Dr. Armstrong and his team at OMF’s Melbourne ME/CFS Collaboration are investigating the link between neuroinflammation, cerebral blood flow, and dysregulated hormones in #MECFS, #POTS, and #LongCOVID. Learn more about this study:

OMF’s Collaborative Center at Montreal, directed by Dr. Alain Moreau, published a paper on their study looking at SMPDL3B as a biomarker and potential therapeutic target in a subset of people with #MECFS. 👉 Read the paper summary:

🚗 Support OMF research by donating any unwanted vehicles taking up space at home. Cars, trucks, SUVs—even farm equipment—can help accelerate our work to end #MECFS and #LongCOVID. Donating is easy, and pick-up is free. ✨.👉

RT @Annakwood: Just signed up.

OMF StudyME is a free global recruitment tool that connects individuals interested in participating in research studies with the researchers conducting them. Sign up to help accelerate research into #MECFS and #LongCOVID 👉

RT @BatemanHorne: Let’s talk about the push–crash cycle. Exceeding your energy limits can lead to a crash and a flare in symptoms. How do Y….

🧬What is an IRB or Ethics Board? . Ethics review boards protect human subjects in research by ensuring that the information collected from them is necessary, that procedures done are safe, and that participants give informed consent. Learn more👉

Update: Patient-Reported Treatment Outcomes in #MECFS and #LongCOVID. After undergoing the peer-review process, the manuscript was today published in PNAS. Read the full publication 👉 🔗 Summary:

Happy 4th of July from Open Medicine Foundation! 🎆. Today we celebrate freedom, resilience, and unity—values that guide our work to bring hope to those living with #MECFS and #LongCOVID. Wishing everyone a safe and peaceful day! 💙

Some people also show altered electron transport chain activity (or mitochondrial function), which would have important implications in clinical management of the disease if the finding is supported moving forward.

Preliminary analysis of baseline muscle biopsy samples indicates that #pwME have a reduced mitochondrial biomass, roughly correlating to the number of mitochondria.

Dr. Systrom, the Director of The Ronald G. Tompkins Harvard ME/CFS Collaboration, and his team are studying the relationship between poor oxygen extraction, vascular abnormalities, and mitochondrial dysfunction and how they might relate to post-exertional malaise (PEM).

🎥 Video Update: A Muscle Biopsy Study to Understand the Molecular Mechanisms of #PEM . 👉 Watch the interview and learn more about this study:

Cytokines are small molecules produced by a number of cells, including immune cells, in response to external stimuli. Read more about cytokines and OMF's large-scale biomarker study, BioQuest:

📍A special moment from last week: OMF Founder and CEO Linda Tannenbaum visited OMF’s Collaborative Research Center at Montreal, directed by Dr. Alain Moreau. 👉 Learn more about OMF’s Collaborative Center at Montreal:

Dr. Chris Armstrong presents a detailed overview of a key area of investigation: how #pwME may rely more heavily on amino acids to produce energy, especially when the usual energy sources like fats and sugars aren’t being used efficiently. 🔗Watch now:

New Publication: OMF’s computation team identified metabolic pathways that are dysregulated in #MECFS & #LongCOVID. They also identified a combination of L-ornithine and L-aspartate (LOLA) as a potential treatment to explore in future clinical trials.

RT @PhillyPhile215: Reminder #pwLC #pwME #NEISVoid you can get your own Symptom Surfers shirt, different styles for different conditions. C….

RT @lifeanalytics: 1/ Delighted to be listed among this team for this paper, which is now published. I would like to Thank Dr Wenzhong Xiao….

An OMF-supported initiative at the @BatemanHorne, the Medical Education Resource Center (MERC), is working to educate doctors on how to diagnose ME/CFS and other multi-system chronic complex diseases. Read more about this initiative 👉

As of October, 2023, ICD-10-CM has a code for ME/CFS, though it’s important to keep in mind that using that code still requires a doctor to understand how to diagnose ME/CFS.