SundrudLab
@SundrudL
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Professor, Translation and Mucosal Immunology, Dartmouth Health and Geisel School of Medicine at Dartmouth. Opinions are my own.
Hanover, NH USA
Joined January 2020
Dartmouth Immunology Retreat wrapped up! Having @GwenRandolph_ as our keynote speaker was fantastic. She is brilliant, interactive and so fun to hang out with. Thanks for coming! Dartmouth speakers gave fabulous talks too! @PCRosato1 @SundrudL, Y Huang, M Ackerman, @DionnaKasper
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A lot of Machine Learning (ML) I learned during my Ph.D. was from youtube. I didn't have a guide to do this effectively and thus here it is: A complete guide to studying ML from youtube: 13 best and most recent ML courses available on YouTube. 👩🏫🧵⤵️
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IF staining and imaging of human IPSC derived organoids done by my undergraduate student #FluorescenceFriday #bioart #cellbiology
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I am so excited to share our latest work from the Shaffer Lab! In this manuscript, we describe how the gastric bacterium Helicobacter pylori stimulates STING signaling via cag T4SS-dependent mechanisms. https://t.co/R72NsJrRW0
biorxiv.org
Recognition of foreign nucleic acids is an evolutionarily conserved mechanism by which the host detects microbial threats. Whereas some intracellular bacterial pathogens trigger DNA surveillance...
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#MicroscopyMonday featuring neonatal small intestine stained for alpha tubulin in dark blue, lysosomes in light blue, nuclei in orange and apical membrane in brown. #microscopy #bioart #sciart #histoart #pathart #science
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E16.5 mouse small intestine stained for CDH1 (green), MUC2 (red), HNF4A (white) and DAPI (blue) #MicroscopyMonday #bioart #sciart #pathart #histoart #microscopy
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Our paper on antigen-specific Tfh response evolution during malaria immunization is out in @ScienceImmunology! https://t.co/nYPcYHTSno
science.org
This study defines the clonal evolution and epitope specificity of the human cTFH cell response to Plasmodium falciparum CSP.
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What is a p-value? Wrong answers only 😂 #Bioinformatics #Bioinformation #Statistics #programming #RStats
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Like all important announcements... made a 3 pm on Friday afternoon.... So excited about this soon to be out in mBio paper... and the hard work of Kristin Scoggin (not on twitter) and everyone on this work!
biorxiv.org
Understanding the molecular mechanisms underlying resistance and tolerance to pathogen infection may present the opportunity to develop novel interventions. Resistance is the absence of clinical...
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My lab mates discovered a new way to suppress an immune response involving KIR+ CD8 T cells, regulating autoimmunity and infection. Glad to have contributed! @ScienceMagazine | Mark Davis | @SaligramaLab | @stanfordimmuno
New in Science: Researchers who observed an increase of KIR+CD8+ #Tcells in patients with autoimmune diseases and in those infected with #SARSCoV2 suggest these cells help regulate autoimmune responses following infection. https://t.co/dtPUNMajFa
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So excited to have @ScientistSarah_ as my first @musc_cgs grad student! She has already mastered staining and is generating some beautiful data🤩. Sarah's staining of an intestinal villous taken on a Leica SP8 @LeicaMicro
#bioart #sciart #pathart #GITwitter #ProudPI
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I’m very proud to share my recent work now out in @PLOSPathogens describing how a #Salmonella virulence protein called SteD hijacks a eukaryotic membrane trafficking pathway to regulate its localisation. https://t.co/GcOXWoqGMm
journals.plos.org
Author summary Salmonella enterica is an intracellular pathogen that causes a range of diseases from gastroenteritis to systemic typhoid fever. Its pathogenesis relies on virulence proteins known as...
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Claudin 4 staining in yellow identifying some enteroendocrine cells and enterocytes at the tips of villi. Villin is labeled in purple and nuclei are blue. #MicroscopyMonday #pathart #histoart #micrscopy #fluorescence
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New preprint out! We present a rapid and highly scalable scRNA-seq method. Thousands of samples or millions of cells with only a vortexer. Microfluidics-free single-cell genomics with templated emulsification
biorxiv.org
Single-cell RNA sequencing is now a standard method used to reveal the molecular details of cellular heterogeneity, but current approaches have limitations on speed, scale, and ease of use that stem...
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