INEM NECKER
@NeckerInem
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INEM is a biomedical research center in molecular medicine with focus on immunology, cell biology, metabolism, microbiology, and hematology.
Paris, France
Joined October 2019
And that’s a wrap! 🎉 The INEM 10-YR Anniversary Symposium was filled with inspiring talks, dynamic Flash Talks by young researchers, and engaging discussions. Thank you to everyone who joined us to celebrate science and collaboration! #INEM10YEARS #INEM2024
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[PUBLICATION] The @MEMBRAMICS_lab shows how Influenza A virus rewires ER lipid metabolism to promote viral ribonucleoproteins egress. 🦠. 📖 Carla Alemany @JulianeDaGraca sharing the first authorship 👏🏼. w/ @institutpasteur & IPNP.@PLOSBiology
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[PUBLICATION] NEW in @CellReports .@JulianeDaGraca et al. show that ER-endosome contacts act as hubs for phagophore formation during starvation. 📖 @MEMBRAMICS_lab
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👏🏼 Proud to see @JulianeDaGraca, former PhD student at INEM, honored with the 2025 Beth Levine Thesis Prize for her outstanding work on autophagy, supervised by Etienne Morel @MEMBRAMICS_lab.
🎉 Congratulations to @JulianeDaGraca, recipient of the 2025 Beth Levine #ThesisPrize! Her outstanding research @MEMBRAMICS_lab on the role of ER/Endosome contact sites in the regulation of #autophagy captures the award's spirit of excellence and innovation. 👏
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RT @CFATG: 🎉 Congratulations to @JulianeDaGraca, recipient of the 2025 Beth Levine #ThesisPrize! Her outstanding research @MEMBRAMICS_lab o….
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#France2030 | Félicitations à Guillaume Canaud @CanaudLab, lauréat d’une Chaire d’excellence en Biologie/Santé pour son projet sur les malformations vasculaires liées à KRAS. 🎯Objectif : développer des thérapies ciblées pour une médecine ultra personnalisée. 👏🏼.
📢#France2030 15 nouveaux chercheurs et chercheuses d'exception récompensés pour les « Chaires d’excellence en Biologie / Santé » !🧑🔬.Ce dispositif vise à renforcer l’attractivité de la recherche biomédicale française🧪🇫🇷🥼.Pour découvrir les lauréats👉
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[CAREER] A 3-year PhD position is open in Paris to explore how air pollution contributes to CKD. The project combines experimental and environmental science and is hosted by INEM & LISA. 📨 Apply by Sept 1. 🟢 Start Nov–Dec 2025.
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🚨 We're hiring! INEM is recruiting a Group Leader in #Immunology. Join a vibrant biomedical research institute with strong clinical & academic links. 🗓 Apply by Sept 20, 2025. 🔗 More info:
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[PUBLICATION] New study with the Bharat lab @CellBiol_MRCLMB reveals the structure of the Neisseria meningitidis filamentous phage MDAΦ. Cryo-EM/ET show how phage bundling supports biofilm formation & pathogenesis. @MathieuCoureuil @PNASNews.
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[PUBLICATION] PIK3CA mutations in Schwann cells trigger neuropathy by disrupting nearby healthy tissues. This non-cell autonomous effect shifts local metabolism toward aerobic glycolysis. Early alpelisib treatment is key | @PNASNews .🔗@CanaudLab
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@ScienceMagazine @pontoglio_marco @FabiolaTerzi @IsnardPierre1 @Nico_BioloGeek @CanaudLab @turinsky47926 @NKuperwasser @MRabant @SfrNecker The study highlights how YAP hyperactivation in podocytes reprograms cell fate and triggers PEC proliferation, revealing CTGF and HB-EGF as key mediators, and therapeutic targets, in crescentic glomerulonephritis.
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[PUBLICATION] Podocyte-specific YAP activation drives crescentic glomerulonephritis via cross-talk with parietal epithelial cells. 🌙.A study from the Terzi & Pontoglio labs now out in Science Translational Medicine @ScienceMagazine.
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🗓️ Join us on July 4, for a #seminar with David Sabatini, group leader at @IOCBPrague. Dr. Sabatini will explore nutrient sensing by the mTOR pathway. Don’t miss it! @MarioPende
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[PUBLICATION] mTORC1 governs multiciliated cell differentiation by favoring progression through a cell cycle variant without DNA replication and by acting on cytolinker proteins for centriole disjunction. 📖Read more: @MarioPende
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[PUBLICATION] First report of successful pregnancies after treatment with alpelisib for PIK3CA-related overgrowth spectrum. ➡️Fertility preserved.➡️No embryotoxicity.➡️Disease remained responsive after treatment pause. 📖Details here:
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🗓️ Join us on June 20, for a #seminar with Jean-Emmanuel Sarry @jeansarry, team leader at @crctoncopole. Dr. Sarry will explore Mitohormesis and metabolic adaptations in response to therapeutic stress in acute myeloid leukemia. Don’t miss it!
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🚨 We're hiring at INEM!. The Immunity in Health and Disease team, led by @FillatreauSimon, is recruiting:. 🔬 Assistant Engineer.🧑💼 Horizon Europe Project Manager (ARTiDe project). More info & how to apply: . 🔗 🔗 @Inserm.
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🗓️ Join us on June 13, for a #seminar with Han Li, Principal Investigator and leader of the cellular plasticity in age-related pathologies group at Institut Pasteur. Prof. Li will explore senescence induced-cellular plasticity in health & disease. Don’t miss it! @MarioPende
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🗓️ Join us on Friday, June 6, for a #seminar with Elvira Mass, Head of the Department of Developmental Biology of the Immune System at @LIMES_Bonn. Prof. Mass will explore the developmental programming of tissue-resident macrophages. Don’t miss it!.@VenteclefNicol1 @ImmediabL
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🚨 We're hiring! The @ImmediabL team is looking for:.🧪 1 Postdoc.🧬 1 Research Assistant / Bioinfo/ Tech.📍 Paris | Start Sept 2025.📄 Full details + apply: @DrFAlzaid
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[PUBLICATION] Treating patients with somatic PIK3R1 mutations using alpelisib leads to clinical and radiological improvement. A promising step toward targeted therapy in PIK3R1-related disorders. 📄Read more: @CanaudLab @morin_gbrl @EmboMolMed
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