Mike Petassi
@MikePetassi
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Postdoc in Greene lab @DNAcurtain @ColumbiaPS \\\ PhD from @JoePetersLab
New York, NY
Joined December 2020
RT @MobDNAjournal: Happy Transposon Day 2022! Today is the 120th birthday of Barbara McClintock, founder of the #transposon field and Nobel….
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RT @MariuszCzC: Very happy to announce our TnsB paper is out! It includes 2.7 Å cryo-EM structure of transposase bound to transposon end. W….
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RT @kellogg_liz: 🔥hot off the press 🔥 It's been an exciting few months 😊 Kellogg lab's first paper with @JoePetersLab now out in Science .h….
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RT @JoePetersLab: Happy #TransposonDay2021 from the Peters Lab at Cornell University, Barbara McClintock's training ground! .
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Congrats to @kellogg_liz and co for the first lab pre-print and very happy to be on board! More Tn7-like transposon structure and mechanism to see, this time of the #CRISPR-Cas wielding RNA-guided variety.
The @kellogg_liz lab has posted its first pre-print! Here we continue our mechanistic studies of 'jumping genes' or transposases, in close collaboration with @JoePetersLab on CRISPR-associated transposases ( Type V-K CAST elements).
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Excited to be a part of this awesome work from @shen_yao10 and @alba_guarne lab! Finally get to see this piece of the mighty Tn7 transposon!.
Incredibly proud of this structure and @shen_yao10 work. I could not have anticipated how much it would explain @j_ortega_McGill @JoePetersLab @McGillMed . Structural basis for DNA targeting by the Tn7 transposon
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Expanding our understanding of dual-pathway transposition (1 - plasmids; 2 - chromosomal attachment sites) with Tn7-like elements one family at a time. New preprint from bioinformatics wizard @PopoMicro on Tn7-CRISPR-Cas12k.
Tn7-CRISPR-Cas12K transposons categorize guide RNAs for different types of integration targets. Previously shown for type I-F3 systems. Grad student @PopoMicro shows an analogous process evolved with Cas12K systems. 1/6
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