Molecular Metabolism
@MolMetab
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Molecular Metabolism is an open access journal reporting breakthroughs with the potential for transformative impact on today's metabolism research.
Joined October 2014
πΎππππ π€πͺπ© π€πͺπ§ πππ©π€πππ§ ππ¨π¨πͺπ! π§¬Cover Story: MGP deletion in adipose progenitors promotes #fibrosis and impairs #adipogenesis via PDGFRΞ±βΊ;DPP4βΊ cells (@dgsomucla) β‘οΈ https://t.co/zyEcAiP7B1 π§¬Browse the full edition: https://t.co/4J7JBea4KZ
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#Insulin acts on NTS #astrocytes to lower hepatic #glucose output. It triggers #endozepine (DBI/ODN) release, modulating GABAA signaling and reducing #liver glucose production, even in HFD-induced #insulinresistance. ποΈ@UniversityLeeds @LUUFoBSoc π https://t.co/b0z3MdTnBn
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GraniteShares announced distribution rates for the YieldBOOSTβ’ HOOD ETF (HOYY) as of October 30, 2025 $HOYY HOYY: Standardized performance: Since Inception (9/30/2025): +1.08%
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Happy to share that another part of my thesis work studying circadian gene Per1 in liver metabolism is online in @MolMetab today! In this work, we characterized how Per1 mediates time-restricted feeding effects in different sexes. https://t.co/LlfmfYUn2y
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Deleting both hepatic ACC1/2 reverses #fattyliver & #fibrosis but disrupts #metabolism. Selective ACC2 inhibition with partial ACC1 suppression could restore #liverhealth. ποΈ@UNSWBABS π https://t.co/YHuoNfubiE
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Loss of Dax1 in AgRP neurons increases energy use & BAT #thermogenesis, protecting females from diet-induced #obesity - via GR-HDAC3-mediated Crfr1 repression. ποΈ@SeoulNatlUni π https://t.co/xy9GsnBpoa
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Is @OpenAI's browser a real threat to @GoogleChrome? π€― On this week's "The Flip," @PatrickMoorhead and @DanielNewmanUV face off in a classic battle of established power vs. disruptive force. Daniel argues that OpenAI's Atlas browser will win the younger generation and find the
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The diet-derived gut microbial metabolite 3-phenylpropionic acid reverses insulin resistance and obesity-associated metabolic dysfunction #obesity #MASLD @MolMetab
https://t.co/8ssNVFq50V
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Check out the latest paper from the MacDougald Lab in @UMPhysiology published in @MolMetab showing how adipocyte Wnt signaling regulates lipid and mitochondrial metabolic processes in stromal-vascular cells and adipocytes in fat tissues. https://t.co/DLiB7RxdBn
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Conditional TERT expression reduces #insulinresistance & #glucoseintolerance in #obese mice by limiting adipose stem cell senescence & oxidative stress, promoting ASPC expansion, differentiation & #adiposetissue plasticity. π¦@crcm_marseille π https://t.co/ymT6KBkR78
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An update on beta cell GABA biology using mouse genetics to inactivate GAD65 and GAD67. GABA is dispensable for beta cell mass, but essential for dynamic function #islets @MolMetab
https://t.co/6mMXoDkJvQ
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VMH neurons contribute not only to emergency glucose mobilization, but also to day-to-day #glucose #homeostasis. This study shows that VMH^Cckbr neurons promote Ξ²3-adrenergic #lipolysis and substrate availability during short fasts. π¦@UMich π https://t.co/CnyZd2gPh8
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β° Circadian clocks in #leptin-sensitive neurons control when we crave tasty food. Breaking these clocks disrupts daily eating rhythms, alters #metabolism, and promotes diet-induced #obesity. ποΈ@UniLuebeck π https://t.co/TDORAI758l
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π€ Flash Talk Awards 2025 π€ Congratulations to this yearβs winners for their excellent short presentations at the 12th Helmholtz Diabetes Conference! π₯³ π Isabel Reinisch (@ETH_en) π Valentina Dorta (@cimususc) #HelmholtzDiabetes2025
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π The Helmholtz Diabetes Lecture Award goes to π£π΅πΆπΉπΆπ½π½ π¦π°π΅π²πΏπ²πΏ (@UTSWMedCenter), sponsored by the DZD (@DiabResearch)! His lecture on βHormonal harmoniesβ is a true highlight and a perfect conclusion to the conference. Congratulations! π #HelmholtzDiabetes2025
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Performance Matters. Precision Matters. Predictability Matters. Introducing OptiBLOCK mini
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A big THANK YOU goes to all our #sponsors of the 12th Helmholtz Diabetes Conference! Your support makes this international meeting possible. π #HelmholtzDiabetes2025 #Diabetes #Liver
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Research from postdoc Romina Uranga (now at @NewCollegeofFL) and the MacDougald lab in @UMPhysiology published in @MolMetab explores the cell specific effects and cross talk of different cell types resulting from Ξ²-catenin deficiency in adipose tissue https://t.co/sXKYWcxiPC
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Worth a read for context on the "lean mass muscle loss" #obesity GLP-1 medicine debate. Keep an eye on muscle function and health, diet quality and resistance #exercise and not just the DXA scan @SA_Diabetes @MolMetab #weightloss
https://t.co/W4fx6PqplL
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Yesterday we kicked off the 12th Helmholtz Diabetes Conference in Munich! Stephan Herzig opened the meeting, highlighting the importance of international exchange and collaboration in #diabetes research. Three days full exciting science! π #HelmholtzDiabetes2025
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Based on studies in mice the authors propose the core clock system as a potential therapeutic target to improve cardiometabolic health. https://t.co/FH2wQ9VCir
@MolMetab
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The liver clock modulates circadian rhythms in white adipose tissue #adipogenesis #lipidmetabolism @MolMetab
https://t.co/o4yct2rl61
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