Ralph Stadhouders
@R_Stadhouders
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Biologist studying gene regulation in immune cells 🔬Associate Professor @ErasmusMC
Rotterdam, The Netherlands
Joined September 2016
As promised a short 🧵 on our latest work just out in @SciImmunology! Spearheaded by talented PhD student Anne Onrust and Hi-C wizard @G_Stik 💪 What did we find? A central theme in my lab is understanding immunological memory in T lymphocytes. After a naive T cell has been 1/
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RT @jakescottMD: The aluminum question: why the route of exposure matters less than you might think. Aluminum in vaccines worries a lot of….
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RT @brainaddiction: It's clear that many do not understand what @NIH-funded research does to improve health. It's time to revive a study pu….
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RT @DrShrutiNaik: HEK293 cells are an immortal ( forever living) cells from an embryonic kidney made in 1973. These immortal cells (not fet….
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RT @SamuelBHume: Top 5 advances in medicine this week (🧵). 1. AI-designed snake anti-venoms. These inhibit the 'three-finger toxins' that m….
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RT @zanehkoch: WHY DOES THE EPIGENETIC CLOCK TICK?. While money has been poured into developing therapies to reverse the epigenetic clock (….
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RT @bart_lambrecht: Happy new year, this paper just made it for 2024. Thanks to hard efforts of all in the lab. A new way to select clone….
elifesciences.org
Rationalized selection of responsive TCR clones by single-cell analysis to aid in the generation of novel TCR transgenic animals.
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RT @Aiims1742: Which are the highest cited original research publications in #PancreaticCancer over the past five years (from 2020 to 2024….
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RT @SGRodriques: One of the remarkable things for me about NeurIPS this year was how quickly the entire AI for Biology community has gone a….
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RT @Anders_S_Hansen: Our preprint by @DomenicNarducci and the companion preprint by @deWitLab are now out in @MolecularCell . ZNF143 is not….
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RT @SamuelBHume: 2024's top 10 advances in medicine (🧵). 1. The numerous benefits of GLP1R agonists. As well as causing weight loss, GLP1s….
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RT @SamuelBHume: Biggest medical discoveries of the week (🧵) . 1/8 . Treating pre-eclampsia by sprouting new blood vessels . Delivering VEG….
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RT @KexinHuang5: 🧬GWAS is fundamental in drug discovery, linking disease to genetic variants. However, studying rare and uncommon diseases….
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RT @BodenmillerLab: It's wonderful to see that spatial proteomics has been recognized as Nature Methods' Method of the Year 2024. https://t….
nature.com
Nature Methods - Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in...
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RT @AlastairMcA30: Trump says RFK Jr will “investigate” the link between vaccines and autisms as “somebody needs to find out.”. We’ve ALREA….
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RT @seagertp: If the structural similarity between hemoglobin and chlorophyll doesn't fascinate you, then I'm not sure we can be friends. h….
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RT @SamuelBHume: 5 big medical advances from November (🧵). 1. Diabetes prevention. In obese adults, Tirzepatide (a GLP1/GIP receptor agonis….
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RT @dlcvdberg: New preprint from the lab where we show how dysregulated transcription elongation causes neurodevelopmental defects. Immense….
biorxiv.org
Transcription pause-release constitutes a key step in the regulation of gene expression. Pathogenic variants in various pausing regulators have been identified in neurodevelopmental disorders, but...
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RT @SamuelBHume: Biggest medical discoveries of the week (🧵). 1/8. A twice-yearly prophylactic injection - Lenacapavir - is >95% effective….
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RT @koeng101: For storage, I’m freeze drying most of my cells rather than storing in a -80c. Can have em at room temperature with full stab….
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