanisms of h….
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RT @PGuckelberger: I am so excited to share this part of my PhD where we tackle the question: What impact do 3D contacts have on how enhanc….
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RT @IreneTalon: Hi! @VallierLab is looking for a PhD student to investigate cellular plasticity in different species using organois. Positi….
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RT @VallierLab: @VallierLab is recruiting a PhD student to study cellular plasticity. The position will be working closely with @IreneTalon….
bihealth.org
Aktuelle Stellenangebote - Berliner Institut für Gesundheitsforschung - Charité und Max-Delbrück-Centrum
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RT @EmmaBat_: DADOS E MEDIDAS DOS ÚLTIMOS 8 ANOS DE GOVERNAÇÃO . Estas eleições trouxeram ao debate público o que foram os últimos 8 anos d….
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This is absolute crazy, to quote the article "Do not blindly trust packages even if they are established ones".
There was a discrepancy in the log2 fold changes for marker gene detection between Seurat and Scanpy. New blog post: Do you really understand log2Fold change in single-cell RNAseq data?
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Exactly what I needed in my data viz life!.
R ggplot2 color palettes inspired by Hayao Miyazaki’s animes by Joanna #rstats #dataviz #ggplot2 #dataanalytics #datascience.
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Congrats @alida_bouatta! The paper looks awesome, especially the microscopy!.
Specific ROPGEFs drive pollen germination in Arabidopsis!. I'm happy to share the first preprint from my group!.. It’s the project of my 1st PhD student Alida Bouatta @alida_bouatta & Andrea Lepper @TU_Muenchen #Polarity #Pollen #ROPGEFs #microscopy.1/6
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RT @uhammes: Were hiring! @BoudkerLab and I are looking for jointly supervised PhD student or PostDoc to investigate structure/function of….
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RT @bulutkarslioglu: Literal food for thought needed. Superb new cafeteria space. Please spread the word if you know anyone who might be in….
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