Hesper Rego
@Rego_Lab
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Just a girl standing in front of a microscope asking it to take lots and lots of data. Torturing bacteria in the Rego Lab @YaleMed. she/her/hers
New Haven, CT
Joined March 2018
Faculty Search Webinar! Curious about the @YaleMicroPath faculty search and life in CT? Please join us for a Q&A webinar 9/19/24 12pm noon EST. Panelists @Rego_Lab, @HoLabHIV, @Goodman_lab, and Craig Roy. Participation is anonymous. Registration required:
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Faculty search! @YaleMicroPath is looking to hire assistant professor(s) focused on the pathogenesis of viral, bacterial, parasitic, or fungal infections. Info: https://t.co/bUb0Boc23C. Q&A webinar in Sept. Please RT!
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MmpL3, Wag31 and PlrA are involved in coordinating polar growth with peptidoglycan metabolism and nutrient availability https://t.co/lwFRqvZf9X
#biorxiv_micrbio
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Another paper from the lab. The now Dr. Ng, @weilynnng , describes how the nucleoid associated protein, Lsr2, helps promote chromosomal mutagenesis in mycobacteria.
journals.asm.org
Unlike many other pathogens, Mycobacterium tuberculosis has limited ability for horizontal gene transfer, a major mechanism for developing antibiotic resistance. Thus, the mechanisms that facilitate...
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This led to several surprising insights about the metabolism of mycobacteria at the single cell level. Specifically we show that the complexes that perform OXPHOS are spatially segregated from those that grow the bacterium. And metabolism changes as individual mycobacteria age.
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Really excited about this work from the lab. @celenagwin, together with @Kuldeep_R_Gupta, worked to understand how mycobacteria create heterogeneity in growth.
biorxiv.org
Individual cells within clonal populations of mycobacteria vary in size, growth rate, and antibiotic susceptibility. Heterogeneity is, in part, determined by LamA, a protein found exclusively in...
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Curious about the @YaleMicroPath faculty search? Please join on 9/18/23 at 12 noon EST for a Q&A webinar with @HoLabHIV @Rego_Lab @wmothes @Goodman_lab. Attendance and questions are anonymous. Details on department website. Register here: https://t.co/sKilGj2aiP. Please RT!
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Awesome opportunity to work with a great person!
Please RT! We are recruiting! Grant-funded positions to look at a) TB vaccine candidate development and b) TB antibiotic tolerance. Two SRA positions (links in next tweet). Ideal candidate will be curious, hard-working and fun to collaborate with. Full training provided.
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Studying a protein of unknown function is not for the faint of heart. We had many misdirections along the way, and there is still much to discover. Most importantly, we had loads of help from amazing collaborators: @ymoritalab, @JunLiuLab, and Ben Swarts' lab at CMU.
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@Kuldeep_R_Gupta, working together with @celenagwin, discovered that a protein of unknown function in mycobacteria (PgfA) is recruited to one side of the cell by our favorite protein LamA, where it coordinates lipid trafficking and fast polar growth
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Really excited and proud of this work out of our lab. https://t.co/jOSqkCOowe.
elifesciences.org
Asymmetric growth in mycobacteria requires a protein that is involved in trafficking mycolic acids to the outer membrane.
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1/9. There has been a ton of discussion on academic Twitter about reasons to leave academia. This thread is for young scientists who want to stay in academia. Let me first comment on the things I agree with from the “time to leave” tweets:
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Interested in tuberculosis? We have postdoctoral positions available. We study immunology, vaccines and host-pathogen interactions. Great group of people! Great city! Email or DM me.
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Yale Microbial Sciences Institute is proud to be a sponsor of #BlackInMicro week. Information at @BlackinMicro and online at
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Yale Microbial Sciences Institute - faculty position extended to all levels! Assistant Professor: https://t.co/XkPUmY4Y52. Associate or Full Professor: https://t.co/7Smnwisqmj. Partnership with @YaleMed Physiology, @YaleGenetics, @YaleIBIO, and @YaleMicroPath. Please RT.
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Assistant Professor search at the Yale Microbial Sciences Institute! More info here: https://t.co/XkPUmY4Y52. Women, persons with disabilities, and members of underrepresented minority groups: please apply. Assoc/full prof search coming soon. Please RT.
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I'm not very active on the Twitter. But this worked better than I had ever hoped. Thank you all for helping to spread the word!
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