CellChorus
@CellChorus
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Life exists in motion. CellChorus® provides a high-throughput platform for evaluating how individual cells move, behave and interact.
Houston, TX | South SF, CA
Joined July 2020
Attending SITC 2024? Four abstracts from CellChorus and collaborators feature TIMING data! Join us to learn how dynamic single-cell analysis improves screening donors, enhancing ADCC, quantifying potency/viability, and more. https://t.co/u5Ay8e37u2
@sitcancer
cellchorus.com
Four abstracts at SITC 2024 to feature TIMING data. Applications of TIMING data include screening donors, enhancing ADCC, quantifying potency/viability, and more.
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Trump’s decision to halt federal virtually all federal grants and loans is lawless, destructive, dangerous, and cruel. It is illegal. It is unconstitutional. It’s nothing less than Project 2025 by another name. Congress must act.
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CellChorus announced that the company, along with The University of Houston, has been awarded up to $2.5 million in funding.
houston.innovationmap.com
This week, CellChorus announced that the company, along with The University of Houston, has been awarded up to $2.5 million in funding from the National Center for Advancing Translational Sciences...
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In Brief This Week: Bruker, Qiagen, Prenetics, CellChorus, T2 Biosystems, More
genomeweb.com
News items for the week of Oct. 7, 2024.
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Attending #SITC24 this week?Be sure to check out the 𝒇𝒐𝒖𝒓 presentations featuring data from @CellChorus' single-cell analysis technology!
cellchorus.com
Four abstracts at SITC 2024 to feature TIMING data. Applications of TIMING data include screening donors, enhancing ADCC, quantifying potency/viability, and more.
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Congrats to @sunilacharya13, @lab_rezvani & collaborators for publishing in Cancer Discovery how CD28 costimulation enhances CAR-NK cell function! CAR27 NK cells with CD28-based costimulation were ~3x more likely to exhibit serial killing. Learn more: https://t.co/Gf1J3F5P5S
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💥 @CellChorus and @UHouston received a $2.5 million STTR fast-track award for innovations in AI/ML from the @ncats_nih_gov at @NIH. Learn more: https://t.co/hgnuIM4t2t
#ai #artificialIntelligence #ml #machineLearning #singleCell #singleCellAnalysis @UHEngineering
cellchorus.com
The National Center for Advancing Translational Sciences (NCATS) of the NIH has awarded CellChorus and the University of Houston an STTR Fast-Track grant to advance the development of the Time-lapse...
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Want to learn how to apply TIMING™ for potency and viability analysis in process development? Meet with us at BioProcess International in Boston Sept 25th + 26th. Already registered? Book a meeting in the conference app: https://t.co/3qEXcQXGNi
@BioProcessIntl @InformaConnect
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- TIMING measurements of cell movements during target engagement (synapse) showed that Hy-CAR-Ts maintained significantly more motility than donor-matched Nuc-CAR-T cells. Motility has been linked to strong CAR-T potency and patient response in other studies.
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- TIMING data showed that individual Hy-CAR-T target seeking. contact dynamics, and target killing were just as robust as Nuc-CAR-T. - TIMING data showed that Hy-CAR-T were more resistant to activation-induced cell death (AICD) AICD contributes to exhaustion of CAR-T cells.
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- Hy-CAR-T cells CAR-T from nucleofection (Nuc-CAR-T) in terms of T cell subsets, activation, and pro-inflammatory cytokine secretion. - Hy-CAR-T secreted higher levels of the anti-inflammatory cytokine IL-10, which is linked to better CAR-T function.
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- Hydroporation yields a higher number of transfected cells compared to both nucleofection and electroporation, partly because CAR-T made with hydroporation (Hy-CAR-T) robustly grew and divided.
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The research approach: The team compared hydroporation with nucleofection in the generation of CAR-T cells. Key findings from the research include: - Scaled-up hydroporation can process 5 x 10^8 cells in less than 10 seconds.
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Background: Hydropore from Indee utilizes microfluidic vortex shedding to deliver small molecules, nucleic acids, proteins, and gene-editing complexes to immune cells with low impact to cell viability and function.
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🚨 @IndeeLabs posted a manuscript that applies TIMING™ data from @CellChorus to show that CAR-T cells manufactured with the Indee platform have superior motility and resistance to activation-induced cell death (AICD). https://t.co/KX25PzCaFe
@RBerdeaux @MohsenFathi1993
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Immunotherapy is a powerful tool in fighting cancer, but not all patients respond. However, a team of cancer researchers has recently discovered a new subset of T cells with the @CELLCHORUS (S21) TIMING platform that could improve outcomes for patients:
houston.innovationmap.com
T-cell immunotherapy is all the rage in the world of fighting cancer. A Houston company’s researchers have discovered a new subset of T cells that could be a game changer for patients.
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Check out the latest articles @NatureCancer "Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling"
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💥Publication alert: CAR T cells from individuals with complete response were enriched for migration and serial killing. Learn more about the TIMING™ data: https://t.co/OOFveS2V9z
@NatureCancer @UH_NVLab @MohsenFathi1993 #singleCellAnalysis #CART #cellTherapy
cellchorus.com
Scientists from a comprehensive cancer center and one of the only companies with an approved CAR T cell therapy demonstrate the potential for applying TIMING to identify patients that are likely to...
Check out the latest articles @NatureCancer "Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling"
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Dynamic functional profiling of T-cell therapies uncover a subset of T cells, labeled CD8-fit, that are motile serial killers and are associated with clinical responses in diffuse B cell lymphoma patients. https://t.co/xr9jHn8P1Z (No Paywall) https://t.co/KSAVlNoPSK
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