I am delighted to announce that I am starting my lab next month in @OxfordOncology. It is such a privilege to be a part of this storied institution!.Also, we are hiring - if chromosomal instability and cancer biology excite you, come join the fun!

RT @AdamsBioAging: Cytosolic DNA crosstalk in senescence: a new axis of inflammatory signaling-------I'm excited to collaborate with Joao P….

Blazing-fast image creation – using just your voice. Try Grok Imagine.

RT @whitefishlab: The implications are pretty clear: while DNA mutations and chemical signals from the environment are important, physical….

RT @eLife: How do cells clean up misfolded proteins when they divide?. This study finds that the cleanup crew includes the ER chaperone BiP….

RT @loxstoplox: I’m excited, relieved, and honored to announce that my paper describing non-canonical mitotic mechanisms in the early mouse….

RT @Samuel_Bakhoum: Another elegant study by @eileen_parkes group showing how chronic #cGAS #STING activation from #Chromosomal_instability….

RT @CharlesSwanton: Now the incredible Mariam Jamal-Hanjani presenting data from the TRACERx Peace cohorts defining the metastatic cascade….

RT @RuggeroDavide: And we couldn't make it without @PCFnews @pcarroll_ and Benioff Initiative for Prostate Cancer Research support!. htt….

RT @dhruva_biswas: Excited to share our new Research Briefing, to accompany our recent work on ORACLE—outlining aims, discoveries, and futu….

We are fortunate to get a trial of the NL5+ confocal system from @confocal_nl which is a total gamechanger. @TheCrick just got a NL5+ system after the trial -- can't wait to have more fun with it♥️!! 4/4.

The biggest nemesis of live microscopy is light toxicity. The success rate for mitotic imaging is painfully low because one has to balance resolution vs cell death – either you have a blurry movie or a high-resolution movie showing a dead cell. 3/4.

The cover is designed by @jeroen_claus @phospho, who converted a mitotis time-lapse movie into some awesome cover art. One can see that chromosomes (white) align and then pulled apart by tubulin (red) as the cell divides, showing lagging chromsomes and chromosomal bridges. 2/4.

We’re thrilled to see our research has been highlighted as the cover of NCB this month 🎉 🎉. We are honoured to share this issue with thought-provoking articles investigating multiple aspects of chromosomal instability and mitosis @fachinettilab @thecesarelab. 🧵 1/4.

RT @S_J_Aitken: Taking these results together, we found that there is strong interaction between genetic background, specific driver mutati….

RT @NatureCellBio: 💫NEW by @Wtlu3 @CharlesSwanton @nnennayaKanu @bartek_Lab & co: analyses of data from the TRACERx cohort of #LungCancer p….

We hope this is useful for the field. Our paper can be found here:.Or the readcube link below:..Happy new year everyone!!!.

We all depends on our wider community to progress our craft . A huge shoutout to @LabLegube @DiffleyLab @JingkunZeng @BertolinAgos @jstarklab @Samuel_Bakhoum and Martin Bushell lab @CRUK_SI for reagents and/or discussions along the way - it does take a proverbial village!.

It is a privilege to work with a bunch of passionate and talented bioinformaticians @jrm_black @oriol_pich @cbailey_58 @CarlosEcolEvol @fgimenovaliente @IUsaite @KerstinThol @drmaiseb @dhruva_biswas.who are dedicated to integrating real-life data with experimental results.

I would like to thank @panoszalmas and high throughput screening core @TheCrick.They gave this project a solid foundation for us to build on. Thank you to all the collaborators @McclellandLab @taponlab @kasperfugger @nickymcgranahan @nbirkbak @kevlitchfield &Mariam Jamal-Hanjani.

As a "wet" scientist, it is unique to do reverse translation by start cold turkey from a gene name (FAT1) and explore its function in the capacity of the DDR and CIN. I would like to thank the patients and their families, without which we would not be proceed with this project.