Peng Jiang
@PengJiang20
Followers
492
Following
72
Media
2
Statuses
42
NIH Stadtman Investigator @ NCI Cancer Data Science Lab All views are my own and do not represent NIH/NCI.
Bethesda, MD
Joined July 2019
A new Cell paper is online from brilliant CDSLers! This paper presents the Cancer Immunology Data Engine (CIDE) framework, broadly applicable to #CancerResearch and #Oncology. AOAH is featured as a promising new #Immunotherapy. https://t.co/c4Ku3DUGy1
0
12
43
Our Cell paper is online ( https://t.co/t5bOxlCN8q)! We present the CIDE framework, broadly applicable to cancer research and oncology. Also, we highlight AOAH as a promising new immunotherapy.
3
8
20
Our paper "A SSIM Guided cGAN Architecture For Clinically Driven Generative Image Synthesis of Multiplexed Spatial Proteomics Channels" has been accepted at the IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology! https://t.co/hiepH7XJYD
linkedin.com
Our paper "A SSIM Guided cGAN Architecture For Clinically Driven Generative Image Synthesis of Multiplexed Spatial Proteomics Channels" has been accepted at the IEEE Conference on Computational...
2
2
14
With a mixed bag of emotions - nervousness, excitement, fear & determination, I am announcing the start of my lab at @sbpdiscovery, San Diego. Our focus will be to develop new preventative therapies for cancer using machine learning.
18
24
107
Recently published: @bei2ru @PengJiang20 @NCIEytanRuppin develop Spatial Cellular Estimator for Tumors (SpaCET) to infer cell types and ligand-receptor interactions from #SpatialTranscriptomics data in cancer #CancerResearch @natrescancer
https://t.co/swplfEXITu
0
11
18
We have released the SpaCET package for cell lineage deconvolution and cell-cell interaction inference in Tumor Spatial Transcriptomics: https://t.co/5R7aYMMinR Welcome to try our package: https://t.co/SwcmEjzZre Congratulations to Dr. Beibei Ru and Dr. Jinlin Huang.
github.com
Spatial Cellular Estimator for Tumors. Contribute to data2intelligence/SpaCET development by creating an account on GitHub.
3
25
91
Interested in aging and cancer. I did a year of literature survey on this. Here is my list of 20 key open questions and challenges to better understand the interplay between aging and cancer. A thread 🧵👇
3
73
355
Advertise a half-day symposium on Gene & Cell Therapy by the Chinese Biopharm Association.
2
2
9
NEW content online! Big data in basic and translational cancer research https://t.co/X2lucO50th
1
97
224
Our review paper on Big data applications in Cancer is online at Nature Reviews Cancer @NatureRevCancer: https://t.co/neApGUR6Xe. reflecting joint insights from our colleagues (@NCIEytanRuppin @NCIKenAldape @hannenhalli @cenksahinalp @Sanjusinha7)
0
14
50
Why high tumor mutation burden is only predictive of immunotherapy response in some cancer types? We answer this question in our latest publication below and are excited to share it here. A🧵of 🏄♀️ below. https://t.co/4nHyM5famQ
4
143
520
Dear All, my branch Chief Eytan @NCIEytanRuppin and Chief of Pathology @NCIKenAldape, and I are co-recruiting a wet-lab Postdoc on Cancer Spatial and Functional Genomics.
0
13
24
Dear All, My Lab has a postdoc position available in Bioinformatics and Cancer Data Sciences. I would sincerely appreciate it if you can forward the following advertisement to young talents:
0
47
49
Thank you to Cancer Discovery @CD_AACR for highlighting our recent work. https://t.co/1rpGuO5u7E
1
2
18
Gene signatures associated with T cell resilience to tumor-derived immunosuppressive signals predict responses to immune checkpoint inhibitors and adoptive cell therapy, and identify FIBP as a negative regulator of T cell activity @PengJiang20 @theNCI
nature.com
Nature Medicine - Gene signatures associated with T cell resilience to tumor-derived immunosuppressive signals predict responses to immune-checkpoint inhibitors and adoptive cell therapy and...
0
6
27
We are very excited to release our Tres framework to evaluate T-cell anti-tumor efficacy, and FIBP as a candidate immunotherapy target. The paper is published on Nature Medicine: https://t.co/mCLCIEwdcY The Tres server is available at:
nature.com
Nature Medicine - Gene signatures associated with T cell resilience to tumor-derived immunosuppressive signals predict responses to immune-checkpoint inhibitors and adoptive cell therapy and...
7
37
134
A common way to ruin your project is to skip doing a series of pilots before the big expensive experiment. Pilots help you work out the problems and prevent the creation of impossible-to-analyze datasets. Published papers often don't discuss pilots, encouraging us to do the same.
7
59
565
Discover immunotherapy biomarkers from single-cell cytometry data: https://t.co/FgxFzpyg69 A short preview article we wrote to highlight a recent publication and briefly summary the relevant literature.
cell.com
Currently, identifying novel biomarkers remains a crucial need for cancer immunotherapy. By leveraging single-cell cytometry data, Greene et al. developed an interpretable machine learning method,...
1
6
11
Measure success by the joy you get from your work and that what you publish is true!
"I think success is having a career where you enjoy it so much that you almost feel guilty that people pay you to do it because you are having so much fun every day." Wise words by our 2019 medicine laureate William Kaelin who turns 64 today. #NobelPrize
1
32
90
Excited to share our study published by the BMJ today, which finds a gradual increase in the risk of covid-19 infection from 90 days after receiving a second dose of the Pfizer-BioNTech vaccine. @bmj_latest 1/8
bmj.com
Objectives To determine whether time elapsed since the second injection of the Pfizer-BioNTech BNT162b2 mRNA vaccine was significantly associated with the risk of covid-19 infection after vaccination...
5
15
39