Zhonghua Liu
@ZHLiu13
Followers
160
Following
98
Media
5
Statuses
45
Assistant Professor in Biostatistics, Columbia University
New York City
Joined March 2021
What to Know about a New Blood Test for Alzheimer’s
columbiadoctors.org
A new FDA-approved blood test can detect Alzheimer’s earlier and more easily. Our expert explains how Alzheimer's blood tests work and the benefits they offer.
0
0
1
Last spring, the U.S. Food and Drug Administration (FDA) approved the first blood test to help diagnose Alzheimer’s. @ColumbiaMSPH's Dr. Zhonghua Liu explains how the new FDA-approved test works and the ways it can benefit patients.
columbiadoctors.org
A new FDA-approved blood test can detect Alzheimer’s earlier and more easily. Our expert explains how Alzheimer's blood tests work and the benefits they offer.
1
5
6
We're thrilled to share our latest publication, A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies, in @NatComputSci. Sincerely thanks to @XihongLin for incredible mentorship, @muzizimumu1, @ZHLiu13, @pnatarajanmd, Dr.
📢Out now! @xihaoli, @pnatarajanmd, @muzizimumu1, @ZHLiu13, @XihongLin, and colleagues from @nih_nhlbi present a framework for functionally-informed multi-trait rare variant analysis of biobank-scale sequencing studies. https://t.co/judklgK1eO 🔓 https://t.co/0ua7YW6Dko
3
23
74
Innovation meets discovery! Columbia Mailman researchers unveil a cutting-edge pipeline that links protein biomarkers to Alzheimer's and predicts 3D changes, paving the way for early detection & breakthrough treatments. @ZHLiu13 @GaryWMiller3
publichealth.columbia.edu
Researchers designed novel computational pipeline designed to identify protein biomarkers associated with complex diseases
7
49
209
Novel all-in-one computational pipeline offers insights into Alzheimer's mechanisms and potential drug targets https://t.co/4DkuDHOzce via @medical_xpress
medicalxpress.com
Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including...
0
1
2
Excited to share our latest work in Cell Genomics! Using a novel MR method integrated with AlphaFold3, we identify Alzheimer’s-associated proteins with 3D structural changes. https://t.co/Q5lnLo7zqn
@BaccarelliAA @GaryWMiller3 @ColumbiaMSPH @CellGenomics
cell.com
Yao et al. develop a computational pipeline integrating a robust Mendelian randomization method with AlphaFold3 to select valid pQTL instruments, identify causal protein biomarkers, and predict 3D...
2
7
39
Identification and Inference with Invalid Instruments | Annual Reviews -
annualreviews.org
Instrumental variables (IVs) are widely used to study the causal effect of an exposure on an outcome in the presence of unmeasured confounding. IVs require an instrument, a variable that (a) is...
0
1
3
Deciphering causal proteins in Alzheimer’s disease: A novel Mendelian randomization method integrated with AlphaFold3 for 3D structure prediction • This study introduces MR-SPI, a novel Mendelian randomization method, to address biases in identifying causal protein biomarkers
0
11
36
We aim to characterize the association between multiple co-occurring climate threats and neurodegeneration. Many statistical and data science challenges are waiting to be resolved! https://t.co/fjaTkoRpn8
publichealth.columbia.edu
The new center, Climate and Health: Action and Research for Transformational Change, is led by public health researchers.
0
4
20
Congratulations and so well deserved, @hongtuzhu1!👏
Please join us in congratulating Dr. Hongtu Zhu from our department for being named editor of JASA-Applications and Case Studies! https://t.co/qn4bPCeFWq
0
1
11
Gave a talk at STATGEN 2024 on Recent Developments in Mendelian Randomization Methods for Causal Inference. Thanks for the great turnout! #TrialSampleTwitter - via #Whova event app
0
0
1
Gave a talk at STATGEN 2024 on Recent Developments in Mendelian Randomization Methods for Causal Inference. Thanks for the great turnout! #TrialSampleTwitter - via #Whova event app
0
1
10
Congratulations @XihongLin! Such a well-deserved honor for a visionary leader and outstanding mentor. Feeling extremely proud of you! 🎉👏
Honored to be inducted to @theNASciences on Friday, April 26 together with Rob Kass and celebrated it with @SusanMurphylab1, Iain Johnstone and Rob
2
6
38
Good news! My article received enough citations to be a #TopCitedArticle in its journal.
3
0
3
Learnt a lot from a conversation with Prof. Pearl on instrument variable and mediation
0
0
5
A recent study published in @ana_journals which included 1644 people found that a slower pace of aging mediated the relationship of healthy diet with reduced dementia risk. https://t.co/TwVBm4FQjp 2/8
1
2
4
Our paper appeared on the cover of the 2/14 issue of @CellGenomics. By performing joint mediation and interaction analysis, this paper showed the risk of nasopharyngeal carcinoma (NPC) associated with HLA variants depended on infection of a high-risk EBV subtype (1/2)
1
5
46
ImmuneMirror: A machine learning-based integrative pipeline and web server for neoantigen prediction
academic.oup.com
Abstract. Neoantigens are derived from somatic mutations in the tumors but are absent in normal tissues. Emerging evidence suggests that neoantigens can st
0
0
7
Host genetic variants, Epstein-Barr virus subtypes, and the risk of nasopharyngeal carcinoma: Assessment of interaction and mediation: Cell Genomics
cell.com
Xu et al. revealed that the risk of nasopharyngeal carcinoma (NPC) associated with HLA variants depended on infection of a high-risk EBV subtype, indicating that most NPC risk could theoretically be...
1
1
8