Engineers at @nyutandon & @Perlmutter_CC have published a review on human cancer-on-chip platforms used to model the tumor microenvironment. They also explore what’s next for developing next-gen systems to advance precision cancer medicine. Read more:

Read our summary of new and updated @OECD in vitro and in chemico test guidelines on a variety of topics, including eye irritation, skin sensitisation, immunotoxicity, and more:

Following the announcement of @NIH's new initiative to expand human-based science and reduce animal use in biomedical research, Thomas Hartung of @jhucaat urges the global research community to follow suit. Read his full commentary here:

We are ecstatic to announce that we have just committed another million pounds to life-saving medical research using entirely animal-free methods! 🎉. We may be a small charity - but we're having a big impact. #SmallCharityWeek

New organoid atlases, part of the @humancellatlas, allow scientists to compare cells across labs, methods, and patient samples (past, present, and future), better match organoids to human development, and improve their design. From @IHB_Research:.

Is your lab not yet set up for microfabrication? Have no fear. The @GleghornLab at @udbme has developed a new modular, reusable, and perfusion-ready microphysiological platform adapted to diverse organ systems. Preprint by @DanJMinahan et al.

Instead of subjecting animals to controlled cortical impact, weight-drop, and fluid percussion injuries, scientists at @JHUAPL & @jhucaat are using human brain organoids to study traumatic brain injury.

📢 Must-have tool for researchers, grant reviewers, & IACUC members. 💡 @ReplAnimalRes's "Replacement Checklist" helps evaluate whether all possible alternatives to animal use in research have been properly considered. Here's why it works 🧵

Acuerdo político en Europa para la eliminación gradual de las pruebas con animales. @Act4AnimalsEU .