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David Vilchez Profile
David Vilchez

@TheVilchezLab

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Biologist, Professor @CECAD_ @UniCologne @UKKoeln. We study aging, age-related diseases, stem cell biology and proteostasis. @thevilchezlab.bsky.social

CECAD Cologne, Germany
Joined July 2013
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@TheVilchezLab
David Vilchez
2 years
New work from the lab @NatureAging!❄️Lowering body temperature extends #longevity. We find that cold-induced #proteostasis prevents #aging and aggregation of proteins that cause age-related diseases #ALS #HuntingtonDisease in C. elegans and human cells
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@TheVilchezLab
David Vilchez
2 months
We have a 4-year postdoc position open in our Research Unit on proteostasis!.The project explores inter-tissue regulation using advanced proteomics approaches. Collaborative & interdisciplinary environment. More details & application here:.
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@TheVilchezLab
David Vilchez
3 months
Excited for the next four years of collaboration on proteostasis research between teams from the University of Cologne, University Hospital of Cologne, and the University of Konstanz.
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@TheVilchezLab
David Vilchez
3 months
Thrilled to announce that our DFG Research Unit on cell-autonomous regulation of proteostasis has been approved for funding! #aging #proteostasis.
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@TheVilchezLab
David Vilchez
4 months
RT @IrinaDudanova: Happy to share our new preprint, where we find that anle138b reduces Huntingtin inclusions and improves disease phenotyp….
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@TheVilchezLab
David Vilchez
8 months
You can also find me here…@thevilchezlab.bsky.social
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@TheVilchezLab
David Vilchez
8 months
Don’t miss this opportunity to join Gabriele’s lab! Exciting science!.
@zaffagg3
Gabriele Zaffagnini
8 months
#Job alert! A #postdoc position in my lab @CECAD_ @UniCologne is open until December 1st. We look for: enthusiasm, curiosity, scientific rigour, and a background in protein quality control, lysosome signalling, or the cell cycle. We offer: fully funded position, top European
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@TheVilchezLab
David Vilchez
9 months
Another Nobel Prize for basic research in C. elegans 👏🏼👏🏼👏🏼.
@NobelPrize
The Nobel Prize
9 months
This year’s medicine laureates Victor Ambros and Gary Ruvkun studied a relatively unassuming 1 mm long roundworm, C. elegans. Despite its small size, C. elegans possesses many specialised cell types such as nerve and muscle cells also found in larger, more complex animals,
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@TheVilchezLab
David Vilchez
9 months
RT @NobelPrize: This year’s medicine laureates Victor Ambros and Gary Ruvkun studied a relatively unassuming 1 mm long roundworm, C. elegan….
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@TheVilchezLab
David Vilchez
10 months
In @elife: Root cap cell corpse clearance limits microbial colonization in Arabidopsis thaliana It was a pleasure to contribute to this work from Alga’s lab @Team_Zuccaro and @neto_flames.
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@TheVilchezLab
David Vilchez
11 months
RT @CECAD_: 🔬 Exciting findings from @TheVilchezLab.in @CellReports! ALS-mutant FUS variants interact with PARP1 & histone H1.2, driving ne….
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@TheVilchezLab
David Vilchez
11 months
Our study shows that ALS-mutant FUS variants interact with PARP1 and histone H1.2, leading to neurodegeneration. However, inhibiting PARylation or reducing H1.2 levels can prevent disease-related changes in human neurons and C. elegans models #ALS.
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@TheVilchezLab
David Vilchez
11 months
This was a titanic effort from Hafiza and the lab @CECAD_ @UniCologne @UKKoeln @CGA_age @EKFStiftung @CellReports.
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@TheVilchezLab
David Vilchez
11 months
New paper from the lab! ALS-FUS mutations cause abnormal PARylation and histone H1.2 interaction, leading to pathological changes: #ALS.
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@TheVilchezLab
David Vilchez
11 months
We have a postdoc/lab manager position available in our lab. The position is initially until December 2025 with the possibility to be extended until December 2032. If interested, please contact me or apply here:
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@TheVilchezLab
David Vilchez
1 year
Congrats Dr. Bilican! Great job, excellent thesis defense! @CGA_age
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@TheVilchezLab
David Vilchez
1 year
And here the job offer and link in English;)
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@TheVilchezLab
David Vilchez
1 year
The contract is initially for 2 years with the possibility to be extended for at least 2 more years.
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@TheVilchezLab
David Vilchez
1 year
We are looking for a motivated postdoc to study the links between aging and amyotrophic lateral sclerosis. The project combines disease modeling using patient-derived iPSCs and C. elegans models. Please apply here or contact me:
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@TheVilchezLab
David Vilchez
1 year
RT @IvanAhelLab: A postdoc position is available in our lab to study ADP-ribosylation and ubiquitylation signalling! We are looking for som….
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@TheVilchezLab
David Vilchez
1 year
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