TimePie (focus on anti-aging science)
@TimePieChina
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@TimePieChina focuses on aging science & longevity news. We would love to be the bridge to academic circle of aging in China. #aging #longevity #senescence
China
Joined January 2022
We're delighted to welcome Dr. Yi Eve Sun join #TimepieLongevityForum2025 as a speaker. Dr. Sun is an internationally recognized expert in stem cell biology and regenerative medicine. She is also the founder of Prometheus Cell Team, China's Only #XPRIZE Healthspan Top 40 Team.
🇨🇳China’s #XPRIZE Healthspan Top 40 team is aiming for regenerative interventions that could extend healthy lifespan to 150 years. We sit down with Dr Yi Eve Sun, Leader of the #PrometheusCell Team, to explore the longevity science behind. @LongevityTech.
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Single-cell transcriptomic and genomic changes in the #ageing human brain, from infancy to #centenarian. TWO age-associated mutational signatures are found that correlate with gene transcription and gene repression. By @ZhipingWeng, @_MikeLodato, et al.
nature.com
Nature - Sequencing analyses of human prefrontal cortex from donors ranging in age from 0.4 to 104 years show that ageing correlates with an accumulation of somatic mutations in short housekeeping...
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Metabolic profiles could serve as an early indicator of accelerated brain aging. 🇨🇳 Scientists uncovered the association between Plasma Metabolomic Profile and Brain Age, identified 64 and 77 metabolites associated with brain age and BAG, respectively, of which 55 overlapped.
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We welcome SiyoMicro, a global leader in synthetic biology innovation and intelligent manufacturing, to join us as a Gold Partner at #TimepieLongevityForum2025.
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Electrical stimulation reprogrammes immune system to heal the body faster. Scientists stimulated human macrophages using a custom bioreactor, causing a shift of macrophages into an anti-inflammatory state that supports faster tissue repair.
cell.com
O’Rourke et al. demonstrate that external delivery of electrical stimulation regulates the function of innate immune cells, macrophages, to favor tissue repair and regeneration. These findings are...
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Dualistic role of #taurine: fueling tumor metabolism while also supporting immune surveillance. Study link:. Will this rising star in anti-aging truly unlock its full potential? More research is definitely needed.
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New study: Nerve-associated macrophages (#NAMs) act as key regulators of fat tissue health across the lifespan. They maintain adipose homeostasis and curb age-related inflammation, linking immune balance to aging and tissue dysfunction.
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Here is the preprint study: .By Macsue Jacques, Kirsten Seale, @mahdi_moqri, @gladyshev_lab, @prof_horvath, @aeteschendorff, et al.
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The most comprehensive picture to date of how ageing modifies our genes: DNA Methylation Ageing Atlas Across 17 Human Tissues. It shows some tissues seem to age faster than others, & reveals universal epigenetic markers of ageing across different organs.
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New review: The emerging Wnt–NAD+ axis is key in cancer, aging & tissue regeneration. @ShukryHabib_Lab. It unites current knowledge of the Wnt–#NAD+ axis and highlights its cooperative roles in maintaining tissue integrity & combating the effects of aging.
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Chinese scientists (@WuXi_Discovery) build a high-throughput system to screen & evaluate #senescence modulators. 🧬.For the first time, IC50/EC50 on fibroblasts can be measured—unlocking a key step for anti-aging drug development. 🚀.
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Scientists from @Lund_Stem built cell-type specific #aging clocks from single-nucleus RNA-seq of human brains.🧠⏳. They predict age with precision, reveal unique #aging paths across cell types, and spot accelerated aging in #Alzheimers & #schizophrenia.
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Winners will receive their grants at the 6th #TimePieLongevityForum (September 20–21, 2025), where some of them will also present their latest discoveries on-site. More details:
timepielongevityforum.com
The 6th TimePie Longevity Forum will be held in September in Shanghai, China.
TimePie Announces Results of Its Inaugural Longevity Research Grant Program.🎉.Through a rigorous single-blind review by our Academic Committee, we are delighted to announce 4 projects were selected for funding. Congratulations to @DONG_Lu_ @Yu_Xuan_Lu, Juntao Bie & @EricDSun!👏
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@DONG_Lu_ @Yu_Xuan_Lu @EricDSun One awardee, Dr. Eric Sun, was unable to accept funding due to personal reasons. We fully respect his decision and honor his selection, while the grant will be distributed among the remaining three scholars.
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TimePie Announces Results of Its Inaugural Longevity Research Grant Program.🎉.Through a rigorous single-blind review by our Academic Committee, we are delighted to announce 4 projects were selected for funding. Congratulations to @DONG_Lu_ @Yu_Xuan_Lu, Juntao Bie & @EricDSun!👏
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McKinsey Health Institute @McKinsey_MGI published a new report focusing on biomedical innovation targeting biological #aging processes. It outlines 7 key shifts needed to turn aging science into real-world health impact & help the field truly flourish.
mckinsey.com
Healthspan science may become more popular in the near future. Stakeholders can shape their roles in this transformative field now.
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Immortal Dragons ($40M longevity fund) invests in @Frontier_Bio to scale 3D biofabrication of organs & tissues. 🧫➡️🫀.Tackling the $150B transplant market, they bet replacement tech can help end aging-related deaths. News Link:
accessnewswire.com
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We welcome #AFU, a Chinese aromatherapy brand, as a Silver Partner for #TimepieLongevityForum2025.
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Unlocking longevity through the comparative biology of aging. @UofR scientists outline key approaches in comparative biology of aging studies, including the study of public mechanisms and private mechanisms. Led by Andrei Seluanov & Vera Gorbunova.
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