Ryan Lab
@RyanLabTCD
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Official account of the Ryan Lab at @tcddublin #Memory #Engram #Development #Instinct
Dublin, Ireland
Joined January 2021
Cover article: our recent review in @TrendsNeuro on engram ensemble 'competition' as an experience-informed, and reversible, mechanism of forgetting.
Check out the October 2025 issue of Trends in Neurosciences: https://t.co/luVS5Ibg7s Cover article: ‘The cost of remembering: engram competition as a flexible mechanism of forgetting’ by Livia Autore, Michael Drew & Tomás Ryan @TJRyan_77
https://t.co/XsF9dCsoKs
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Junior or mid-career group leaders working in neuroscience, apply by 30 Jan to join the FENS-Kavli Network! We are looking for excellent and engaged future scholars, committed to exchanging scientific ideas & contributing to improve Neuroscience in Europe. https://t.co/vxsFdPIkfB
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Late breaking abstract at #SfN25 by @erikasstewart: LBP032.14 - Microglial plasticity across development mediates infantile amnesia (1 PM - 5 PM Sunday Nov 16). @SfNtweets @tcddublin @ListerInstitute
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Online now! Memory engram synapse 3D macromolecular architecture visualized by cryoCLEM-guided cryoET
cell.com
Memories are stored within subpopulations of cells termed “engrams” that are wired into a neuronal circuit via synapses, mediating plasticity. The in-tissue 3D macromolecular architecture of engram...
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📣 #MCCS25 starts TOMORROW! Check out our poster session tomorrow & our symposium on Friday to hear from the best and brightest in molecular and cellular cognition. More information here: https://t.co/MG06VRier2
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Don't miss talks from our selected speakers at #MCCS25! Come hear exciting research updates about all things neuroscience 🧠 There's still time to register! https://t.co/MG06VRier2
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Final agenda published on below website.
📢 The #MCCS25 abstract submission deadline has been EXTENDED! Trainees, get your abstracts in by October 20 to be selected as a speaker! More information and registration here: https://t.co/MG06VRhGBu 📍Note the poster location change!
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Sickness engrams modulate anticipatory immune responses https://t.co/YVAYYB0Mqb
biorxiv.org
A threat to survival in the wild is vulnerability to infection. The immune system is essential for defence against foreign species which cause sickness. During infection the brain triggers conserved...
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Meet the #MCCS25 speakers! Check out talks from Drs. @crezaval & Priya Rajasethupathy at our Symposium on November 14. Register now: https://t.co/MG06VRhGBu
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So happy to be on the October cover of @TrendsNeuro! 🎃
Check out the October 2025 issue of Trends in Neurosciences: https://t.co/luVS5Ibg7s Cover article: ‘The cost of remembering: engram competition as a flexible mechanism of forgetting’ by Livia Autore, Michael Drew & Tomás Ryan @TJRyan_77
https://t.co/XsF9dCsoKs
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Microglial plasticity across development mediates infantile amnesia | bioRxiv
biorxiv.org
Infantile amnesia, the inability to recall episodic memories formed during early childhood, is a hallmark of postnatal brain development. Yet the underlying mechanisms remain poorly understood. This...
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What's your earliest memory... and is it real? Start the week with this @bbcworldservice Crowd Science episode, featuring #ListerFellow Tomás Ryan @TJRyan_77
Do you remember when you were a baby? If so, scientists think those memories may not actually be real and that we can't remember the first few years of our lives - they it call infantile amnesia. But why does it happen? 🎧 https://t.co/6OVLjGV8zs
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Meet the #MCCS25 speakers! Don't miss talks from Drs. Satoshi Kida and @FrickKaryn on November 14. Register now: https://t.co/MG06VRhGBu
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📢 The #MCCS25 abstract submission deadline has been EXTENDED! Trainees, get your abstracts in by October 20 to be selected as a speaker! More information and registration here: https://t.co/MG06VRhGBu 📍Note the poster location change!
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Final version published in @PLOSBiology this week. Full tweeprint to follow in coming weeks. https://t.co/Em4FcRiNHK
journals.plos.org
How does the brain balance innate responses with adaptive learning when reacting to threats? This study shows that repeated exposure to looming stimuli reduces innate defensive responses via hippoc...
Our new paper in @PLOSBiology on how innate 'ingrams' show plasticity with experience, resulting in engrams that reversibly alter adaptive behavioral responses to predator related afffordances in the environment. https://t.co/Em4FcRjlxi
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Our new paper in @PLOSBiology on how innate 'ingrams' show plasticity with experience, resulting in engrams that reversibly alter adaptive behavioral responses to predator related afffordances in the environment. https://t.co/Em4FcRjlxi
journals.plos.org
How does the brain balance innate responses with adaptive learning when reacting to threats? This study shows that repeated exposure to looming stimuli reduces innate defensive responses via hippoc...
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Updated version: https://t.co/j47bFxRGdt
biorxiv.org
Animals rely on innate and learned behaviour to respond to their environment, but how the brain balances hardwired responses with adaptive flexibility remains unclear. Here, we demonstrate that...
Our new preprint on the experience dependent adaptation of the visual looming response instinct. Representing the PhD work of @paconway_. Also featuring @liviautore, @Andrea_MZamora, @Clrar, @jamesoleary. And with collaborators @brimmmers & @InAnOther
https://t.co/TU4JIuJR2G
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Join us in San Diego this November for #MCCS25, including 16 X research talks and the MCCS debate. Invited faculty speakers are announced below. Half of speakers will be selected from submitted abstracts. Registration is open:
📍 Register now for #MCCS25 on November 13 & 14! Join us for talks & networking with the best and brightest in molecular and cellular cognition. Check out the link for more information and to register & submit an abstract 👉 https://t.co/MG06VRier2
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Our new opinion piece is live now on TiNS! @TrendsNeuro huge thanks to @TJRyan_77 and Michael Drew for the great collaboration!
The cost of remembering: engram competition as a flexible mechanism of forgetting. Our new perspective piece in @TrendsNeuro, lead by @RyanLabTCD alumni, @liviautore. Also with Michael Drew from @UTAustin. Trends in Neurosciences
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🧠❄️ Memory of cold primes metabolic responses. #ListerFellow @TJRyan_77 talks about his breakthrough research into "cold engrams," interoception and so-called predictive physiology. 📖 Discover this "cool" research: https://t.co/Ltq8UIOOhZ
@tcddublin @lynchielydia
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