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Biointegrated Photonics Lab Profile
Biointegrated Photonics Lab

@SchubertLab

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Science at the interface of biology, chemistry and photonics, discovering new applications of microscopic lasers and sensors @ChemUniCologne

Cologne, Germany
Joined March 2020
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@SchubertLab
Biointegrated Photonics Lab
9 months
Preparing for the exit. For updates from the lab please join us on @bluesky
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@SchubertLab
Biointegrated Photonics Lab
1 year
New paper out @OpticaPubsGroup! Combining #LightSheet microscopy with #microlaser #sensing allows scanning of the entire microlaser surface. Great work by Ross Cowie who built our first ever lightsheet microscope. #OpenAccess
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@SchubertLab
Biointegrated Photonics Lab
1 year
Thanks @rivercyte for visiting and letting us play with this awesome machine! Looking forward to do more experiments and try out new things.
@rivercyte
rivercyte
1 year
Some days we brought our Naiad deformability cytometer to @SchubertLab at @UniCologne - it was awesome to test our device on completely new samples. Looking forward to future experiments! 🔬
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@SchubertLab
Biointegrated Photonics Lab
1 year
RT @TitzeVera: Officially graduated with my PhD from @PhysAstroStAnd! It’s been lovely 4.5 years doing research with @TheGatherLab & @Schub….
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@SchubertLab
Biointegrated Photonics Lab
1 year
And of course, there are many other great droplet-based techniques, check for example those developed by @XavierTrepat, @CampasLab, @GuckLab, David McGloin @AberdeenPhysics ….
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@SchubertLab
Biointegrated Photonics Lab
1 year
If you like this, please also look at the recent paper by @HumarLab that uses a slightly different approach to measure forces with microdroplets
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@SchubertLab
Biointegrated Photonics Lab
1 year
Importantly, DEFORM works even without seeing/imaging the droplets making it perfect for deep tissue and in vivo applications!
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@SchubertLab
Biointegrated Photonics Lab
1 year
This is exactly what we observe! By tuning the surface tension, we can adjust the mechanical properties of the droplets to be deformed inside living biological structure likes 3D #tumour #spheroids.
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@SchubertLab
Biointegrated Photonics Lab
1 year
Our technique, called “DEFORM”, analyses the spectra of microscopic droplet lasers. In theory, a droplet that deforms from a perfect sphere into an #ellipsoid should show a broadening of the laser modes.
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@SchubertLab
Biointegrated Photonics Lab
1 year
Forces play a critical role in #embryogenesis and #cancer progression. There are many techniques to measure biological forces but most are based on imaging, making it difficult to measure inside tissue. (see image of a Drosophila larva at the right which is completely blurred)
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@SchubertLab
Biointegrated Photonics Lab
1 year
"Deformable microlaser force sensing" now out @LightSciAppl. Led by Elena @edalaka and Joe we show that #droplet #microlasers can measure absolute mechanical #forces inside cells, tumour spheroids, and in vivo! đź§µ.
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nature.com
Light: Science & Applications - Characterising forces deep inside biological tissue is a challenging task. Here, we demonstrate that deformable biointegrated microlasers can sense nanoscopic...
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@SchubertLab
Biointegrated Photonics Lab
1 year
One of the most inspiring conference I ever attended #Cardioascona! Grateful for the opportunity to present our work on #cardiac #sensing, including the latest force sensing approach (stay tuned for the paper!).
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@SchubertLab
Biointegrated Photonics Lab
1 year
RT @TitzeVera: My PhD thesis "Hyperspectral confocal imaging of whispering-gallery-mode microlasers for bio- and ecophotonic applications"….
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@SchubertLab
Biointegrated Photonics Lab
1 year
RT @TheAnnaFischer: Check out my first first-author publication on controlling lasing around exceptional points in coupled nanolasers publi….
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nature.com
npj Nanophotonics - Controlling lasing around exceptional points in coupled nanolasers
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@SchubertLab
Biointegrated Photonics Lab
1 year
Congratulations Vera! #PhDdone All the best for your next career step, we will miss you and are already looking out for more fantastic science from you.
@TitzeVera
Vera Marie Titze
1 year
Very excited to share that I have passed my PhD viva at @PhysAstroStAnd yesterday. A huge thanks goes to @sylvaingigan and @NanoStAndrews for an interesting and enjoyable discussion of my research and my thesis - and for staying around today to share some of their work with us!
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@SchubertLab
Biointegrated Photonics Lab
1 year
RT @JudithTTSu: Our work on ultra-high-Q free space coupling to microtoroid optical resonators has been published in @LightSciAppl. https:/….
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@SchubertLab
Biointegrated Photonics Lab
1 year
This is so cool! Amazing wireless #OLEDs from @TheGatherLab. Check it out 👇.
@TheGatherLab
GatherLab
1 year
Direct integration of #OLED on acoustic antenna leads to the world's smallest #wireless "light bulb". Paper now out in @ScienceMagazine Advances
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@SchubertLab
Biointegrated Photonics Lab
2 years
Finally out! A mega project led by @TitzeVera to develop the fastest #microlaser #spectrometer to date and compile ALL procedures we developed around laser #uptake, #singlecell experiments, and #data #analysis. Fantastic colab with @CECAD_ and @MPIAGE! 👉
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@TitzeVera
Vera Marie Titze
2 years
So excited to share our @NatureProtocols on integrating microscopic #lasers into living cells and recording lasing spectra through #hyperspectral confocal imaging. We share our full workflow for applications like cell tracking & intracellular sensingđź§µ .
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@SchubertLab
Biointegrated Photonics Lab
2 years
RT @TheGatherLab: Happy holidays from the Humboldt Centre for Nano- and Biophotonics @ChemUniCologne! Sharing here again our treasured #HCN….
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