Dr. Laura Jonkman
@NeuroLaura
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Neuroscientist (Ass. Prof) studying the pathological sensitivity of MR images in neurodegenerative disease (AD/PD). Also loves teaching, and penguins.
Amsterdam
Joined July 2010
There is still time to register for our upcoming webinar. Everything on postmortem imaging, this Thursday (Nov 6)! Sign up here:
Interested in postmortem imaging? Join us at the next webinar, where latest advances of postmortem imaging in ADRD will be discussed! Speakers: @NeuroLaura & Pulkit Khandelwal Panel: @DadarMahsa & @paul_yushkevich 📅 Thursday, November 6 🕗 9am CT 👉 https://t.co/DmWKDSmQDE
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Fantastic review! Everything you ever wanted to know about PART.
Primary age-related tauopathy #neuropath
https://t.co/TYa9UhT00j
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Agreed! Can’t count how many times I have seen alternative diagnoses first suggested by MRI findings or even refinement of “Parkinson’s” diagnosis, such as an atypical syndrome or even rarer things like PLA2G6 mutation. While volumetric tools often lag behind relative to
Should every person with suspected Parkinson’s get an MRI? For decades, neurologists have relied on history and examination as the gold standard for diagnosing Parkinson’s disease. Routine MRI scans have not been recommended for people with a classic presentation. However, more
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18F-FDG PET in detection of primary age-related tauopathy (PART) – Is there a role? Insights from an imaging-pathology correlation study https://t.co/KwybJSTp8z
alz-journals.onlinelibrary.wiley.com
INTRODUCTION Primary age-related tauopathy (PART) is defined by neurofibrillary tangles (NFTs) with absent-minimal amyloid beta (Aβ) plaques. Currently, definitive diagnosis of PART occurs with...
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Last day of #AAIC25! Even though I couldn’t be there in person anymore, I was able to see @NeuroNiels shine on stage, as presenter and first-time session moderator. Very proud! 🤩
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Very interesting work! 🤩
Ever wondered how small vessel disease is related with AD-proteinopathies in the medial temporal lobe? 🍤🧠 🔗 https://t.co/LND53ECdjK In our new work we show: ✅CAA severity is linked to Aβ-plaques and tau ❌Arteriolosclerosis is not, but is associated with ePVS burden
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Very happy to be in #Toronto for #AAIC25! Great kick-off with the #AIC preconference, @EmmaCoomans presenting the year-in-review. Also, come visit my poster AIC-310 with lots of MRI-pathology studies!
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🚨 Another new manuscript from the team! On an imaging marker for LATE-NC as co-pathology in neurodegeneration.
Using post-mortem in situ MRI, Wesseling et al. show that brain donors with LATE-NC have lower amygdalar and hippocampal volumes than non-LATE-NC donors, even when correcting for regional phosphorylated tau, amyloid-b, and a-syn. https://t.co/z7zmVvvarl
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🚨 New manuscript from the team! Cross-disease assessment of volume change and pathological accumulation in hippocampal subfields. First-first by @maud_bouwvrouw! 🥳 https://t.co/uG9yYLpT55
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🚨 New manuscript from the team! @NeuroNiels’ first first-author paper, a wonderful collaboration with Qynapse! https://t.co/w4q1CYkdBQ
pubmed.ncbi.nlm.nih.gov
For both clinical phenotypes, cortical volume is affected by Aβ and neuro-axonal damage, but in opposing directions. Differences in volume-pathology relationships between clinical phenotypes are...
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So excited and honored to be invited to present the opening plenary at #AIC2025 this year in Toronto! 🧠 🙏 I would be very grateful if you could help me gather the most inspiring papers (including your own!) of the past year by completing this survey:
🚨Calling all neuroimagers! Help @EmmaCoomans shape the opening plenary at #AIC2025 (Toronto, July 26th) "Accomplishments of the Past Year" and share the most impactful neuroimaging research from the past year via this brief survey (~5min) by May 30th. https://t.co/5KpVMpzC7a
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Always my favourite post at the beginning of the year: Registration for our course “Biomarkers for neurodegenerative diseases” is now open! This year’s edition takes place at @UCLIoN in central London on May 12-16. https://t.co/ix28Tw1VHQ
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We live in a state of perpetual dissociation from the almost unbearable wonder of being alive. But if we fell asleep each night remembering “the singularity we once were” and awoke each morning with the bright awareness that every atom in our bodies can be traced to one of the
themarginalian.org
We live in a state of perpetual dissociation from the almost unbearable wonder of being alive. Wonder is always an edge state, its edge so sharp it threatens to rupture the mundane and sever us fro…
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Come join the international Lewy body dementia conference in Amsterdam! 29-31 January 2025. #ILBDC2025
https://t.co/caRxZetZzu
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First first-author manuscript of PhD student submitted in early October, got desk- rejected after the journal was unable to find reviewers (20+ invitations sent out). Not the most motivational way to start you academic career! #butPIstillproud
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Today was an interesting day at the Dutch Dementia Researchers Conference (#DDRC). Well organized and nice variety of topics! #OneInFive
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Highly recommend to join this session 🤩
📢 Announcing the @ISTAART @AtypicalPIA journal club for 2024! 🧠 We will feature a study led by @NehaASingh4, presented by @NeuroNiels and additionally discussed by @IamColinGroot. 📆 When: Nov 07, 10:30 AM CT 🔗 Register here: https://t.co/8xYDLe14ts
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Wonderful work, also in line with some of our findings on SV2A and synaptophysin in #Lewy body disorders -
pubmed.ncbi.nlm.nih.gov
Regional differences in synaptic degeneration may underlie differences in clinical presentation and neuropathological disease progression in Parkinson's Disease (PD) and Dementia with Lewy bodies...
SV2A PET tracers may help detecting synaptic loss in vivo, but a map of SV2A in human brain tissue is missing. We mapped SV2A & synaptophysin in #alzheimer & others to enhance interpretation of PET studies. https://t.co/fhuA3ctebV
@UCSFmac @GrinbergLab @HAIconference @ISTAART
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Researchers at our department presented the Open Science guidebook for Neuroscience - perfect timing during #OpenAccessWeek! 🥳
Full house at our OS group's workshop day, which starts with a big celebration of their almost finished Open Science Guidebook for Neuroscience 🥳🔓
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Very happy to see this work on AD clinical variants published! 🤩
🚨‼️ Distinct anatomical distribution of neuroinflammation in a small cohort of AD clinical variants (Typical, behavioral/dysexecutive, and PCA). Read the full story👉🏻 https://t.co/JK1sSd7iuD
@JeroenHoozemans @HolstegeHenne @NeuroLaura @DrNeuroChic @NBB_BrainBank
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