OBC
@OrgBiomolChem
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This account has been archived. Stay connected with us on https://t.co/JXp8owStcT, Bluesky and LinkedIn.
Joined March 2009
@OrgBiomolChem and other @RoySocChem journals are now on Bluesky! 🦋. You can find us there at: You can also find us on LinkedIn at:
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RT @rsc_chembio: RSC Chemical Biology and Organic & Biomolecular Chemistry (@OrgBiomolChem) are proud to support the 17th International Sym….
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🔓Don't miss #OpenAccess research in our latest issue by Gavin J. Miller, Eoin M. Scanlan & co @millerrschgroup @ScanlanGroupTCD @keelechem @TCD_Chemistry describing photoinitiated thiol–ene mediated functionalisation of 4,5-enoses. Check it out below👇.
pubs.rsc.org
The photoinitiated thiol–ene reaction is emerging as a highly efficient methodology for thioglycoside synthesis. Herein, the radical-mediated hydrothiolation reaction of 4,5-unsaturated saccharides...
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🔓Take a look in our latest issue at a paper from @ChemRmitra & co describing triflic acid catalyzed intermolecular hydroamination of alkenes with Fmoc-NH2 as the amine source. 📍@IITGoaofficial.
pubs.rsc.org
Intermolecular hydroamination of alkenes is recognized as one of the most challenging synthetic pathways for directly obtaining primary amine derivatives from alkenes. While metal-catalyzed hydroam...
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Be sure to read this review from Dong Xue et al. at Shaanxi Normal University in our latest issue covering the advances in the synthesis of bicyclo[4.1.1]octanes. Find it in full below👇.
pubs.rsc.org
The exploration of bicyclo[n.1.1]alkanes, known for their intricate chemical diversity and potential as benzene bioisosteres, has garnered significant attention over the past two decades. In partic...
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🔓Don't miss #OpenAccess research in our latest issue from Mansi Sharma & Yan Zhao @IowaStateU on the microenvironmental engineering of active sites for selective catalytic hydrolysis of acetals. Check out the full article on our website🔽.
pubs.rsc.org
Rational design of synthetic catalysts that mimic enzymes in catalysis and substrate selectivity is a long-standing goal of chemists. We report bottom-up synthesis of artificial acetal hydrolase that...
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📢Our latest issue is now online!. Check out the paper behind the front cover by Laksmikanta Adak & co @iiest_s on reusable cobalt–copper-catalyzed cross-coupling of (hetero)aryl halides with primary amides under air.
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Be sure to read research in our latest issue from Min-Tsang Hsieh & Hui-Chang Lin at China Medical University describing synthetic studies aimed at the production of the natural dye, xanthomonadin. Find the full article on our websiteđź”˝.
pubs.rsc.org
Synthetic studies aimed at the production of a natural dye, xanthomonadin 1, through the hydrobromination of a heptaene ester as a crucial step are described. The hydrobromination process using the...
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Don't miss this paper by Sébastien Fort & co @Cermav_UPR5301 @UGrenobleAlpes @UnivLyon1 on chemical modification of sialylated oligosaccharides to functionalize nanostructured lipid carriers. Check it out below👇.
pubs.rsc.org
Nanostructured lipid carriers (NLCs) are innovative lipid-based formulations made up of a carefully balanced mixture of solid and liquid lipids in their core. This unique architecture offers several...
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Check out research from @Dr_SSResearch et al. @csiriict in our latest issue describing a formal [4+1] annulation incorporating styrylogous aldol condensation to access functionalized 2-styryl-benzofurans. Read it heređź”˝.
pubs.rsc.org
Despite the well-established aldol reaction and its vinylogous variants, the styrylogous version has been scarcely reported. Herein, we have introduced a styrylogous aldol condensation reaction. A...
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Take a look in our latest issue at this paper by Zi-Wei Xi, Qiliang Yuan, Yong-Miao Shen & co reporting a photocatalytic three-component reaction for synthesis of dithio-carbamates . đź“ŤZhejiang Sci-Tech University.
pubs.rsc.org
This manuscript describes a visible light induced photocatalytic three-component reaction of an alkyl halide ([(iodomethyl) sulfonyl] benzene or arylmethyl bromide), carbon disulfide, and amine for...
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🔓Be sure to read this #OpenAccess paper from Peter Langer & co at Universität Rostock in our latest issue reporting the synthesis of 6-arylpyrimido[4,5-e]indolizine-2,4(1H,3H)-diones through InCl3-catalyzed cycloisomerization. Find it in full below👇.
pubs.rsc.org
We report the synthesis of hitherto unknown pyrimido[4,5-e]indolizine-2,4(1H,3H)-diones (indolizinouracils) and related polycondensed uracils. The synthetic strategy is based on a chemoselective C–N...
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Don't miss this review in our latest issue by Sajal Das et al. from the University of North Bengal covering the synthesis of dihydropyrimidinones via urea-based multicomponent reactions. Check out the full article heređź”˝.
pubs.rsc.org
Multicomponent reactions (MCRs) have emerged as powerful tools in organic chemistry, enabling the rapid and efficient assembly of complex molecular architectures. Urea-based multicomponent reactions...
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📢Our latest issue is now online!. Check out the paper behind the front cover by Kosho Makino, Masahiro Anada & co @musashino_univ reporting the total synthesis of breviscapin B via intramolecular dehydrative etherification.
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🔓Don't miss this #OpenAccess Review by Tetsuhiro Nemoto and colleagues on the recent advances in the synthesis of 3,4-fused tricyclic indoles since 2018👇. . 📍@Chiba_Univ_PR.
pubs.rsc.org
The 3,4-fused tricyclic indole framework is a key structural motif in numerous bioactive natural products and pharmaceuticals, thus, it has drawn much attention in synthetic organic chemistry....
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🔓Take a look at this #OpenAccess research in our latest issue from @KarlGademann & co on the synthesis of 2-acetylnoviosamine derivatives by hydrogenolytic cleavage of a spirocyclopropane. 📍@UZH_Science.
pubs.rsc.org
The preparation of a 2-acetamido derivative of the rare 5,5-gem-dimethyl-deoxy carbohydrate noviose is reported in this study. The synthesis starts from readily available N-acetyl-d-mannosamine and...
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Be sure to read this research in our latest issue from Melvin Druelinger, Kenneth J. Olejar & co @CSUPueblo on the electrophilic fluorination of cannabinol. Find it in full heređź”˝.
pubs.rsc.org
Several fluorinated cannabinol compounds (3a–g) were synthesised via an electrophilic fluorination process. This resulted in the formation of two mono-fluorinated aromatic ring products, a difluori...
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A new Review by Sumin Lee and Yong Sun Park on the heteroannulation of α-bromoacid derivatives and using them in the asymmetric synthesis of various heterocycles has just been published, read it here👀. . 📍Konkuk University.
pubs.rsc.org
α-Bromoacid derivatives are configurationally labile under various conditions, and the dynamic resolution of them has been recognized as an effective strategy in asymmetric synthesis. This article is...
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Don't miss this paper in our latest issue by Min Zhang, Changsheng Yao et al. from Jiangsu University reporting the synthesis and antifungal activity of novel indolespiro bicoumarins. Check it out heređź”˝.
pubs.rsc.org
This article reports a spiro cyclic system that contains an oxoindole and two coumarin rings. Dozens of compounds with this structure have been synthesized, via a facile three-component reaction of...
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🔓Check out this #OpenAccess research by @UnsworthChem, Gideon Grogan & co @ChemistryatYork in our latest issue describing cyclopropanation reactions by a class I unspecific peroxygenase. Read it in full below👇.
pubs.rsc.org
Non-natural biotransformations, such as alkene cyclopropanation through carbene insertion, have been demonstrated for the hemoproteins cytochrome P450 and myoglobin, but have not been investigated...
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