RuijterLab
@RuijterLab
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Dedicated to the development of creative methods for the synthesis of complex molecules
Amsterdam, The Netherlands
Joined March 2021
RT @THansenChem: Woke up at 5:45 this morning😴, but it was totally worth it!😊 Had a blast sharing some sugar-sweet chemistry at the @HRSMC….
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RT @TomNGrossmann: Now as early view @angew_chem: Structure-Based Design of Bicyclic Helical Peptides That Target the Oncogene β-Catenin ht….
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RT @TomNGrossmann: Out now @angew_chem: Structure-Based Design of Bicyclic Helical Peptides That Target the Oncogene β-Catenin https://t.co….
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RT @CeliaFGuerra: @PascalVermeeren wins KNCV-CTC Thesis Award🏆! Well done Pascal! 🎉 @KNCVchemie @VU_TheoCheM @VU_Science. .
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The final version is now out in @ChemEurJ Early View!.Read it here:.
Do you think the Ugi multicomponent reaction:.- is only useful for boring small molecules?.- does not work with hindered ketimines?.- has poor diastereoselectivity?.Then read our latest work (Open Access!), just out as Acceped Article in @ChemEurJ:
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RT @In_Seino: Are you coming to the 2024 Dutch Peptide Symposium, May 31 at VU Amsterdam O2 auditorium? We have some exciting invited speak….
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Our recent paper in @ChemEurJ on iron-catalyzed carbene transfer to isocyanides attracted significant attention from the chemistry community and is now a #TopDownloadedArticle!.Read it yourself (Open Access!):
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RT @TomNGrossmann: Now online: Transcription factor-targeting stapled peptides @ChemBioChem. We've captured 2 peptide confirmations with cr….
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The reaction proceeds with complete diastereoselectivity. DFT studies not only provided insight in the origin of stereoselectivity, but also showed that the reaction proceeds through a hydrogen bonding mechanism, resembling the accepted mechanism of the Passerini reaction.
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We use an intermediate from our recent total synthesis of monoterpene indole alkaloids as the imine input in a three-component Ugi reaction to gain rapid access to diverse, highly functionalized 'synthetic alkaloids'. @brendan_horst @THansenChem.
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Do you think the Ugi multicomponent reaction:.- is only useful for boring small molecules?.- does not work with hindered ketimines?.- has poor diastereoselectivity?.Then read our latest work (Open Access!), just out as Acceped Article in @ChemEurJ:
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Petasis three-component reaction without the classic restriction on the aldehyde input: great work! The scope of accessible branched tertiary amines is amazing!.
Now you can Petasis (virtually) any borons! Super simple and powerful method to prep fully-sp3 complex amines is now on @ChemRxiv as our collaborative work with @QinLab. Congrats on everyone's accomplishment! @JetTsien @SijieChen17 @rohanmerchant1 .
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RT @TrevorAHamlin: Very proud of this work! 🔥 .In 2021, our work on understanding H2 activation by metallylenes appeared in @ChemicalScienc….
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Less than a week left until the Early Bird deadline, so register now for the 2024 Dutch Symposium on Organic Chemistry!.Also, note a small update in our speaker line-up (see flyer). Register here: More info:
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RT @ChemicalScience: Don't miss F. Matthias Bickelhaupt's et al.'s recent article - it's one of this week's #ChemSciCovers. Nature and stre….
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Join us in Lunteren at the biannual Dutch Symposium on Organic Chemistry - April 4-5, 2024!.@soc_kncv invites you to two days of exciting developments in organic chemistry!.Register here: More info:
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RT @NoelGroupUvA: We're absolutely thrilled that our robotic platform, #RoboChem, has been published in @ScienceMagazine!. 🔗.
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RT @THansenChem: One way or another!🍎↔️🍐 We explain in our new @JOC_OL how minimal changes in the donor impact the formation of different r….
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RT @VU_TheoCheM: Our #OpenAccess paper on the Blueshift in Trifurcated Hydrogen Bonds was featured on the cover of @ChemPhysChem! 🔥 . Cover….
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