UNSW Biotechnology & Biomolecular Sciences
@UNSWBABS
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School of BABS at @UNSWScience | posts from our staff, students, alumni & friends (which don't necessarily represent UNSW views)
Bedegal Land (Sydney, NSW)
Joined September 2015
New review out in @NAR_Open! 🔎 What makes a bacterial small RNA work? We discuss: 🧬 Sequence features 🤝 Hfq, ProQ & RNA chaperones ✂️ RNase E & degradosome interactions 🧪 Lessons for synthetic RNA design 📖Read: https://t.co/I7kWwFVa9c With @jaitreeau @UNSWBABS @DavidLalaouna
academic.oup.com
Abstract. Bacterial small RNAs (sRNAs) are key regulators of gene expression, interacting with target messenger RNAs (mRNAs) through imperfect base pairing
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Our recent paper looking at history of flagellar motility now online in final form @ISMEJournal We looked at 10,000 species to map the diversity and history of the bacterial #flagellar motor across the tree of life. @UNSWBABS
@UNSWScience
https://t.co/ded2vSGC5h
academic.oup.com
Abstract. Bacterial swimming is mostly powered by the bacterial flagellar motor and the number of proteins involved in the flagellar motor can vary. Quanti
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What can wastewater tell us about viruses? 💩🚽🧬📈 During the COVID-19 pandemic many labs turned to wastewater monitoring to detect viruses. However, @WhiteLabUNSW has been using wastewater for over 10 years to monitor circulating norovirus 🤮. 🧵 https://t.co/iMBKQEy2X6
tandfonline.com
Norovirus causes an estimated 699 million cases of gastroenteritis and 219,000 deaths each year. Historically, novel strains with a genogroup II genotype 4 (GII.4) capsid have emerged every 3–5 yea...
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Sydney #RNA people, @SydneyRNASalon, don't miss out on today's @UNSWBABS & @UNSWRNA presentation by Prof. Eric Westhof Limited seats and drinks to follow!
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Had an absolute blast presenting a poster at my first international conference, Deuel Conference on Lipids 2025 in beautiful Long Beach, California. #ASBMBDeuel @ASBMB
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It is an honour to have been awarded the FEMS Microbiology Reviews outstanding poster award at the #blastmeeting2025! Thank you to the judges and all those who came to my poster and talked all things flagellin! @FEMSmicro @UNSWBABS @UNSWScience @BlastMeetings
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As part of the @unswscience "SciX@UNSW" program we hosted a tour of our genomics facility! This program supports passionate high school students who are eager to delve into scientific research, giving them a taste of this career path. #scix
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Congratulations Hatu on the first publication from your PhD 😊 https://t.co/t86CkrH2Qh
@CyrilleBoyer61 @UNSWBABS
onlinelibrary.wiley.com
Invasive fungal infections cause over 3.7 million deaths annually, emphasizing the need for novel antifungal agents. This study explores multiblock terpolymers with defined arrangements of cationic,...
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Excited to share my first paper! 🦠🔬 We investigate the human macrophage response to the emerging enteric pathogen #Aeromonas veronii, exploring inflammation, apoptosis, and histone downregulation. Explore our findings here: https://t.co/Oxlh77oesP
@UNSWBABS @UNSWScience
tandfonline.com
This study investigated the pathogenic mechanisms of Aeromonas veronii in macrophages. THP-1 derived macrophages were used as a human macrophage model and were treated with A. veronii strain AS1 is...
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The first of many novel Antarctic fungi to be described by the #Ferrarilab in collab with Brett Summerell and @BotanicSydney @AlintaFurnell @XabiVC @jordan_vink marcwilkins Penicillium psychrofluorescens sp. nov., a naturally autofluorescent Antarc fungus
tandfonline.com
A new fungal species, Penicillium psychrofluorescens sp. nov. is described as a member of section Torulomyces. The new species is sister to P. catalonicum, and was isolated from soil collected from...
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2nd ever @egiannoulatou @phatmattbaker double header, today @PKU1898. Hosted by @OxfordPhysics PhD colleague Prof Bai Fan it was great to represent @UNSWBABS @UNSWScience & @VictorChangInst @UNSWMedicine w/ #flagellar & #SCAD research. Shoutout @LEGO_Group for childcare assist.
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Check out the latest Ferrari Lab publication! 🚨 Discover how microbial life at Robinson Ridge, East Antarctica ❄️, shifts up a hillslope, across fine spatial scales and vertical layers. 🧊🏔️❄️ https://t.co/zu3wSXSRas
@ferrari_belinda @UNSWBABS
#MicrobialEcology #Antarctica
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Our last publication for the year which highlights our strong collaboration with @SpeddingTim and Dan Wilkins. Congratulations team. @eden_zh @nathali_micro @UNSWBABS @AusAntarctic Fine-scale landscape heterogeneity drives microbial community structur...
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Exciting times in the #RegRNALab! We just got our growth chamber 🌱. Getting ready for our #2ToTango #FT24 @arc_gov_au experiments!!! Thanks to the @UNSWBABS team for all your help setting it up and @UNSWRNA for the generous startup + ongoing support! #RNA
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Grateful to have contributed to a study led by Feifei Su @UNSW, exploring how NEGR1 deficiency affects GAD65 accumulation, synaptic GABA synthesis, and feeding behavior. NEGR1 influences GABAergic signaling, with potential links to psychiatric disorders. [ https://t.co/h8cUMgcGtx]
onlinelibrary.wiley.com
GAD65 (pink) is the enzyme synthesizing the inhibitory neurotransmitter GABA in the cytosol. We show that GAD65 attaches to the plasma membrane where it is sorted to membranes of budding endosomes/...
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Bowling 🎳 w/ @UNSWBABS and our lab for end of year 🎉🍕🍻. Fun bowl-off which our lab lost. Eerie to be inside in the dark then exit after a few VBs to blazing ☀️🌞 32C. Shout out to HoS @shanetgrey & School Mgr Michael Bowen leading us on and off the lanes. #buckhunter also.
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"Rescue of bacterial motility using two and three-species FliC chimeras" In this pre-print out we studied the effect of flagellin (FliC) outer domain chimeras on bacterial motility. @UNSWScience @UNSWBABS
https://t.co/szTw82QrGz
biorxiv.org
The bacterial flagellar filament acts as a propeller to drive most bacterial swimming. The filament is made of flagellin, known as FliC in Escherichia coli, Salmonella Typhimurium and Pseudomonas...
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This work was led by #PhD student Jamiema Sara Philip, supported by @HFSP w/ @SBSatEd @AucklandUni @UNSWBABS contributions from @pseudomoaner @NickJMatzke Caroline Puente-Lelievre @JacobScadden, – and initially started as an undergrad @UNSWEngineering proj. w Sehhaj Grewal.
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"Easy come, easier go: mapping the loss of flagellar motility across the tree of life" 🌱🔬 We analysed ~11,000 bacterial genomes to examine how flagellar motility has evolved 🏊♂️➡️🛑 @UNSWBABS @UNSWScience
https://t.co/8EGMNaJuQ7
biorxiv.org
Most bacterial swimming is powered by the bacterial flagellar motor, a nanomachine that self-assembles from up to 45 proteins into a membrane-spanning complex. The number and types of proteins...
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