MERINO Trial
@MerinoTrial
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RCT of Meropenem vs. Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Due to ESBL-producing E.coli and Klebsiella spp.
Brisbane, Queensland
Joined June 2015
We will be presenting the headline @MerinoTrial results in late breaker clinical trials session @ECCMID in Madrid - looking forward to sharing the results after years of hard work from many investigators in 9 countries @UQMedicine @UQ_News @ASIDANZ @davidantibiotic @padstamundo
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π₯π₯NEW π₯π₯ My new post a great collaboration w the amazing @IDstewardship Year In Review: Topβ¨ Non-COVID Infectious Diseases Articles Of 2021 18 high quality π RCTs 6 RCTs @NEJM
#Shorterisbetter
#IDTwitter #MedEd #TwitteRx #ASPchat #SoMeDocs Othersπ€ https://t.co/wJtdjYJ0Gf
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An @ASIDcrn clinical trial showing how future Trials for Resistant Gram Negative bacteria should be performed @MerinoTrial @davidantibiotic @padstamundo @IDWeek2021 @LodiseThomas
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A5. MERINO Trial @MerinoTrial was very helpful and well done. Answered real world, ID-related question/debate, low risk of big pharma bias (both generic), and changed my practice re: optimal Abx Rx for CRO-resistant E.coli/Klebsiella bacteremia. #ASPchat
https://t.co/ozmIN8LJlw
jamanetwork.com
This noninferiority trial compares the effects of piperacillin-tazobactam vs meropenem on mortality in patients with bloodstream infection caused by ceftriaxone-nonsusceptible Escherichia coli or...
Q5. ππ Whatβs one of your favorite antimicrobial-related articles of all time?Β #ASPchat Β―\_(γ)_/Β―
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Nice summary from @adm_stewart - lead author of the MERINO-2 trial, now published in OFID @IDSAInfo which tackles the thorny issue of PTZ for AmpC producers @UQMedicine @MerinoTrial
The recently published MERINO-2 trial in OFID is a pilot clinical trial which compares the use of piptaz to mero for treatment of bacteremia due to AmpC-producers. Correct interpretation of data and take-home messages are of great importance 1/
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ππ₯π₯ MERINO-2 #OFID Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp or Serratia marcescens https://t.co/6exOKwkGB9
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MERINO-3 Trial Protocol now published: Ceftolozane-tazobactam versus meropenem for definitive treatment of bloodstream infection due to... - https://t.co/zXs2CFcsqz
#ScholarAlerts @MerinoTrial @davidantibiotic @adm_stewart
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New! ππ₯³ Itβs less about COVID than you might think. https://t.co/jhoCuXC8g0 Credit for this list goes to @ABsteward!!!
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Clinical effectiveness of new antibiotics vs carbapenems for cUTIs @jasonroberts_pk @padstamundo @Yukie40899965
healio.com
The clinical effectiveness of new antibiotics was similar compared with carbapenems for treating complicated UTIs, although the new treatments demonstrated a better microbiological response, resear...
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More sheep in the paddock
Out in CID - Association between minimum inhibitory concentration, beta-lactamase genes and mortality for patients treated with piperacillin/tazobactam or meropenem from the MERINO study @merinotrial @padstamundo
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Dr. Tamma: MERINO-2 is a pilot RCT comparing pip/tazo vs meropenem for BSI 2nd to AmpC producers (species &genus details in slide @jpogue1 π) Enrollment completed, awaiting results. @IDWeek2020 #idweek2020
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And here is my #top10papers in ID for 2019 in one slide if you can't be bothered reading the whole thread #IDtwitter. Happy new year!
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Coming very soon from @padstamundo and @MerinoTrial - a new RCT of #cefiderocol for hospital-acquired BSI, especially in settings of MBLs and other forms of carbapenem resistance.
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Interesting point-counterpoint discussion on the implications and interpretation of @MerinoTrial @davidantibiotic
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Lots of reference to the merino trial! Changing practice all around the world! Very proud Australian @MerinoTrial @padstamundo #ECCMID2019
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@victoriahall26 @ESCMID @TAEscmid A really healthy trend in ID at the moment, with the OVIVA, @MerinoTrial, #camera2, #POET, 7 v 14 d for GNB, etc. ...Asking a question and answering it, with relatively limited funding, it seems!
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For anyone going to #ECCMID2019 we will be presenting some additional @MerinoTrial data on clinical outcome related to MICs (using BMD) and AMR genes. @padstamundo @davidantibiotic
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Best of 2018 Clinical Trials in ID According to my followers. @MerinoTrial. Congratulations @padstamundo and @davidantibiotic for a great study. More to expect in 2019. MERINO 2
Which RCT/study of 2018 you believe is the most impactful/Practice changing in ID π€ @NEJM @JAMA_current @MerinoTrial @IDSAInfo @padstamundo @davidantibiotic @accpinfdprn
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β¦@JWatchβ© Top 10 Infectious Diseases articles of 2018 as selected by the editors β¦@Armstrwsβ© β¦@RMKGandhiβ©
jwatch.org
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