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Song Lin Lab Profile
Song Lin Lab

@SongLinLab

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Electrifying organic chemistry since 2016 | Cornell University | For group updates, find us on LinkedIn!

Ithaca, NY
Joined May 2017
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@SongLinLab
Song Lin Lab
10 months
Electrochemical synthesis goes wireless @Nature! Congrats to Bartosz, @JonasRein_ and our friends in the McEuen lab. We’d like to also thank the Lennox Group for their highlight on SPECS:
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nature.com
Nature - High-throughput electrochemistry driven by microelectronic devices.
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@Nature
nature
10 months
Electrochemical reactions for organic synthesis typically require intricate, specialized equipment, slowing progress in this field. Minuscule electric generators now enable faster reaction discovery and development
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@BetleyGroup
Betley Group
10 months
@SongLinLab I suSPECt this will be incredibly useful, nice work🫶
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@JonasRein_
Jonas Rein
10 months
Super excited to see our wireless electrosynthesis microchips in @Nature! SPECS make electrochemical reaction setup as easy as adding SPECS to a reaction and shining light on it! https://t.co/FFchfFmrnq
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nature.com
Nature - A method to produce wireless microelectronic devices powered by light using standard nanofabrication techniques is described to convert any traditional 96-well or 384-well plate into an...
@SongLinLab
Song Lin Lab
10 months
Organic synthesis meets nanofabrication! Introducing SPECS: light-powered microchips that turn any well plate into a wireless high-throughput electrosynthesis reactor at the µL scale. Ideal for reaction discovery, optimization, and library synthesis!
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@SongLinLab
Song Lin Lab
10 months
Organic synthesis meets nanofabrication! Introducing SPECS: light-powered microchips that turn any well plate into a wireless high-throughput electrosynthesis reactor at the µL scale. Ideal for reaction discovery, optimization, and library synthesis!
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nature.com
Nature - A method to produce wireless microelectronic devices powered by light using standard nanofabrication techniques is described to convert any traditional 96-well or 384-well plate into an...
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@SongLinLab
Song Lin Lab
1 year
All good things come in pairs😉 We’re excited to see these works out in @J_A_C_S today! Check them out: https://t.co/PVIGxLM6Qn https://t.co/8blCAPafv2
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pubs.acs.org
Hydride abstraction represents a promising yet underexplored approach in the functionalization of C–H bonds. In this work, we report the oxidation of α-C–H bonds of ethers via oxoammonium catalysis...
@SongLinLab
Song Lin Lab
1 year
No hydridic C–H bond is safe! Back to back in @ChemRxiv today, we report oxoammonium catalyzed oxidation of N-substituted amines and ethers! Featuring high TON, 100 g scale-up, a novel NMR experiment for radical quantification, & QSPR! (1/3)
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@SongLinLab
Song Lin Lab
1 year
Farewell’s are also in order for our beloved post-docs Chenfei, Pierre-Louis and Bartosz🥹We’re sad to see you go, but can’t wait for what your new careers will have in store! Congrats!
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@SongLinLab
Song Lin Lab
1 year
We are thrilled to welcome five stellar 1st year students to the Lin Lab! Congrats to Bofei, Nayan, Evan, Joe and Xiaowei! Here’s to new friends and great science ahead🤩⚡️
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@SongLinLab
Song Lin Lab
1 year
Nothing brightens up a Monday morning like a successful PhD defense! Congratulations to the incredible Dr. @Zhipengluu🤩 Wishing you the best of luck as you begin your career @TakedaPharma 🎉
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@JonasRein_
Jonas Rein
1 year
Super happy to share these two works by our aminoxyl team: Oxoammonium catalyzed hydride abstraction for selective C–H oxidation!
@SongLinLab
Song Lin Lab
1 year
No hydridic C–H bond is safe! Back to back in @ChemRxiv today, we report oxoammonium catalyzed oxidation of N-substituted amines and ethers! Featuring high TON, 100 g scale-up, a novel NMR experiment for radical quantification, & QSPR! (1/3)
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@ThePatilGroup
The Patil Group
1 year
Call for Papers for Joint Special Issues in Tetrahedron Letters and Tetrahedron in honor of Prof. Eric Jacobsen and Prof. Song Lin. @songlin_chem @JacobsenLab For more information Check out: https://t.co/kXHqtzJuDU
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@SongLinLab
Song Lin Lab
1 year
@YukunCheng1 developed the catalytic oxidation of weakly hydridic ethers with either mCPBA or e-chem⚡️. Through a novel relaxometry based NMR experiment for in-situ radical quantification, we unraveled the delicate equilibria among multiple resting states!
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@SongLinLab
Song Lin Lab
1 year
@JonasRein_ and Bartosz developed a catalytic, mild, and selective oxidation of N-substituted amines through HTE and stereoelectronic tuning of aminoxyl radicals. With the help of @BoehringerUS, we then scaled up in batch and flow!  https://t.co/YIODyTUN8e  (2/3)
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@SongLinLab
Song Lin Lab
1 year
No hydridic C–H bond is safe! Back to back in @ChemRxiv today, we report oxoammonium catalyzed oxidation of N-substituted amines and ethers! Featuring high TON, 100 g scale-up, a novel NMR experiment for radical quantification, & QSPR! (1/3)
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@SongLinLab
Song Lin Lab
1 year
ShoNo? More like ShoYes! Now in @J_A_C_S, an electrochemical protocol for α,β-desaturation of N-substituted amines, providing convenient access to β-C–H fluorinated products! A phenomenal group effort by Luiz, Justin, Kaining & our friends at @Genentech⚡️
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pubs.acs.org
Incorporation of C(sp3)–F bonds in biologically active compounds is a common strategy employed in medicinal and agricultural chemistry to tune pharmacokinetic and pharmacodynamic properties. Due to...
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@SongLinLab
Song Lin Lab
1 year
Past and present Lin Lab members Lingxiang, Samson, Cindy and Bartosz are charged up for this year’s Stereochem GRC!⚡️
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@SongLinLab
Song Lin Lab
1 year
Congrats to Dr. @JonasRein_ on a phenomenal PhD defense! A brilliant mind, asymmetric catalysis wizard, and exceptional mentor, your guidance has been invaluable to us all⚡️🧑‍💻Here's to your well-deserved success and many future achievements to come!
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@SongLinLab
Song Lin Lab
1 year
Rising 2nd year Sukwoo also gave an awesome department seminar on his contributions to this work! We are SO proud🤩 Watch out for more to come from this superstar🎉
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@SongLinLab
Song Lin Lab
1 year
Out now in @J_A_C_S! @ju_minsoo, Sukwoo and Halle describe a convenient approach for accessing frustrated radical pairs from tertiary alcohols. We had so much fun scaling up & elaborating our FRP chemistry towards complex molecule synthesis! Check it out:
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pubs.acs.org
Alkoxy radicals are versatile reactive intermediates in organic synthesis. Here, we leverage the principle of frustrated radical pair to provide convenient access to these highly reactive species...
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