Dr. Indrajeet Sharma
@SharmaLabOU
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Presidential Professor of Organic Chemistry at the University of Oklahoma; developing new sustainable synthetic methods using Carbene/Nitrene Chemistry
Norman, OK
Joined August 2011
Please check our Preprint on Skeletal Editing using Blue-Light Promoted Sulfenylnitrenes, a follow-up work of our Science paper (DOI: 10.1126/science.adp0974), for N-Atom Insertion under aqueous conditions at room temperature.
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π¨ Excited to share our latest research, published with @SpringerNature in @NatureComms ! π¨."Fe(OTf)β or Photosensitizer-Free Blue Light Activated Diazo-Thioglycoside Donors for Iterative and Stereoselective Glycosylations." @UofOklahoma .
nature.com
Nature Communications - Conventional methods for thioglycoside activation often rely on precious and toxic platinum group metals. Here, the authors report a catalytic glycosylation strategy...
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Feeling Proud as a Mentor, Sharma Lab shined at the Department Awards Banquet! π proud to share that our lab took home four major departmental awards and also won the Chemistry Trivia Challenge!.Special congratulations to π Upasana, Deacon, Prakash and Surya!
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I am overjoyed to share that I have been awarded the Presidential Professorship β a truly humbling honor! .@UofOklahoma
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Please check out our research on #Skeletal Editing of N-heterocycles using Sulfenylcarbenes published in the Journal of the American Chemical Society (@J_A_C_S ).
pubs.acs.org
Late-stage functionalization (LSF) is a crucial strategy in drug discovery, allowing the modification of complex molecules, including pharmaceuticals, to enhance chemical diversity in drug libraries....
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As the Undergraduate Engagement Committee Chair, I am thrilled to share that our department now has an undergraduate chemistry club. We kicked off the first meeting with an incredible Spring Social, which was a resounding success!
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Our recent publication in Science (Science Vol. 387, Issue 6729, pp. 102β107; DOI: 10.1126/science.adp0974) has been highlighted in Chemical & Engineering News (C&EN), a testament to the impact and significance of our research.
cen.acs.org
Sulfenylnitrene reagent expands N-heterocycles by a single N atom
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What an Incredible Start to 2025! .I am overjoyed to share that our research has been published in Science. As the sole corresponding author, this recognition feels profoundly rewarding and almost surreal.
science.org
Given the prevalence of nitrogen-containing heterocycles in commercial drugs, selectively incorporating a single nitrogen atom is a promising scaffold hopping approach to enhance chemical diversity...
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Please check our preprint on late-stage functionalization using unique sulfenylcarbenes, which exhibit inverse chemoselectivity compared to metal carbenes. Notably, they selectively react with alkenes in the presence of alcohols, carboxylic acids, amines.
linkedin.com
Please check our preprint on late-stage functionalization using unique sulfenylcarbenes, which exhibit inverse chemoselectivity compared to metal carbenes. Notably, they selectively react with...
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I am proud and overjoyed to share the exciting news that Adam Alber, my graduate student who will defend his Ph.D. thesis next month, is embarking on a remarkable new chapter as a tenure-track Assistant Professor at Northwest Oklahoma State University (NWOSU) in the Fall of 2024.
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With immense pride and joy, I want to congratulate the outstanding members of the Sharma Research Group, who are recognized for their contributions to teaching and research at the 2024 Award Banquet of the Department of Chemistry and Biochemistry (OU).
linkedin.com
With immense pride and joy, I want to congratulate the outstanding members of the Sharma Research Group, who are recognized for their contributions and dedication to teaching and research at the 2024...
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RT @kurtilaszlo: On behalf of the Organizing Committee, I am delighted to announce that the inaugural symposium "The Art and Science of Totβ¦.
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Please check our Preprint on Skeletal Editing using unique Sulfenylnitrenes, which allow selective single Nitrogen-Atom Insertion into Pyrroles, Indoles, and Imidazoles for their late-stage functionalization. #Skeletal Editing.View Preprint:
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First, A Very Happy New Year to All my Friends/Colleagues. What a beginning to the year 2024! .Please check out the SHARMA Lab back-to-back papers on Earth-abundant metal carbenes in ACS Catalysis. Here is the link to the second one on Iron Carbenes.
pubs.acs.org
Given its earth abundance, cost-effectiveness, and ecofriendly qualities, iron serves as a promising alternative to precious metals in catalysis. This article presents an iron carbene-initiated...
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First, A Very Happy New Year to All my Friends/Colleagues. What a beginning to the year 2024! .Please check out the SHARMA Lab back-to-back papers on Earth-abundant metal carbenes in ACS Catalysis. Here is the first one.
pubs.acs.org
1,2-cis-Furanosides are present in various biomedically relevant glycosides, and their stereoselective synthesis remains a significant challenge. In this vein, we have developed a stereoselective...
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RT @Bidhan_chem: Glad to share my first publication as a π½πΌπππ±πΌπ° @SharmaLabOU, featuring earth-abundant copper-catalyzed stereoselective 1,β¦.
pubs.acs.org
1,2-cis-Furanosides are present in various biomedically relevant glycosides, and their stereoselective synthesis remains a significant challenge. In this vein, we have developed a stereoselective...
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The Department of Chemistry and Biochemistry at the University of Oklahoma (OU) is seeking applications from candidates for three open-rank (tenure-track/tenured) faculty positions starting in August 2023.
linkedin.com
#facultyjobs #chemistry #organicchemistry #research The Department of Chemistry and Biochemistry in the Dodge Family College of Arts and Sciences at the University of Oklahoma (OU) is seeking...
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Looking for a #postdoctoral Fellow ASAP; Given the current situation of COVID-19 pandemic, preference will be given to candidates, who are already in the USA. If interested, contact Dr. Indrajeet Sharma,"isharma@ou.edu" More information:
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RT @JOC_OL: The SHARMA lab's cool convergent catalytic carbene cascade chemistry for the stereoselective synthesis of oxacycles https://t.cβ¦.
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