Saskia Hogenhout
@SaskiaHogenhout
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Scientist at the John Innes Centre. Molecular Plant-Microbe-Insect Interactions. Loves travelling, reading and hiking.
Norwich, UK
Joined July 2013
Aphid effectors suppress plant immunity via recruiting defense proteins to processing bodies | Science Advances
science.org
Aphids hijack plant immunity via p-bodies, but plants fight back with a heat shock protein in an unexpected twist on defense.
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🎉 Thrilled to share our latest work, now published in @NewPhyt! 🌱 Aphid effector Mp10 fine-tunes plant immunity via EDS1, balancing suppression and activation of defence. 🧑🔬@gravino_matteo, @samtmugford, @SaskiaHogenhout et al., @JohnInnesCentre, @SapienzaFisVe #️⃣
Aphid effector Mp10 balances immune suppression and defence activation through EDS1-dependent modulation of plant DAMP responses Gravino et all. @samtmugford @gravino_matteo @SaskiaHogenhout 📖 https://t.co/jxMQAkn1Vs
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Great place to develop your independent career on #MPMI @IPMBSinica. We @AdamWu9527 @LaySunMa1 @KaWaiMa6 are here #2025ISMPMI. Welcome to talk to us to learn more about open #PI positions
📢 #AcademicJobs Tenure-track faculty positions in plant biology and plant-related microbiology Intramural funding, core facilities, generous startup, and a vibrant research environment at @IPMBSinica @AcadSinica #Taiwan
https://t.co/KlpSy2vMTI 🗓️ Deadline: Aug. 31, 2025
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A week of happy moments!!! Thank you ERC Thank you ERC
Yeah, livin' the raw deal, three-course meals, spaghetti, fettuccine, and veal 🎶
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#2025ISMPMI @Tolga_Bzkrt introduces the effector and immune processes occurring at Phytophthora haustoria. The helper NRC4 localises to haustoria and upon activation inserts itself into the extrahaustorial membrane forming punctuate foci. It seems activated NLRs beep annoyingly.
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Effector Innovation in Genome-Reduced Phytoplasmas and Other Host-Dependent Mollicutes | bioRxiv
biorxiv.org
Obligate host-associated bacteria with reduced genomes, such as phytoplasmas, face strong evolutionary constraints, including metabolic dependence on hosts, limited horizontal gene transfer (HGT),...
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I’ll advertise a fully funded PhD position soon, so watch this space! Also open to hosting candidates for PostDoc fellowships. If you're attending this year's @ISMPMI meeting in Cologne, let me know and we can meet up! 😀 2/2
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I just published: Mountains can meet: farming the desert with microbes, not fertilizers In the harsh deserts of Southern Algeria, Nadjette Djemouai is uncovering the power of native microbes to support sustainable agriculture. @GetGenome 🇩🇿 https://t.co/G5MvnKbcKE
kamounlab.medium.com
In the harsh deserts of southern Algeria, scientists like Nadjette Djemouai are uncovering the power of native microbes to support…
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The real China. The ‘wild’ writer who told the truth about work in China - https://t.co/fAaAvLqroY via @FT
ft.com
How a Beijing courier’s story struck a chord and escaped the censors
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Deeply honored and humbled by this recognition. Thrilled to be part of @TheSainsburyLab! None of this would be possible without the unwavering support from my colleagues, friends, family, and above all, every past and present member of my group! 🫶🏻🫶🏻🫶🏻🙏🙏🙏@royalsociety @ISMPMI
We are delighted to announce that TSL group leader, Professor Wenbo Ma @wenboEffector, has been elected a Fellow of the Royal Society. This honour celebrates her groundbreaking research in molecular plant pathology.
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I missed this one! Congratulations @VectorBioSpace ! More than deserved recognition! 💚 - can’t wait to see you later this year! 👏
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Congratulations Yufei! 👏👏👏
@Yufeili15 successfully defended her PhD. Congratulations! 🎉 Thanks to examiners @Team_Thomma @Phil_Carella and the @wenboEffector group
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This position may be filled at any time. If you're interested but haven't applied yet, we encourage you to submit your application this week!
*Please apply through TSL website. We will begin reviewing applications on March 24, 2025.
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I will be recruiting one PhD student and one postdoc in 2025. If interested please contact me already. @VIBLifeSciences 🌱🌱🌱We are interested in steroid hormones. See our published work PMID: 40068682 PMID: 38513023 PMID: 37639582 PMID: 37365405
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Therefore, we identified EDS1 as a key player in the dual role of Mp10, suppressing DTI/PTI responses and eliciting ETI, indicating that Mp10 operates at the interface of PTI/DTI and ETI to manipulate plant immunity.
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We are excited to share our latest preprint from the Hogenhout lab (@SaskiaHogenhout, @JohnInnesCentre) on plant-aphid interactions, showing that the aphid effector Mp10 balances suppression of DAMP responses and activation of ETI via EDS1.
Aphid effector Mp10 balances immune suppression and defence activation through EDS1-dependent modulation of plant DAMP responses https://t.co/Tu8Vy0Dl9H
#biorxiv_plants
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Fascinating insight into the biology of phytoplasma effectors and their induction of phyllody in plants using effectors such as SAP05– which also identified a completely new form of regulated proteolysis @SaskiaHogenhout @JohnInnesCentre @TheSainsburyLab #CMINorwich25
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