Nicole Grogan Fleege, MD
@NicoleFleege
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Breast oncologist @uihealthcare. Supportive oncology research. Alum @uiowa @iowamed @IntMedatIowa @IM_iowa @UMHemOncFellows.
Ann Arbor, MI
Joined September 2020
Important to point out that the KATHERINE and DB-05 populations are very different. - KATHERINE: any residual invasive dz - DB05: inoperable or node-positive residual dz (very high risk) In the future, we will have TWO SoC adjuvant treatments for RD, depending on risk
#ESMO25 💥DESTINY-Breast05 💥 T-DXd vs T-DM1 in residual high-risk HER2+ early BC: ✅️IDFS: 6.2 % vs 12.5 % → HR 0.47 ILD: 9.6 % (2 G5) vs 1.6 %! 💬 T-DXd substantially lowered recurrence risk vs T-DM1 — likely the new post-neoadjuvant standard. Full data eagerly awaited
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@NicoleFleege We are so grateful to you, Dr. Fleege, and all of the Featured Voices for spending your time with us at #ASCOQLTY25! We couldn’t do it without you – your experience and expertise put the science into perspective and context for your colleagues and our entire audience.
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Truly, @fumikochino, @RyanNipp, @crisbergerot et al are research giants, BUT they’re also approachable, supportive and SO much fun! Don’t be afraid to meet your research heroes in real life 🤣 & don’t let that tiny little voice ever stop you. Cant wait for #ASCOQLTY26!
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As I sit back and reflect on @ASCO #ASCOQLTY25, I think one of my biggest takeaways is to kick the imposter syndrome to the curve! I had the BEST weekend, & if I had let that little voice telling me I’m “not impt enough” to be a #FeaturedVoice, I would have missed out on so much!
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Day 1 Highlights from ASCO Quality Care Symposium 2025 https://t.co/BHzEMmFZnw
@ASCO @NicoleFleege @RyanNipp @anhbl9 @Sai_Wannaphut @ipreeshagul @fumikochino @lungoncdoc @QasimHussainiMD @ZouinaS @JasmineKambojMD
#Cancer #Medicine #Health #Oncology #OncoDaily #ASCOQLTY25
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That’s a wrap on #ASCOQLTY25! 🎬 Massive thanks to @ASCO for allowing me to be a #FeaturedVoice. I was in great company & hope I amplified the impt research presented this year! Congrats to all the presenters - your work is truly inspiring. Time to start the ⏰ on #ASCOQLTY26!
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It was an honor to represent @UCSFMedicine, @vkprasadlab at the national level and present our work (co-led with @Timothee_MD) at @ASCO's #ASCOQLTY25. Read more about it here: https://t.co/v34JxVKW77. Thank you to the organizers @fumikochino & co for highlighting our work. An
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Funding cancer research from 4⃣diverse perspectives: a @ASCO #ASCOQLTY25 discussion featuring panelists: 🫶 Philanthropy/Development @DrKarenKnudsen 🧑💻 Start up @yzafar 👨🔬 Industry @NealMeropol 🌍 International @LGutnik
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LAST @ASCO #ASCOQLTY25 panel! Never Let a Crisis Go to Waste: Funding Cancer Research in a Time of Rapid Change with panelists Drs @DrKarenKnudsen @yzafar @NealMeropol @LGutnik how can we sustain funding to continue to innovate & cure? Moderators @DrLolaFayanju @chandlercortina
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Dr @benderjack discusses #ASCOQLTY25 @ASCO abstracts and highlights the promise of (and difficulties with designing and implementing) #digitalHealth to improve cancer outcomes
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Dr @dlage @MSKCancerCenter #ASCOQLTY25 @ASCO: A RCT finds a telehealth visit shortly after hospital discharge did NOT appear to ⬆️ patient activation or ⬇️ sx burden & did not ⬇️ hospitalizations. This was a well done negative trial; seeing people sooner likely isn't enough. 🏥
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Dr. Smith describes outcomes from use of Cancer Distress Coach app + stepped care to optimize PTSD sx management after stem cell transplant: 🚨⬇️ PTSD sxs at 3 mos 🚨Sustained results at 6 mos Digital health approach for PTSD is effective for cancer survivors👏🏻 #ASCOQLTY25
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#ASCOQLTY25 @DrKedarKirtane @ASCO discussing why federal funding matters. Funding for clinical trials (like for supportive treatments & navigation) work to advance essential cancer outcomes like quality of life & survival. These innovative gains are at risk with slashed funding.
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While CONTINUUM did not ⬇️ pt sxs or hospital transmission rates for pts w/ advanced cancer, @dlage highlights the importance of continued research for this high risk population. 👏🏻 Great work from my former co-grantee, supported by @ConquerCancerFd & Rising Tide. #ASCOQLTY25
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‼️ #ASCOQLTY25 simultaneous publication by Budhu, et al: Screened But Still Struggling: Challenges in Delivering Financial Assistance After Positive Financial Toxicity Screens: https://t.co/134bFFIAfP
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Maya Elhage tells us about NDURE, an enhanced navigation-based intervention in head & neck cancer. NDURE led to:⬆️ preop consult w/ rad onc,⬆️ preop dental eval, &timely postop rad onc eval and planning. Mediated by ⬆️ performance of a care delivery process bundle #ASCOQLTY25
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#ASCOQLTY25 findings demonstrate federally funded cancer clinical trials help ensure essential areas of cancer care–early-phase research, multimodality Tx, dose de-escalation trials, rare & ped cancers–continue to be studied: https://t.co/VUbUdGeTrH
#SaveResearchStopCancer
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At #ASCOQLTY25, Krista Chen (star med student @HopkinsMedicine) presented the latest from our team on oncology provider perspectives of legal barriers in cancer care. This is our 4th major study in our series on patient legal vulnerabilities, together, these projects are helping
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📣Oral Abstract Session B starting now in Great Lakes Ballroom We’re about to hear research on topics from a telehealth intervention post-discharge to a digital health approach to improving PTSD to the role of federal sponsorship in clinical trials! Get here asap! #ASCOQLTY25
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A moment to congratulate the work of this program committee 👏🏻 With sessions at @ASCO #ASCOQLTY25 ranging from “what keeps leadership up at night” to “maintaining cancer care during catastrophic events” to all of the science in between. What. A. Program! 10/10, no notes.📝
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