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Roman-Ulrich Müller Profile
Roman-Ulrich Müller

@MuellerRom

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scientist and MD, aiming to bring novel strategies to fight kidney disease from basic research to the clinic with a focus on dietary and metabolic interventions

Joined April 2021
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@MuellerRom
Roman-Ulrich Müller
27 days
1/.🚨 Big news from our Genes&Kidney Working Group at the @ERAkidney .We just released a consensus statement in Nephrology Dialysis Transplantation aiming to bring us closer to precision medicine in CKD. 🧬🩺.🧵 THREAD 👇.
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@MuellerRom
Roman-Ulrich Müller
9 days
@PKD_Int
PKD International
9 days
🎥🧪 SGLT2 Inhibitors: Should They Be Used in ADPKD?. In this new video, Prof. @MuellerRom — medical doctor and researcher at the University of Cologne — explores one of the most debated questions in the field of kidney disease today 👇. #PolycysticKidneyDisease
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@MuellerRom
Roman-Ulrich Müller
11 days
RT @ERAkidney: 💥 Don't miss the last WG publication by G&K - Genes & Kidney.📌Chronic Kidney Disease of unexplained cause (CKDx): a consensu….
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@MuellerRom
Roman-Ulrich Müller
12 days
Cases in which a diagnosis underlying Chronic kidney disease has not been established need a clear name: CKDx.
@torra_roser
Roser Torra
13 days
It is a must! Do not miss it!!. We all should adopt the nomenclature for CKDx with/without 🔬histology and or 🧬genetic testing.
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@MuellerRom
Roman-Ulrich Müller
23 days
RT @schumacherbj: Enabling healthy ageing: @Leopoldina discussion paper recommends shift in focus in research and medicine. We are proposin….
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@MuellerRom
Roman-Ulrich Müller
23 days
RT @PKD_Int: #PKDKnowledge — A Shared Vision of Open Science. “Why is open science important for polycystic kidney disease?”.It’s a vital q….
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@MuellerRom
Roman-Ulrich Müller
25 days
RT @gunnar_heine: Hello CKDx !.Dr. Halbritter @MuellerRom @LucileFigueres @ecorneclegall and others introduce."Chronic Kidney Disease of un….
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@MuellerRom
Roman-Ulrich Müller
27 days
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@MuellerRom
Roman-Ulrich Müller
27 days
9/.Shoutout to the co-authors:.@ecorneclegall Jan Halbritter @LucileFigueres Albertien van Eerde John Sayer Tom Nijenhuis Maria Vanessa Perez Gomez Matias Simons Nikola Zagorec Giovambattista Capasso Ewout Hoorn.
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@MuellerRom
Roman-Ulrich Müller
27 days
8/.📝 Read the full consensus statement:.🔗 Let’s #OwnTheUncertainty together and drive CKD care toward a cause-directed, precision future. 🌍🧬.
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@MuellerRom
Roman-Ulrich Müller
27 days
7/.📣 To the #nephrology community:.We invite all clinicians, geneticists, pathologists & data scientists to:.✅ Use CKDx in your practice & research.✅ Share cases where h/g flags made a difference.✅ Tell us what metadata would help refine diagnostics further.
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@MuellerRom
Roman-Ulrich Müller
27 days
6/.💡 Key takeaways:.1️⃣ CKDx ≠ diagnostic dead-end.It’s a launch pad to keep digging for the cause. 2️⃣ The h/g flags, lab & imaging checklists allow standardized data collection across centers. 3️⃣ The model aligns with KDIGO 2024’s cause-first approach (CGA classification).
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@MuellerRom
Roman-Ulrich Müller
27 days
5/.This footprint gives a snapshot of diagnostic progress:.🔍 How far along the journey are we?.➡️ What’s the next step?.It’s a simple, shared language for clinicians, pathologists, and researchers alike.
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@MuellerRom
Roman-Ulrich Müller
27 days
4/.But CKDx isn’t just a label — it’s a call to action. We’ve added a “diagnostic footprint” to make it actionable:. CKDx h+/- g+/-. Where:.• h+ = biopsy done.• g+ = genetic testing done.• h- / g- = not done.
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@MuellerRom
Roman-Ulrich Müller
27 days
3/.🔹 Our solution: introduce CKDx.➡️ Chronic Kidney Disease of unexplained cause.A unified term to replace the confusing patchwork of current "catch-all" diagnoses.
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@MuellerRom
Roman-Ulrich Müller
27 days
2/.❓Why this matters:.Up to 25% of CKD cases lack a clear cause. We're often stuck with vague labels like "hypertensive nephropathy" or "FSGS"—diagnoses of convenience that hinder:.– Prognosis.– Trial inclusion.– Targeted therapies.
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@MuellerRom
Roman-Ulrich Müller
28 days
RT @ERAkidney: 📢 Join us at the ERA Journal Club e-seminar!⁣.*SGLT2 inhibition for patients with #ADPKD – closing the evidence *⁣.📅 June 19….
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@MuellerRom
Roman-Ulrich Müller
30 days
RT @Nefrontera: Great article about Chronic Kidney Disease of unexplained cause by the Genes and Kidney @ERAkidney group!. ✅ CKDx assessmen….
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@MuellerRom
Roman-Ulrich Müller
1 month
RT @LucileFigueres: Proud to have contributed to our @ERAkidney WG Genes&Kidney consensus statement on CKDx (X for unexplained cause) publi….
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@MuellerRom
Roman-Ulrich Müller
1 month
RT @gunnar_heine: @torra_roser @ERAkidney @NDTsocial @hjanders_hans @KateStevens @MarkusAtHome Not so bad, since - as a unique compensation….
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