Michael Scott Cowled
@MichaelSCowled
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Research Specialist - University of Melbourne
Joined June 2014
Happy to share the work of @RStannius who identified that Bacillus subtilis isolates lacking surfactin production have delayed biofilm formation - now published in Biofilm https://t.co/SAo2YRZjyH - @cemist_dtu project finalized at @LeidenBiology
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Proud to share our latest publication out of @cemist_dtu in Applied and Environmental Microbiology @ASMicrobiology investigating fungal chemical diversity on an unusual environmental niche: black apples. Thanks @LarsenOstenfeld, @JCFrisvad and colleagues
journals.asm.org
Microbial secondary metabolites constitute a significant reservoir of biologically potent and clinically valuable chemical scaffolds. However, their usefulness is hampered by rapidly developing...
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Check our recent publication on heterologous expression of a bifunctional enzyme
pubs.acs.org
Isoquinolinequinones represent an important family of natural alkaloids with profound biological activities. Heterologous expression of a rare bifunctional indole prenyltransferase/tryptophan...
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Our new preprint from @cemist_dtu involving @LarsenOstenfeld, @JCFrisvad and colleagues, shows the possibilities of large metabolomics datasets towards understanding the diversity and ecological role of fungal SMs in black apples
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Congratulations to @MichaelCowled1 for his elegant paper in JNP showing how dueling fungi can produce some interesting new chemistry! Thanks to John Kalaitzis, Nico Sbaraini and the wonderful team at MST. @mqnatsci @SMS_UWA @ACSPublications @pharmacognosy
https://t.co/mYFR1oamdP
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Excited to share my new paper on a suite of berkeleylactones in Journal of Natural Products @ACSPublishing and @pharmacognosy. Great collaboration between @andrewpiggott, @YitHengChooi, @HangLi13, @clmgilchrist and Ernest Lacey @mqnatsci @SMS_UWA
https://t.co/QhGeeskEJO
pubs.acs.org
Penicillium turbatum has previously been reported to produce A26771B, a 16-membered macrocyclic polyketide with activity against Gram-positive bacteria, mycoplasma, and fungi, as well as the struct...
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Was a pleasure to present my research about fungal interactions on apples at #plantMicrobeInteractions2022 @ScienceCluster @cemist_dtu
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One more article about #MicrobialCoCulture : "Mass Spectrometry Imaging for Fungal Interaction Analysis: Classic versus Imprinting Methods"
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Congratulations to Michael Cowled on his paper just published in Organic Letters unravelling the mysteries of the bacterial polyketide enterocin and revising a few structures along the way! #ozchem @MQMolSci @JOC_OL
pubs.acs.org
The tricyclic scaffold of the bacterial polyketide enterocin was recently shown to undergo stereodiversification through a series of abiotic isomerizations, described metaphorically as a “ballet of...
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Congratulations to Michael Cowled on his first paper, which describes the unusual intramolecular chemical gymnastics performed by the polyketide enterocin! @OrgBiomolChem @MQMolSci
https://t.co/PYlNrGfyUd
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