I&I PhD platform
@PhdPlatform
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Phd platform for the Infection & Immunity PhD program in Utrecht. #IIPhDPlatform
Utrecht
Joined October 2019
The IgA response to microbiota in IBD-patients may uncover disease-modifying microorganisms and reveal improved biomarkers of disease progression, concludes @marceldezoete at @UMCUtrecht in a study by Dutch and American investigators in @CellHostMicrobe
https://t.co/AB5Bsr9rRN
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#OnThisDay, 10 Feb 1917, plant pathologist Johanna Westerdijk becomes the first female professor in the Netherlands when she is appointed at @UniUtrecht
#WomenInSTEM #STEMfem #OTD #WaybackWednesday
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Have a look at our latest #acceptedpaper on #lymphocytes #turnover after #SCT using #deuteriumlabeling and #mathematicalmodeling! @CTI_UMCUtrecht
#publication #research #Tcells #Bcells #homeostasis
https://t.co/KUDjTEdsXQ
@eLife
elifesciences.org
Altered lymphocyte dynamics after hematopoietic stem cell transplantation cannot solely be explained by low lymphocyte numbers.
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Beautiful work! @IlievLab @CellCellPress Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies: Cell
cell.com
Doron et al. present evidence that commensal fungi in the human gut shape antibody responses in the blood to protect the host from systemic lethal fungal infections. The innate immunity regulator...
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Our manuscript on the dissemination of E. faecium vanA resistance in Dutch hospitals is now published in Genome Medicine! https://t.co/A0s1ShE1l3 Interested in clonal vs plasmid/transposon dissemination? Check our work! Thanks to @AnitaSchurch for leading this project
link.springer.com
Genome Medicine - Enterococcus faecium is a commensal of the gastrointestinal tract of animals and humans but also a causative agent of hospital-acquired infections. Resistance against...
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https://t.co/gsvRoS7eYM launch: Want to apply mass cytometry to your research project? Learn all about it in next week's kick-off seminar in collaboration with Fluidigm (Jan 21, 11:00 CET). @fluidigm @UMCU_CMM @UMCU_Intl @cancercenterumc #cytof
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and @wvschaik and me had the opportunity to write a perspective on this. The takeaway message? Be cautious in the use of colistin, for resistance can arise relatively easily. https://t.co/n1aBKVOFoR
journals.plos.org
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Cool and important paper out from Malmstrom labs (Lund University) where they elucidated the structural details of StrepA M1 interaction with human IgG. Important for rational M-based vaccine design https://t.co/9dQzX7QVgR
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Great to see that mlplasmids https://t.co/9TFNqaxQyS is a useful resource for the community. Will read in detail the manuscript @SamLipworth, congrats! :)
Finally we tried to look at the plasmidome using @Sergi_Arredondo MLPlasmids - we found signal of a diverse plasmidome even in isolates which are closely related at the core genome level. Replicons appeared to be largely genus restricted, though there was some overlap...
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Really nice to have this paper out and highlighted by @ASMicrobiology! Want to know about the evolution and impact of colistin resistance in Klebsiella? Read on 👇!
K. pneumoniae strains can develop colistin resistance through many evolutionary trajectories once exposed to colistin. This includes single nucleotide polymorphisms, insertions and deletions, and the integration of insertion sequence elements. #AACJournal
https://t.co/u36tNeH8dE
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Proud to present research by our PhD student Roos Berbers, published @FrontImmunol ( https://t.co/4q5hfvMQCK). Read about how Low IgA Associated With Oropharyngeal Microbiota Changes and Lung Disease in Primary Antibody Deficiency. #immunology #CVID @UMCUtrecht @PhdPlatform
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Please join me in congratulating Suzan Rooijakkers, professor of microbiology @UMCUtrecht, who received today a € 2M Consolidator Grant from @ERC_Research to identify antibodies that use the immune system to fight E. coli infections https://t.co/gxCBl5NPsE
@MarcBonten #ERCCoG
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Really happy that our article on #longitudinal sequencing of #TCR #repertoires from #scleroderma is now online. Congrats to all the co-authors. @CTI_UMCUtrecht @UMCURRCI @IenI_UMCUtrecht
#bioinformatics #rheumatology
@airr_community @iRecRepPapers
https://t.co/dgsDz1PC3v
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Inhibiting the immune system can impede cancer treatment, how is still largely unclear. In a perspective for @NatRevImmunol @LindeMeyaard introduces a framework to classify different immune receptors which control the response: https://t.co/ZsDjZLkutb
@UMCUtrecht @YaleMed
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Lock down did not just bring down COVID cases but also invasive bacterial infections such as pneumococcal and meningococcal disease around the globe. Beautiful collaboration of the IRIS consortium now in writing on MedRxiv:
medrxiv.org
Background Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis are leading causes of invasive diseases including bacteraemic pneumonia and meningitis, and of secondary...
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We are looking for a post doc in immunotherapy!
academictransfer.com
Post-Doc on a project on the working mechanism of therapeutic IgA in oncology. Within the Immunotherapy group, you will unravel the modes of action of IgA in vitro and in vivo.
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How every PhD students feels in the last months before submission [source; from Dutch television (Nieuwsuur)] - I don't enjoy writing but to have written. - I feel amazing once I'm done. - The process itself is torture. #PhDLife
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