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Miruna Popescu, MD

@MirunaPopescu13

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PGY-5 pathology trainee | Former IVS @UABPathology | #PathTweetAward 🥇 23 | #GUPath #GynPath #BSTPath | YT @MirunaPopescuMD | Creator of #PRLUSS | Views my own

Stuttgart, Germany
Joined February 2022
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@MirunaPopescu13
Miruna Popescu, MD
1 year
I'm starting a YouTube playlist of short, high-yield videos for the AP boards (5 minutes or less). It's still small at this point, but it's going to get bigger 💪🏽 If you're interested, check it out: #PathTwitter #pathboards #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
1 year
@GeronimoJrLapac Let's add this one to this meme 👇🏻
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@MirunaPopescu13
Miruna Popescu, MD
2 years
🎉It's finally here: an organized list of all of my educational pathology content 👇🏽 Here you'll find pics, digital slides, short reviews, videos & more covering almost all subspecialties! Many thanks to @JMGardnerMD for being such an inspiration! Enjoy!
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Maybe you don't know this yet, PGY1 path residents, but for whatever reason, no matter if you love or hate #dermpath (although, let's be honest, what's to hate about it?), this 👇🏽 will soon become one of your favorite spot diagnoses. So, what is it? #PathTwitter #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Friday grossing 📸 Organ? Diagnosis? #PathTwitter #Grossognosis #GIPath
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Pop quiz - Endometrial tumor ♀️🔬 1. What's your (differential) diagnosis? 2. What is one IHC marker you would order to confirm the diagnosis? 3. One frequent molecular alteration? Have a great weekend! 😊 #PathTwitter #GynPath
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@MirunaPopescu13
Miruna Popescu, MD
4 months
During my time at @UABPathology I got the chance to engage more with adrenal gland neoplasia, so today I'm sharing with you my wall-hanger 🔬 on adult adrenocortical carcinoma (ACC). I hope it will prove useful for your practice 😊 #PathTwitter #Endopath #GUPath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Hysterectomy specimen showing a rare #GynPath entity! 🔬 Known HPV+ status. Can you guess what it is ❓ Answers later in the 🧵👇🏽 #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
1 year
First video of my Genitourinary Pathology Series is up on #YouTube and available here: In it, I discuss an algorithmic approach to a common pitfall in the evaluation of TURBT specimens. Enjoy! 😊 #PathTwitter #GUPath #Bladdercancer
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Lesion from the fingernail bed. What's your diagnosis? 🔍🔬 #PathTwitter #BSTpath #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 years
🔬 Found in an inguinal lymph node of a middle-aged man. What do you think this could be ❓ Answer down below in the 🧵👇🏽 #PathTwitter #LymphNodePath
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@MirunaPopescu13
Miruna Popescu, MD
1 year
1. Adult, breast core needle biopsy. Poll & short discussion below 👇🏽 #PathTwitter #Breastpath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
(1/10) 15 y/o M -> Rx: well-circumscribed lytic expansile mass, metaphysis of distal femur 🦴 MRI: fluid-fluid levels. Your diagnosis on these 2 high power images? Follow the 🧵👇🏽 for a poll & a short tweetorial. #BSTPath #PathTwitter #bstpathpodcast #pathresidents #pathfellows
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Middle-aged female with a mass in the ... One image, one organ, one diagnosis. Can you get it right? 😉 Hint: of all tumors arising in this organ, this is a rare one (<1%) Answer & a short review: #PathTwitter #pathresidents #ENTPath
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Chronic endometritis = plasma cells + significant stromal & glandular metaplastic changes ❗️ 1-2 plasma cells in an otherwise N endometrium ≠ chronic endometritis Occasional plasma cells in other conditions ❗️ (last pic) Dr. Parra-Herran, @pathologyCast YouTube video #gynpath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
For all #breastpath enthusiasts, a case of a rare entity. 60 y/o F of Asian descent presents with a 3 cm breast mass. What's your diagnosis? 🔬 Any differentials you would consider? More images here: Answer & short review later on KiKo, link👇🏽 #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Here's another exceptionally rare one for the annals of #PathTwitter . Presenting as a colonic polyp endoscopically, histology revealed the following lesion 👇🏼 What's your diagnosis? 🔬🔍 Would you order any additional stains? #GIpath
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Testis - #GUPath classic 🔬 Short 🧩 with 3 ❓ 1. Diagnosis? 2. Can you name two common differentials? 3. What IHC stains would you use for confirmation? Bonus question: what is one commonly associated finding in the adjacent testicular parenchyma? #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
5 months
We are in the ovary. One high power image provided. Can you get the diagnosis right or is it #TooCloseToDiagnose ? #PathTwitter #GynPath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Abnormal uterine bleeding - stromal breakdown ✅ Stromal crumbling & condensation -> "blue balls" ✅ Dilated stromal vessels w/ fibrin thrombi (sign of pathological process) ✅ Reactive epithelial changes - papillary/eosinophilic syncytial "metaplasia" #pathoutpic #GynPath
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Perimenopausal F. D&C, cervix. What's your opinion? #GynPath #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Most dramatic example of atypical mycobacteriosis I've seen in an immunocompromised patient. That ZN stain is practically screaming at you! #GIPath #PathTwitter #PathX #microbiology
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@MirunaPopescu13
Miruna Popescu, MD
2 years
14 y/o male w/ a later neck mass. What's your diagnosis? Hint: this one is a name-alike but not a look-alike of another lesion. Would you order any IHC to confirm? #PathTwitter #BSTPath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Last quiz of 2022! This one's juicy. Middle-aged F, tumor nodule in the oral mucosa. Can you guess what it is? Differentials? IHC & Answer will be posted on #KiKo next year😄😉 Have a great new year, #PathTwitterFamily ! 🍾🥂 May 2023 bring even more learning opportunities! Cheers
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@MirunaPopescu13
Miruna Popescu, MD
2 years
One image, two questions. Organ? Diagnosis? #PathTwitter #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Aneurysmal bone cyst (ABC) ➡️multiloculated blood filled cyst ➡️septa composed of a proliferation of bland fibroblasts ➡️osteoclast-like giant cells ➡️hemorrhage - fresh and old (hemosiderin-laden Mf) ➡️new bone formation (osteoid-like material, woven bone) #PathTwitter #BSTPath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Hot off the microscope stage #BSTPath case. Middle-aged M w/ a subpleural lung mass. Which 2 IHC stains you would definitely want to 👀🤔? What's the most common 🧬fusion seen in these tumors? Answer later on KiKo, link will be posted in the 🧵👇🏽 #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
5 months
#GUPath enthusiasts, you are going to ❤️ this one. One high-power 📸 of a 🔪predominantly cystic renal mass. What is your first diagnostic impression? #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
5 months
Can you make the diagnosis from one high-power image or is it #TooCloseToDiagnose ? Which IHC would you do to support the dx? #PathTwitter #BSTPath #Hemepath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Adult-type granulosa cell tumor of the ovary (SCST) ▶️Diffuse growth of uniform cells w/ angulated nuclei ▶️Reticulin stain shows fiber staining around groups of cells rather than around individual cells - DDx. Fibrothecomas ▶️Calret, Inhibin A, FOXL2 +, EMA- #pathology #GynPath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
A cute #dermpath twofer to brighten your Saturday! Can you guess what it is? #PathTwitter #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
11 months
The eternal love of every pathology resident, grossing (mhm 😅) 🔪📸 What's the organ? What's the procedure? H&E pics to come 👇🏽🧵 #PathTwitter #Grossognosis #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Synovial sarcoma refresher 📖 mono- (most) or biphasic (=spindle+epithelial) 🔬 spindle cells, but nuclei rather ovoid, high N:C ratio, densely packed in sheets; epithelial comp may form glands 🔬EMA+, CD34- Unique 🧬 t(X;18)(p11;q11), mostly SS18:SSX1 => no pleomorphism #BSTPath
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@MirunaPopescu13
Miruna Popescu, MD
1 year
PGY1 path residents, remember this one 👇🏽 Esophagus, biopsy. Classic viral cytopathic effect! The three Ms of HSV: ✅ Multinucleation ✅ Molding ✅ Margination (of chromatin) Dx. HSV esophagitis Remember to order IHC if in doubt. #PathTwitter #GIPath #HSV
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@MirunaPopescu13
Miruna Popescu, MD
5 months
Did you know❓ Multinucleated tumor giant cells are actually a common feature of alveolar rhabdomyosarcoma (ARMS). #BSTPath #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Nephrogenic adenoma, misnomer! ✅metaplastic reactive change ✅tubulocystic, papillary, polypoid ✅cuboidal/hobnailed cells w/ eosinophilic cytoplasm & smudged nc, no prom. nucleoli ✅thickened hyalinized BM around tubules ✅limited to LP, no stromal reaction #GUpath #pathoutpic
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@MirunaPopescu13
Miruna Popescu, MD
2 years
❓ Let’s do a quick #BSTPath quiz ❓ 60 y/o F with a retroperitoneal mass 🔪 Follow the 🧵 👇🏽 for the answers & for a short tweetorial (1/11) #PathTwitter #pathoutpic #pathtweetorial
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Mega Case Indexes are an invaluable virtual learning resource, freely available @ ! What's in my Mega Index? 📸Lots of photomicrographs 🔬WSI digital slides 📚Short reviews of the illustrated entities 📘Cases covering ~all subspecialties. Check it out!👇🏽
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Carcinosarcoma (formerly MMMT) of the uterus ➡️biphasic T w/ high-grade carcinomatous & sarcomatous components ➡️+/- heterologous diff. (e.g. rhabdomyosarcoma, as shown) ➡️usually p53 mutant & p16 block positivity in both comp. ➡️DDx: dediff. endometrial Ca #Pathoutpic #Gynpath
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@MirunaPopescu13
Miruna Popescu, MD
1 year
One photo to illustrate a benign entity #beautyintheb9 Two questions to stimulate the mind. 1. What's the organ? 2. What's the diagnosis? Check link for answer & short description 👇🏽 #GUPath #Endopath
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@MirunaPopescu13
Miruna Popescu, MD
8 months
How sneakier can it get?😲 Invasive lobular carcinoma masquerading as lymphocytic infiltration in a reexcision for positive margin 🔬Always watch out for what seem to be lymphocytes around ducts👉🏽periductal targetoid growth of ILC cells 🎨PCK lights up like 🎄 #Breastpath
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@MirunaPopescu13
Miruna Popescu, MD
1 year
This is one of those #pulmpath cases where you have to take a step back & call your clinician. A lesson in not rushing to conclusions. Middle-aged F with a lung mass. Bx was performed 👇🏽 More images in the comments. A poll, IHC & answer down in the 🧵 #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Continuing the series of #SalivaryGlandTumors here's another common entity. Frequently seen in middle aged adults (♀️>♂️). What's your diagnosis? 🔍 What IHC would you order? 🔬 Diagnostic hint: PNI is a hallmark of this T. 🗨️Further info later in the 🧵 #PathTwitter #entpath
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@MirunaPopescu13
Miruna Popescu, MD
5 months
Traditional serrated adenoma Serrated colon polyp, precursor of BRAF-mut MSI CRC ➡️Typically (tubulo)villous ➡️Slit-like serrations ➡️Abundant ectopic crypts ➡️Pencillate dysplastic(-appearing) nuclei like in a typical TA, but☝🏻 with eosinophilic cytoplasm #GIPath #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
11 months
Hello #PathTwitter friends. A quiz for a Thursday evening. Thyroid. What do you think are these interfollicular cell nests ❓ ✅Answer tomorrow in the 🧵 #EndocrinePath #ThyroidPath #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 years
A classic #BSTPath case! 38 y/o M w/ a deep thigh mass. These tumors tend to metastasize to all sorts of weird locations. What is your diagnosis? 🔬🤔 What is the characteristic 🧬fusion? Is the area in the 3rd image concerning? Answers & review later on KiKo, link in the 🧵👇🏽
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Here's a classic! Myrmecia wart - marked acanthosis and beautiful eosinophilic intracytoplasmic inclusion bodies, just like in the textbooks 📖🔬 #PathTwitter #dermpath #pathoutpic
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Pulmonary corpora amylacea 🫁 - relatively common in the elderly (thank you, Dr. Butt, for pointing this out!). #pulmpath #lungpath #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Just some Giardia lamblia trophozoites hanging around at the surface of the duodenal mucosa.🦠 As my parasitology professor from university used to say when referring to these little protozoans: look at those fine ladies!💃
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Middle-aged F, tumor involving axial skeleton (C7)🦴 What's your diagnosis?🤔 What is the characteristic IHC profile of this entity?🔬 Any underlying molecular abnormality?🧬 Could you name two DDx?🗨️ Answers & more pics: #PathTwitter #BSTPath
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@MirunaPopescu13
Miruna Popescu, MD
7 months
Happy to share that I'll be (now officially) attending the USCAP meeting in Baltimore this year 🎉 It'll be my first 😎 Looking forward to meet many #PathTwitter folks! See you in Baltimore 👀
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@MirunaPopescu13
Miruna Popescu, MD
5 months
Fat-poor pleomorphic lipoma. ➡️ Notice floret-like multinucleated giant cells 🌸 Next to wiry collagen bundles & bland spindle cells in a "school of 🐟" growth pattern. Oh, the oximorons of pathology. #BSTPath #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
1 year
#GUPath quiz 🧩 Undescended #testis . Last stain is PAS. What's your diagnosis? 🧐 Answer & a short description: #Beautyintheb9
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto) ➡️ irregularly shaped pale areas w/ mononc. cells, necrotic material & lots of karyorrhectic debris (nuclear dust), latter may extend beyond node capsule. ➡️ CD68 highlights histiocytes around necrotic areas. #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Curettage, uterine corpus. Low-grade (FIGO G2) endometrioid carcinoma. Then this area 👀 (last 2 images). Any idea what this could represent? Some mitoses present on H&E 🔬 CK - ; E-Cadherin - ; Desmin - ; PAX8 - ; p53 - #PathTwitter #gynpath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
➡️Mature adipocytes +/- fibrous septa & lobular arrangement ➡️Clusters of branching capillary-sized vessels (frequently peripheral) ➡️Fibrin thrombi in vessels ➡️No atypia in either adipose or vascular component = Angiolipoma #PathTwitter #BSTPath #pathology #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 months
Kidney mass, CNB. DDx? #IHCPath work-up? #PathTwitter #GUPath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Skin nodule. Typical microscopic appearance. Your diagnosis? 🔍 #PathTwitter #dermpath #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Wrapping up 2022 with a last quiz & tweetorial, this time on #Breastpath ! 70 y/o F with a breast mass (BI-RADS 5). Core needle biopsy shown. (1/8) Follow the 🧵👇🏽 for some MCQs. A short review of this entity & more pics on KiKo, link in the last post. #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Uterus tumor extending into parametrial soft tissue and showing characteristic placental-like gross features. What's your diagnosis on #extremelylowpower ? H&E photos after the weekend! 😎🍹 #PathTwitter #GynPath
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@MirunaPopescu13
Miruna Popescu, MD
2 months
It's a fuzzy situation 🦠 in this colon biopsy. What could it be? 🧐 #GIPath #crittersontwitter #PathTwitter #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
1 year
There's no better place to read #GUpath from one of my favorite #pathology book series than at the Greek seaside. Sorry to miss y'all in Dublin. This September it's all about swimming & renal cancers. Have a great Sunday evening everyone!
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Renal mass. All three areas found in the same tumor. What is your diagnosis? 🔬 #PathTwitter #GUPath #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Postmenopausal ♀️ with a uterine mass, curettage specimen. What is your diagnosis? 🤔 Any IHC you would order? 🔬 #PathTwitter #Gynpath #pathoutpic
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@MirunaPopescu13
Miruna Popescu, MD
2 years
♂️ 28 y/o. Testicular mass. What's your diagnosis🔍? What immunostains would you order? 🗨️Further discussions & info later in the chat. #PathTwitter #GUPath
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@MirunaPopescu13
Miruna Popescu, MD
3 months
#Cytopath #Pulmpath BAL fluid. Can you name this beauty I found 🏋️? #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
3 months
1/ Fifth #PathTweetorial of 2024 focusing on a particular phenomenon seen in some #gynpath ovarian tumors Kickstarting w/ a ❓ As usual, bonus YT📹 at the end Also 🚨wallhangers throughout 🔬Image credits go to dear friend @Gagandeepk5MD #PathTwitter #PRLUSS #pathoutpic
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Hello #PathTwitter , I come bearing gifts. An ugly, aggressive, and rare #GynPath tumor to please the 👀. 80-something F, endometrial curettage. What are your thoughts? The IHC might surprise you. 2nd set of H&E images 👇🏼
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@MirunaPopescu13
Miruna Popescu, MD
2 years
No history this time. Just two images. What's the organ? What would be on your differential? Any IHC? Answer, IHC + more pictures here: An organized list of all my educational pathology content here: #PathTwitter #GIPath #BSTPath
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@MirunaPopescu13
Miruna Popescu, MD
5 months
Non-ossifying fibroma (NOF) 📈Benign, self limiting 👶🏻Skeletally immature, 2nd decade of life, M>F 🦴Metaphysis of long bones (around knee) 🩻Cortical-based, well defined, sclerotic & scalloped border, lytic, lobulated 🔬Bland plump spindle cells, storiform, scattered
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Curious to hear what the expert pathologists of the #PathTwitter family think about this case of a middle-aged F with pathologically enlarged inguinal lymph nodes. Here is one of them. No other relevant clinical Hx, no abdomen/pelvis CT available. 2nd set of images 👇🏽
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@MirunaPopescu13
Miruna Popescu, MD
2 years
What are these cells with bubbly cytoplasm called? 🤔 In which #BSTPath tumor can they be found? 🔬 Read more about it here: An organized list of all my educational pathology content can be found here:
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Middle-aged man 👨🏽 with a sharply circumscribed, greyish, elevated plaque on the lateral neck. What is your Dx? 🤔 What subtype(s) of this common non-melanocytic #dermpath lesion do you see? 🔬 Answer & a short review will be posted on KiKo, link 👇🏽 #PathTwitter #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Grossly visible cystic lesion in the pancreatic tail. Can you guess the diagnosis ❓ Answer later in the chat 👇🏽 #PathTwitter #GIPath #PancreasPathology
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Esophageal biopsy, a rare occurrence: sebaceous gland heterotopia. ➡️ Polygonal cells with clear vacuolated cytoplasm ➡️ Sometimes excretory duct lined by squamous epithelium is seen ➡️ No associated hair follicles #GIPath #PathTwitter #pathoutpic
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@MirunaPopescu13
Miruna Popescu, MD
1 year
#pathbasics 📚 #PGY1 When assessing for the presence of lymph node metastases, be sure to not confuse sinus histiocytes (1st pic) with true invasive tumor cells (2nd pic 👉🏽 in this case: LN met of an invasive urothelial carcinoma). #PathTwitter #PathX #pathresidents #GUPath
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@MirunaPopescu13
Miruna Popescu, MD
3 months
#gynpath Ovarian mass in a middle-aged F 🔬What's your differential diagnosis? #IHCPath you'd like to order? #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Liver lesion. What would be your DDx based solely on morphology? 🧐 What stains would you order? Old case. Let's get some brainstorming 🧠 started over here! Answer on @kiko4docs shortly. #PathTwitter #pathresidents #pathfellows #GIPath #foreverlearning #HEpathology
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Colon polyp. What are the findings depicted in the images? Could you name one differential diagnosis? IHC, answer & short review on KiKo, link will be posted in the 🧵👇🏽 #PathTwitter #GIPath #BSTPath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Here's an easy one. Two pictures, one organ, one diagnosis. What can it be? #PathTwitter #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Eosinophilic myenteric ganglionitis: 🤔 Rare cause of chronic intestinal pseudo-obstruction (CIPO) 👶 Most common in children 🔬 Infiltration of the myenteric plexus by eosinophils => impaired motility 📖 Some cases may show admixed T lymphocytes #GIPath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
What's going on in this duodenal biopsy? Hint: sometimes, a superficial look gives away the diagnosis. 😉 Answer & more pics: #PathTwitter #GIpath
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@MirunaPopescu13
Miruna Popescu, MD
1 year
Work's been crazy the last couple of months so I had to take a bit of a break from #PathTwitter , but here's a pretty #GIPath #Liverpath case for a neat Saturday night. What's your diagnosis? Would you order any IHC? Answer the poll 👇🏽 or scroll directly further down for answers
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@MirunaPopescu13
Miruna Popescu, MD
5 months
Junior #pathology trainee pitfall alert 🚨 1️⃣ Brunner's glands can be intramucosal, especially in the duodenal bulb 2️⃣ Crushed Brunner's glands may mimic an intra-/submucosal neural proliferation 👇🏻 #beautyintheb9 #GIPath #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
3 months
Ulcerated mass in the colon. ▶️Geographic necrosis ▶️Lots of mitoses & apoptotic bodies ▶️Sheet-like & trabecular growth ▶️Highly atypical nuclei w/ prominent nucleoli ▶️Eosinophilic cytoplasm Based on 🔬H&E morphology, what is your diagnosis? #PathTwitter #GIPath
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@MirunaPopescu13
Miruna Popescu, MD
2 months
Anorectal mucosa. It cannot get more textbook-like than this! 🔬 Curious to see what #PathTwitter thinks first. Your diagnosis? #GIPath #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
2 years
High power image of an esophageal biopsy showing lots of inflammation. Let's play a little bit of hangman. Three words to best describe these nuclei? M _ _ _ _ _ _ _ _ _ _ M _ _ _ _ _ _ _ _ _ _ _ _ _ _ M _ _ _ _ _ _ What's the microorganism causing this? 🦠 #GIPath #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
1 year
From the same repertoire of short quizes: Biopsy, stomach, antrum: 1. What's happening in this biopsy? 2. Can you name one confirmatory IHC stain? 3. What would you have to rule out? 💎 Answer & pearls will be posted in the comments. #PathTwitter #GIPath
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@MirunaPopescu13
Miruna Popescu, MD
6 months
Am I too late? 🛬 in Baltimore, MD, for #USCAP2024 🎉 Can't wait to connect with educators & fellow trainees from around the 🌎 while learning as much as possible! 🤩🔬 See you there, #PathTwitter !
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@MirunaPopescu13
Miruna Popescu, MD
2 years
35 y/o ♀️, peritoneal biopsy. What's your diagnosis?🔍 Any IHC you'd like to see?🔬 Apart from the morphological clues, are there any stains that could help us here distinguish between benign and malignant? 💡🗨️Answer and further info later in the chat #GynPath #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
2 months
Sometimes, sinonasal inflammatory polyps show this pseudolymphangiomatous pattern of stromal edema! 🙏🏻Things you learn from awesome attendings at sign-out #ENTPath #Headandneckpathology #PathTwitter #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
6 months
Had such a lovely time at the @IntSocUropath Grawitz dinner! I'm honored to have had the pleasant company of such big #GUPath names @rovingatuscap @evacomperat @daniel_berney @FalzarsMd ! Especially thankful to Dr. Fine for being so thoughtful and introducing me to people ☺️ it
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@MirunaPopescu13
Miruna Popescu, MD
6 months
Cornea. What is happening here? Hint: typically more frequent in people wearing contact lenses. #ENTPath #Eyepath #PathTwitter
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Collagenous colitis ➡️ Mild architectural distorsion (crypt atrophy, crypts don't reach the muscularis mucosae) ➡️ Thick (>10 microns) hyalinized subepithelial collagen band w/ entrapped RBCs and inflammatory cells ➡️ Expanded lamina propria (Ly, plasma cells, eos) #pathoutpic
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@MirunaPopescu13
Miruna Popescu, MD
2 years
Here's a case of solitary fibrous tumor (SFT) occurring in the central nervous system. Haphazardly arranged spindled to ovoid cells around prominent staghorn vasculature, variably collagenous stroma. NAB2-STAT6 gene fusion. +ve IHC surrogate: STAT6. #PathTwitter #neuropath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
MPNST: ➡️ Sporadic, in NF1, or after RxT ➡️Hyper- & hypocellular areas ➡️Perivascular accentuation ➡️Uniform spindle cells ➡️Sometimes fibrosarcoma-like fascicular (🐟bone) growth ➡️+/- hyalinized, myxoid stroma ➡️S100, SOX10 focal, patchy or -ve ➡️Loss of nc H3K27me3 #BSTPath
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@MirunaPopescu13
Miruna Popescu, MD
2 years
In the characteristic style of @DrBMcGinn I give you this one high-power image. What is the organ? What is the diagnosis? #PathTwitter #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
5 months
Parotid mass. Completely cystic at 🔪 🔬What's your diagnosis? #PathTwitter #ENTPath #pathresidents
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@MirunaPopescu13
Miruna Popescu, MD
5 months
Presenting a poster @ Tri State Pathology Conference in Ocean Springs, MS, then working out at the beach 🏖️🌴😎 w/ Kesley Green & Sarah Anderson in the afternoon. Great #BSTPath lecture on low-grade myxoid tumors! Excellent talk on pitfalls in #BreastPath by @fouad_boulos . It
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