Introducing BenchBB and the community paper of the Protein Design Competition 🎉. We wrote a community paper about our Protein Design Competition, teaming up with your favourite protein designers from both rounds. Excited to announce that this is now on Biorxiv 🙌

Thanks a lot to @Filippo_Stocco_ & @CotetTudor for writing this piece and the valuable feedback from @ferruz_noelia, Michele Garribo & @TheGermanPole.

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How can you use Reinforcement Learning to make better proteins and what does a “Move 37” moment in protein design look like?. We’re taking a look at ProtRL: a framework for aligning protein language models to your desired distributions using reinforcement learning. Filippo Stocco

Want to learn more? -> Check out Chai's report Want to validate your own models and test your proteins in the lab? -> Just go to our website and set up your first experiment

Chai Discovery just released their new model Chai-2, validated on Adaptyv! . Chai-2 enables generation of de novo proteins and epitope-specific antibodies using a multimodal generative architecture that integrates all-atom structure prediction and generative modeling. Chai

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We're hiring! Come work with us to democratize protein engineering. At Adaptyv, our high-throughput cloud lab enables protein designers to experimentally validate their proteins with the click of a button. We're building advanced molecular biology workflows, assay automation

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Pro-1, a protein design model by @hla_michael, doesn’t just propose mutations — it explains why it made them. We tested 19 of its FGF-1 designs in our lab and 3 of them improved thermostability while maintaining binding. In this protein designer spotlight we explain how

RT @KathyYWei1: Even in the era of AlphaFold, can't help but get super excited at a beautiful xtal! Thanks @adaptyvbio .

RT @julian_englert: Cool work by @hla_michael who designed proteins using his reasoning model Pro-1 and validated them in our lab at @adapt….

RT @julian_englert: Speaking at @SynBioBeta today on the panel on “AI-Powered Biological Design”! We’ll explore where AI is accelerating pr….

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Thanks a lot to everyone that contributed -- without the efforts of the protein design community this wouldn't have been possible!. We close the paper by creating BenchBB, the Bench-tested Binder Benchmark — a curated set of 7 protein targets designed to capture diverse binder.

Blog post: .

Biorxiv:

RT @julian_englert: It's so cool how @v0 + @supabase make it easy for scientists to build their own software 🧪💻. Today we ran an internal h….

RT @julian_englert: Can you build this? Then come work with us at @adaptyvbio. Adaptyv is the cloud lab for protein designers. Our high-t….

RT @julian_englert: It's @appliedmldays! 🎉. Together with the @cradlebio team we're hosting two great tracks on ML-driven protein engineeri….