Sam Confederat
@SConfederat
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PhD single-entity nanoelectrochemistry @SENTINEL_ITN @universityleeds| Traveler | Nature lover
Joined August 2019
Inviting everyone to support my half marathon fundraising for Cancer Research UK!
fundraise.cancerresearchuk.org
Cancer is happening right now, which is why I’m raising money right now for Cancer Research UK. There’s no time to lose! Donate to my page today and help bring forward the day when all cancers are...
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Check out my first first author paper of my PhD out now in @natBME ! We utilize solid state #nanopore sensing and #dna #nanotech as a way to assay #CRISPR #Cas9 binding efficiency!
Sensing the DNA-mismatch tolerance of catalytically inactive Cas9 via barcoded DNA nanostructures in solid-state nanopores https://t.co/njx9i3y6Uh
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Single cell RNA-seq has changed our understanding of cellular heterogeneity but it only provides a snapshot at a fixed time point of the cell transcriptome... not any more !
biorxiv.org
Single-cell RNA sequencing has revolutionised our understanding of cellular heterogeneity, but whether using isolated cells or more recent spatial transcriptomics approaches, these methods require...
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Today marks the last day of our @SENTINEL_ITN. It's been a wonderful experience and this short poem here sums up my gratitude to everyone that made this ITN so enjoyable!
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Glad to see this work published! Brilliant collaborative work lead by @Fabio_Marcuccio @dsoulias @MEdwardsLab providing a mechanistic description of the enhanced sensitivity of a nanopore in 50% PEG...
Mechanistic Study of Conductance & Enhanced Single-Molecule Detection in a Polymer Electrolyte #Nanopore By Paolo Actis, Eric Hewitt, Martin Edwards et al @UniversityLeeds @paoloactis @UArkansas @EricHewittLeeds 🔓 Open access in ACS Nanoscience Au 👉 https://t.co/JDE5fWgk9e
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Our recently published review on the future of High-throughput Nanoelectrochemistry is out now! Great team effort
Our review/perspective @an_chem on the future of nanoelectrochemistry where AI/data science will be central! What a great team @xu_xiangdong @dvalavan @paolo_ciocci @SConfederat JF @FKanoufi @Patrick_Unwin.Thanks @SENTINEL_ITN @MSCActions for enabling it https://t.co/d4WmeawH34
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Last week a brilliant bunch submitted this invited review on high throughput nanoelectrochem https://t.co/0EvO09IMPH
https://t.co/jZFB4VFolw All credit to @FKanoufi @paoloactis @Patrick_Unwin @paolo_ciocci @SConfederat @Fabio_Marcuccio @xu_xiangdong @dvalavan @MSCActions #H2020
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Some DNA origami art display was appropriate for our wonderful conference venue at Prinsehof Museum👌#smps3
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Very grateful to attend this fantastic nanopore conference and to present some of my phd work! #smps3
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A Tweetorial about our recent work @acsnano on polymer-electrolyte nanopore. Super collaboration between @uarkfulbright @AstburyCentre @BraggRoyceLeeds brilliantly delivered by @Chalmazers @Fabio_Marcuccio @dsoulias
https://t.co/dGz2mAPv4z
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We demonstrate the characterisation and quantification of complex supramolecular nanostructures in a rapid and label-free manner, with further implications for the analysis and manipulation of a wider range of nanomaterial designs.
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In this study we explore a solid-state nanopore approach for high-throughput detection of higher-order DNA origami assemblies with single-molecule resolution.
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Our work on nanopore fingerprinting of supramolecular DNA origami nanostructures has been published in Biophysical Journal! Link to the paper: https://t.co/7x5BG6e5U7
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Sometimes I get the question about #OpenHardware: What's next? Building an NMR? Now the answer is YES!!!! Me and @JuliaRKrug are looking for a PhD for, well, building an Open NMR :D possibly with background in electronics/physics and happy to build stuff. #NMRchat and pls RT
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We have a research fellow position available to develop a single molecule biosensor platform based on nanopores and DNA origami
jobs.leeds.ac.uk
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What a team!!! we had a fantastic time in Rimini for our training week, thank you very much @ElementsSrl for the hospitality !!
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Amazing! Nanoscale #emoji! We are so proud of our work with @ResearchInSch and @RoyceInstitute, which is making advanced #materialsscience and nanoscale #engineering accessible and engaging for high school students. Lots of #smiles all round with this one! 😀 #inspiring
Wow! hese microscopic smiley faces - 100 bilionths of a metre in diam- are made from repurposed DNA! @AndrewJLee90 Students from St John Fisher Catholic Voluntary @sjfdewsbury & @TaptonSciRes will soon make them too. Possibly the youngest people to so. https://t.co/n63JUViXfm
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Super excited to visit for the first time our new @bionanoleeds home at @BraggRoyceLeeds! Can't wait to set everything up... @Fabio_Marcuccio @SConfederat @Chalmazers @ElenaManci @paoloactis @VirginiaPensab2 @EllenSlay @AgataSzuba @AnnaNano0
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I'm so happy that the efforts of my Ph.D. work are now published in eLife! I'm very grateful for an opportunity to work in such a stimulating environment with experts in different fields of biology and physics. @gijsjekoenderi1 @BertinAurlie2 @LabRichter @fouzia_bano
Online: in a team effort with Manos Mavrakis (Institut Fresnel Marseille), Aurelie Bertin (Institut Curie Paris) and Ralf Richter (Univ. of Leeds) we showed how septins, the enigmatic 4th cytoskeletal filament system, polymerize on lipid membranes: https://t.co/NaJ2srz1rB
@eLife
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Great work @V_Saggiomo I must say it goes well with our preferred Nespresso capsules in the office👌
Finally is out, our super cheap, easy to produce in millions, almost universal, and with low waste impact nucleic acid detection (LAMP test for #COVID19) non-instrumental device. The answer is: a Nespresso capsule. The question is: why we did this? 1/n https://t.co/ZHe9JHqUcy
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