Şeyma Katrinli
@SeymaKatrinli
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Assistant Professor @EmoryGynOb Psychiatric Genetics, Big Data, Bioinformatics fan. Cat & Coffee person. Pro(ish) gamer.
Atlanta, GA
Joined August 2010
We are growing our team! We are looking to hire a clinical psychologist, two postdocs, and a RA to work on research with MDMA and psilocybin assisted exposure therapy for PTSD, and with the Emory Healthcare Veterans Program. https://t.co/Snw8VHIVuh
#psychedelictherapy #research
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Everyone’s playing with the new ChatGPT image creator so I had to jump on the bandwagon. Naturally, I made Schrödinger’s Grant: simultaneously scored and not discussed until you open eRA Commons🧠📦 🐱 #AcademicLife #NIH #GrantWriting #SchrodingersCat
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🙏Huge thanks to @NIH_ORWH BIRCWH for funding this research and to my incredible collaborators for their support! @EmorySmithLab @alexs_pfc @vas_phd @DrPowersLott BenHunter, Raneeka DeMoss, William C Turner
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📝These results suggest that hormonal stabilization may help manage BPD symptoms—but more clinical research is needed!
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🔎 Key Findings: ➡️Women with BPD experienced more difficulties in relationships, daily living, and mood when naturally cycling. ➡️Ovulation-suppressing contraceptives seemed to buffer these difficulties in BPD but were linked to higher symptoms in women without BPD.
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🎉 Exciting news! My first paper as a PI was just accepted in @npp_journal! 🧠✨ 📖 https://t.co/smQwMxpthU In this study, we explored how ovulation-suppressing contraceptives impact behavioral and functional difficulties in women with Borderline Personality Disorder (BPD).
nature.com
Neuropsychopharmacology - The impact of ovulation-suppressing contraceptives on behavioral and functional difficulties in borderline personality disorder
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6/ Huge thanks to the amazing collaborators and participants who made this study possible 🤝✨ @EmorySmithLab @cnievergelt @JanitzaMontalvo @NikosDaskalakis @NicoleNugentPhD @sheila_rauch @MarcoBoks @LeslieBrickPhD
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5/Understanding how these epigenetic markers influence PTSD onset, progression, and treatment outcomes will be key. Our work provides a roadmap for future studies🚀
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4/ Stratified analyses revealed sex-specific, ancestry-specific, and cohort (civilian vs. military)-type-specific epigenetic signatures. This underscores the need for diverse, inclusive research in PTSD and beyond🌍✨
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3/ We also explored how these CpGs correlate with gene expression and methylation in brain regions implicated in PTSD. Cross-tissue consistency strengthens our findings🧠
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2/ We identified 11 CpG sites significantly associated with PTSD, 9 of these sites are novel! These CpGs shed light on the biological underpinnings of PTSD 🌟
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Thrilled to announce the PGC-PTSD Epigenetics Workgroup @PGCgenetics paper is now live in Genome Medicine 🧬✨ Check it out here: https://t.co/GDtd75hnDp Using data from 23 military and civilian cohorts and 5,077 participants, we conducted the largest EWAS of PTSD to date🧵⬇️
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Come join our team at the Grady Trauma Project (GTP) at Emory in Atlanta as a postdoc! The position is research intensive and will be included within the accredited Emory Postdoctoral Residency in Health Service Psychology program. See comments for more details. Please RT!
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Always feels good to start the new semester with a paper acceptance news 🥳
Excited to share that the PGC-PTSD #Epigenetics group's new paper has been accepted for publication! 🎉 The study developed a blood-based DNA #methylation risk score to predict #PTSD 🧬 Check out the preprint here and stay tuned for the accepted paper:
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AJP Editorial from @SeymaKatrinli @EmoryGynOb + Vasiliki Michopoulos @EmoryMedicine : Decoding Sex Differences in #PTSD Heritability https://t.co/a1E888mJlI
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🧵 The Freeze2 study from PGC-PTSD Epigenetics Workgroup is on preprint! The study analyzed over 5,000 participants from military and civilian cohorts to identify epigenetic changes linked to PTSD 🧬 #PTSD #Epigenetics
https://t.co/dJAvIEY93b
#MentalHealth #Research
medrxiv.org
Background The occurrence of post-traumatic stress disorder (PTSD) following a traumatic event is associated with biological differences that can represent the susceptibility to PTSD, the impact of...
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New research by @EmorySmithLab reveals that accelerated #epigenetic aging in women, particularly in BIPOC, is linked to higher #PTSD risk after environmental disasters, highlighting the critical role of social and environmental factors in #mentalhealth
https://t.co/zDQ4IhVs8i
pubmed.ncbi.nlm.nih.gov
In this cohort study, epigenetic age acceleration was higher in minoritized racial groups and associated with future PTSD diagnosis and severity. These findings support the need for psychoeducation...
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The data are clear: taking sex and gender into account in research and using that knowledge to change health care could benefit billions of people
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We're going to start by highlighting @GLADStudy! The Genetic Links to Anxiety and Depression (GLAD) Study is the world’s largest study of #depression & #anxiety led by @psychgenomics @thaliaeley @KingsCollegeLon @NIHRBioResource.
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Epigenetic Age Acceleration and Disparities in Posttraumatic Stress in Women
jamanetwork.com
This cohort study examines the association of epigenetic age acceleration with probable posttraumatic stress disorder and symptom severity in US women exposed to disaster.
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