NV Lab
@UH_NVLab
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M.D. Anderson Professor @UHEngineering. Interested in cancer #immunotherapy, #vaccines, #immunology
Houston, TX
Joined February 2020
Our lab works at the interface of engineering, immunology and immunotherapy. https://t.co/WGJM4bvKQq
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Our latest work was published in @HoustonChron! University of Houston nasal vaccine prevents COVID from spreading :
houstonchronicle.com
A team of researchers from the University of Houston have developed a new vaccine to...
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Dr. Ankita Leekha from the @UH_NVLab led the development of NanoSTING 🦂, a nanoparticle formulation of the endogenous STING agonist, 2′−3′ cGAMP, to function as an immune activator and demonstrated its safety in mice and rats. 🐁 🐀 More here: https://t.co/bspSBG4m1e
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Many congratulations to our Dr. Sunil Acharya @sunilacharya13 for his exciting research on CD70-targeting CAR NK cells, published in Cancer Discovery! Sunil and his co-authors showed that the incorporation of CD28 costimulation, which is normally absent in NK cells, in the CAR
Now online in @CD_AACR: CD28 Costimulation Augments CAR Signaling in NK cells via the LCK/CD3ζ/ZAP70 Signaling Axis - by @sunilacharya13 @lab_rezvani and colleagues https://t.co/ZeTtmW85O6
@MDAndersonNews
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CD28 co-stimulation in NK cells? Who knew! New @CD_AACR paper from @lab_rezvani @MDAndersonNews showing CD28 costimulation can augment CAR signaling in mature NK cells via the LCK/CD3Z/ZAP70 axis. https://t.co/aIZ8d2Bns6
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Latest UH press release featuring our new Nature Cancer paper! https://t.co/9PXIPuSwU8
@UHEngineering @UH_ChBE @UHouston
uh.edu
Improves Outlook for Lymphoma Patients
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Check out the latest articles @NatureCancer "Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling"
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Dynamic functional profiling of T-cell therapies uncover a subset of T cells, labeled CD8-fit, that are motile serial killers and are associated with clinical responses in diffuse B cell lymphoma patients. https://t.co/xr9jHn8P1Z (No Paywall) https://t.co/KSAVlNoPSK
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An intranasal nanoparticle vaccine elicits protective immunity against Mycobacterium tuberculosis @UHEngineering @UH_ChBE
https://t.co/hxE7amf9nY
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Next - @UH_NVLab @MDAndersonNews @UHouston is telling us about the metabolic plasticity of T-cell Therapies, with an intriguing title, "digest more fat"! @MelanomaReAlli
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Understanding redundancies in cytotoxic mechanisms employed by CAR T cells in the killing of tumors @UHEngineering @UH_ChBE Link: https://t.co/ukdHsjRwSJ
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Congratulations to @CellChorus for being announced as a 2023 Houston Innovation Awards finalist in the Life Science Business sector! #startups #innovation #AI #immunology @_danmeyer Link:
houston.innovationmap.com
In just three weeks, all of Houston's innovation ecosystem will gather to celebrate the hard work of startups, entrepreneurs, investors, mentors, and more — and over 50 honorees will be recognized...
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Trained neural network detects apoptotic bodies of human melanoma cells without fluorescent labeling @UHEngineering @UH_ChBE #MachineLearning #Immunology Link: https://t.co/TlyxVaZBe4
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Celebrating the induction of four of my @UHouston colleagues as senior members of the National Academy of Inventors. Congratulations Navin Varadarajan, @tjmountziaris, James Briggs and Gomika Udugamasooriya
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Linking extracellular vesicle (EV) secretion to metastasis at the single-cell level @MohsenFathi1993 @UH_ChBE @iScience_CP iScience article: https://t.co/XHor3oogvI
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Dr. Navin Varadarajan's team (@UH_NVLab) at @UHouston developed a method to identify 🔎 signatures of #ExtracellularVesicle secretion in metastatic #BreastCancer through functional single-cell profiling. More in @iScience_CP 💡 https://t.co/8vvWrpZb8A
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New tech developed at @UHEngineering shows promise as a weapon against #lymphoma
https://t.co/aj9EuM9NMa
#nanotech
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(1/2) This issue of #Parameters features stories on @UH_ChBE Prof. Gül Zerze's academic path; new grants for @UH_NVLab (immunotherapy) and @ekourent (diagnostics); an ASEE award for postdoc Dr. LeShorn Benjamin (with @dr_jah_director); awards for Profs. Anil Bhowmick, ...
Today we are excited to launch the fall 2022 issue of #Parameters. In this issue, we highlight some of the rising stars to have recently joined the #CullenCollege, along with their incredible work. ( 1 of 3)
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Incredibly proud of Ye Ethan Li for having his PhD project published in Nat Med. His paper shows that trogocytosis drives relapse post CAR NK therapy & that modulating NK signaling can improve CAR NK efficacy. Congratulations Ethan! @KenChen @UH_NVLab
https://t.co/Wtpc3dWtPG
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