Really excited to finally share this work from my internship at @MSFTResearch in summer 2023! This project began when Judith and Kevin raised a simple question: can we develop better latent mappings of olfactory stimuli, such as molecules to odor perception? Summary (1/12):

Applications for @MSFTResearch undergrad research internships for rising juniors and seniors are due Monday Oct 6! Apply to work with us in BioML 👉 https://t.co/QYjsdyEpRQ w/ @KevinKaichuang, @alexijielu, @lorin_crawford, Kristen Severson, @ntenenz, @SarahAlamdari, and more!

I’d say the first Metagenomic Discovery journal club @FutureHouse went well! 20+ of the brightest young molecular biologists from across the Bay Area all gathered in one place. Special thanks to Florian Hoffmann, the first author of the paper we studied, for joining!

Many of the most complex and useful functions in biology emerge at the scale of whole genomes. Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵

I graduated from Berkeley in May, and have moved back to India to help build a new pharma company. Exciting therapeutics will be coming out of Hyderabad in the next few years. Here's part of update I wrote up for friends: https://t.co/dR8cnnrt1V

in the last 12 months Enveda has 1. entered the clinic w soon to be 3 new molecules 2. followed the science pursuing medicines with decacorn potential whilst altering billions of global lives 3. added Mikael Dolsten, former CSO of Pfizer, to the board 4. become a biotech unicorn

Saw a talk this week on the trippiest thing: bacterial cultures on skin induce immune responses. At Michael Fischbach's lab, they demonstrated immunizing mice against tetanus by just dabbing an engineered version of a harmless staph culture on its head. Unlike intramuscular

The emerging blackpill scenario for the next 5 years in biopharma is 8000 techbio startups using AI to make antibody drugs for the same 12 targets and fucking nothing else

a few months ago we @_DimensionCap quietly funded a team of 3 MIT computer scientists & mathematicians at the forefront of ML & physics+simulation for enzyme design. these. guys. are. cracked today they're stealthily building the early team. if you're world class, look below 👇

Strand just closed our $153M Series B. It is hard to put into words what it means to see this team and this vision grow from an idea into a company that can truly change medicine. Grateful. Fired up. And ready to build what’s next.

It was great chatting with @NikoMcCarty in this Q&A about the past and future of AI in biology. Evolution is a unifying theory of biology, and the same principles that design proteins can also design cells, tissues, and organisms. https://t.co/eLHlbRq0Q3

The consensus view today is that Chinese biotechs will remain a licensing shop and won't globally commercialize. Hence it may be a threat to US biotechs but not to US Pharma. IMO this is a naive view and reminiscent of what we said about electric cars, mobile, or batteries.

In 1965, Margaret Dayhoff published the Atlas of Protein Sequence and Structure, which collated the 65 proteins whose amino acid sequences were then known. Inspired by that Atlas, today we are releasing the Dayhoff Atlas of protein sequence data and protein language models.

The genome editing toolkit has expanded a ton over the past decade - this is great for researchers but tough for anyone trying to grasp the basics of the field. That's why I teamed up with @AsimovPress and @EllaWD_PhD to create a streamlined guide to how all these tools work 👇🏼

In case you needed a smile this Tuesday: 10-month-old baby KJ, who received a bespoke gene-editing therapy after a six month scientific sprint - "graduated" from the hospital today and went HOME! YAY SCIENCE! Here's his story: https://t.co/bOjDvHu4WL

Getting to lead this program from inception to development of degraders and “differentiated discovery stage assets” showed me what an incredible team and powerful platform can do. *Every* part of the platform worked, enabling us to rapidly go from DEL screen to validated binders

Biology is blessed. @owl_posting we're on some kind of mind meld because was literally now going through decks and making this to cheer you up lol

This is a good mandate letter. Clear directive, focused priorities, and instilling a sense of urgency.

I am pleased to have made the Time magazine 100 most influential people in philanthropy list:

Join us this Tuesday (05/20) @ 2:30 PM to hear about functional protein mining from @ronboger , a PhD candidate at the @doudna_lab, @UCB_Biophysics

Today, we are launching the first publicly available AI Scientist, via the FutureHouse Platform. Our AI Scientist agents can perform a wide variety of scientific tasks better than humans. By chaining them together, we've already started to discover new biology really fast. With