Isaac Kohane
@zakkohane
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Computer science + Biomedicine = Medicine as a Knowledge Processing Discipline @harvardMED @HarvardDBMI Prof/Dept Chair https://t.co/6qcUd2RfDs MD/PhD @NEJM AI EIC
Boston, MA
Joined April 2009
Looking forward to the chat about AI tools in health insurance coverage decisions Join @umnconsortium — & me — for a free event to learn more. 📅Wed, Dec 10 ⏰Noon-1:30pm CT 📍Zoom Register: https://t.co/kB9VUqV1jl
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Useful summary of incidental imaging findings in Grokipedia but where do we start an article on incidental genomics findings
grokipedia.com
An incidental imaging finding, often referred to as an incidentaloma, is an abnormality or lesion detected on medical imaging studies that is unrelated to the primary indication for the examination,...
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Big Nerd News! Microsoft is open sourcing Zork I, II, & III! I guess a chunk of my weekend is toast https://t.co/NHNZ0t0yfY
opensource.microsoft.com
Microsoft’s Open Source Programs Office (OSPO), Team Xbox, and Activision are making Zork I, Zork II, and Zork III available under the MIT License.
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I’m afraid this is the most perfect company swag I’ve ever seen
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Today in @Nature we report a new prime editing strategy that can rescue a common cause of many genetic diseases in a disease-agnostic manner. This approach converts a redundant endogenous tRNA into an optimized suppressor tRNA, enabling a single prime edit to rescue premature
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Dec 16, 11 AM–3 PM ET. Practical AI for oncology with @DrAbernethyFDA, @zakkohane, Betsy O’Donnell (@DanaFarber), Dr Connie Lehman (@MassGenBrigham), @LucioGordanMD, David Penberthy. Free reg: https://t.co/JQroVUFVxc
#AIinOncology #PrecisionOncology #ClinicalAI #CancerCare
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We still need a good UX to share clinical info remotely during online interactions. Proposal: I’ve drafted and prototyped a "SMART Check-in" protocol inspired by W3C Digital Credentials. Background: SMART Health Cards and Links standardize data + simple workflows for manual QR
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Liberation for many elderly who want driving autonomy but know that they are less safe drivers than they would like. This is a public health intervention. Looking forward to Tesla scaling up and further democratizing access.
NEWS: Waymo has announced that they are introducing fully autonomous driving in five new cities: Miami, Dallas, Houston, San Antonio, and Orlando. Operations start today in Miami, and will begin in the remaining four cities over the coming weeks, ahead of opening doors to
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We need good clinical questions for therapeutic decision making in rare/undiagnosed disease to help and AI hackathon:
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Sean Tan ‘27 Assistant Conductor is earning a BS in symbolic systems (AI) and BA in music (conducting)
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The craziest part of American healthcare isn’t that an MRI can cost $8,000. It’s that the $8,000 MRI survives right next to the $400 MRI, and nobody can trade the spread. That’s not a market. When prices become data and data becomes tradable, the charade ends. Capital hunts
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@zakkohane @Apple @phaseofmatter The Apple export behavior appears to be a bug (regression; FHIR resources used to be included in individual JSON files; should presumably work again at some point).
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Don't make me tap the sign
We will now be able to discover new drugs 1000s of times faster. Thanks to AI, all diseases will be curable during the 2030s. MADD - Multi Agent Drug Discovery Orchestra, a multi agent AI system designed to massively accelerate the early stages of drug discovery, especially
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Even internal consistency for @MedicareGov is important. With AI, a global spreadsheet at CMMI that checks for these inconsistencies is feasible and could be made public and available for direct AI-augmented conversations with the public and policy makers. HT @arjunmanrai
Crazy. The Medicare allowed payment for a doctor to read a coronary CT angio is about a hundred bucks. But Medicare will pay an AI company $1000? How did this happen?
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Endocrinology news pops up in weird places.
An analysis of Hitler's genome reveals he had Kallmann syndrome, a disorder that can prevent sexual development and causes low testosterone. He also had a top 1% polygenic score for schizophrenia, autism and bipolar. Hitler had no Jewish ancestry. https://t.co/vJX5FrjRPT
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An analysis of Hitler's genome reveals he had Kallmann syndrome, a disorder that can prevent sexual development and causes low testosterone. He also had a top 1% polygenic score for schizophrenia, autism and bipolar. Hitler had no Jewish ancestry. https://t.co/vJX5FrjRPT
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Exciting expansion! @Waymo now serves the whole SF Bay Area Peninsula from SF to San Jose and is taking riders on freeways. https://t.co/fNgqQtHB7b
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I took delivery of a beautiful new shiny HW4 Tesla Model X today, so I immediately took it out for an FSD test drive, a bit like I used to do almost daily for 5 years. Basically... I'm amazed - it drives really, really well, smooth, confident, noticeably better than what I'm used
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