Lu-Yang Wang
@SynapticTweeter
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If I can see it, I can patch it.
Toronto, Ontario
Joined June 2017
Very proud to share our latest work in collaboration with Amy Yang, Mike Salter, Sean Egan on Intersectin 1 as a pivotal molecule for controlling the emergence of calcium dependent replenishment of the readily releasable pool in developing central synapses.
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Thank you all for congratulating notes which I appreciate profoundly!.
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RT @SickKidsNews: A newly developed molecule could inform future therapies for stroke-related brain injury, finds #SKResearch in @Nature.….
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This novel glutamate binding cavity can be exploited for development of stroke drugs, as exemplified by a new compound LK2 described in our paper.
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Delighted to share our new Nature paper: .This works shows a surprising off-target effect of glutamate on another cell death channel, acid sensing ion channels (ASICs). It turns out that glutamate directly binds to ASICs as a positive allosteric modulator.
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Check it out: most beautiful images of vATPase with a surprising partner on live synaptic vesicles from my brilliant colleague John Rubinstein and his team at SickKids Reaearch Institute & University of Toronto!.
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RT @SamYoungLab: @cacna1a @MDBRide4Rare @ODC_UPenn We are humbled to receive this award. We thank the MDBR and CACNA1A foundation for suppo….
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Many congrats to Amy Yang for her new paper on the role of cerebellum in social recognition memory in Nature Communication published online: So proud of my former trainees for their outstanding work and achievements.
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RT @cacna1a: Thrilled to be sharing the news of our latest grant award to @SamYoungLab @uiowa @IowaMed, signifying a crucial first step in….
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Pleased to share our paper in Neuron showing how Bilirubin acts as an agonist for TRPM2 and aggravates brain injury in stroke.| Home
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awesome program.
HI neuro people. This is a very exciting event! Please have your trainees submit their abstracts.
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Was a pleasure to co-supervise Ke Lai (future post-doc of the Wang Lab) on this project. In our collaboration with Shanghai Jiao Tong University, we have uncovered ASIC channels as a target in treating Neonatal Jaundice. Check out our paper in @ScienceTM.
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RT @KirstyDuncanMP: #ThrowbackThursday to 4 yrs ago, when I first began the important mandate I received from our PM @JustinTrudeau: to ret….
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RIP to my friend, mentor, and collaborator Professor Jim Howe of @YaleMed Pharmacology. Here we are sharing a laugh with Jim’s former student Stacy Irizarry. Neuroscience has just lost one of the great electrophysiologists of our generation but we will never forget Jim’s laugh!
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Another successful collaboration with our colleague Dr. Julie Forman-Kay moves us closer to understanding activity-dep translation of silenced mRNA. Check out our new paper in @PNASNews on reversible mRNA granule formation by FMRP 🔬🧠.#SickKidsVsFragileX
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Following in the steps of our mentors Dr. Harold Atwood & Dr. Milton Charlton to solve the mystery of synaptic heterogeneity, see our new story in @NatureComms : #Nanodomainologists #SeeItPatchIt #SickKidsVsSynapticHeterogeneity
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Talk about a tour de force, Sam Young Jr.'s lab @SamYoungLab has combined virology and neuroscience to challenge conventional wisdom on presynaptic Ca2+ channel regulation in this must-read paper. Congrats Sam! 🍾 Keep listening to the calyx of Held! 👂🧠
Latest research from our lab. We are fired up about the findings and their implications on presynaptic regulation of neuronal circuits.
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RT @SamYoungLab: A tour de force from Lu Wang's lab @SynapticTweeter uncovering the roles of FMRP regulation of synaptic function and impa….
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