Very happy to see our paper “Cancer-associated USP28 missense mutations disrupt 53BP1 interaction and p53 stabilization” featured in the @NatureComms Editors’ Highlights (Cancer). Many thanks to the editors for highlighting our work. https://t.co/naUqEO6V4g

Our study on the mitotic stopwatch is out. We demonstrate that USP28 interacts with 53BP1 to stabilize p53 and show that cancer cells frequently harbor mutations that impair stopwatch assembly, thereby suppressing the mitotic stress response. https://t.co/p4O1z8dea8

Congratulations to Hamzah for receiving the EMBO Molecular Medicine Poster Prize at #MBSJ2026. Well deserved! https://t.co/XoPOepBTZm

We’re recruiting a Postdoctoral Researcher at @OISTedu (Okinawa, Japan) to explore how mitotic stress shapes aging. If you’re excited about cell biology, aging, and mechanistic discovery, we’d love to hear from you. More info: https://t.co/lEdRcYbnGA

Join us for the #CellDivision2026 meeting in Okinawa. Abstract Submission Deadline: Nov 3. https://t.co/uyklm01xC9

Join us for the Cell Division Meeting in the Pacific Island setting of Okinawa. Hosted at OIST, this symposium brings together leading researchers to explore emerging roles of the cell cycle in development, cancer, and aging. Registration now open: https://t.co/ATGg9TYEjN

@biorxivpreprint @Midori_RuruOta

Excited to share our new preprint on @biorxivpreprint! We show that USP28 mutations found in cancer block its interaction with 53BP1, disrupting p53 stabilization. Check out the full story... https://t.co/t7XbfY3cID

Check out our review on "PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential". Everything you need to know about centriole duplication, mitotic stopwatch and TRIM37-mediated cancer-specific vulnerabilities. @Midori_RuruOta https://t.co/tm0BWhauuj

For all cell biologists: join the conference organized to celebrate 50 years of German Society for Cell Biology! https://t.co/FMSFjoRNxq Registration is open! See you in Heidelberg. #DGZ50

We wish you Happy Holidays from Okinawa!

A prolonged mitosis is characteristic of defects that drive genome instability. What are the underlying causes and broader implications of prolonged mitosis? Check out our review... https://t.co/yFjjnyUKhG

Interested in Base Editing and Genetic Screening? Check out our method chapter: https://t.co/zeCQIETlSV Esther Ng did an excellent job developing these methods in our lab. The constructs will soon be available on @Addgene Many thanks to @OISTedu for supporting open access!

We are happy to share our review on the 53BP1-mediated activation of the tumor suppressor p53. We summarize the cell cycle-depend functions of 53BP1 during mitosis and interphase and address its role in maintaining a healthy tissue. https://t.co/sA1ZkYjGAP

We are looking for faculties interested in #Energy and #Sustainability broadly defined.

Big thanks to all @DKW_2024 participants for excellent science, engaging conversations, and mountain excursions! We hope to see everyone in Oxford in 2027. Thanks also to our generous sponsors @EMBOevents @Co_Biologists @eLife @Chromosoma_EB @snsf_ch @UNIGEnews @EMBO

Our paper "Control of cell proliferation by memories of mitosis" is out @ScienceMagazine. We show that cells can detect and memorize defects in mitosis to eliminate potentially damaged cells. @OISTedu @Meitinger @oegemadesai_lab

🔬Groundbreaking research by OIST Cell Proliferation and Gene Editing Unit and collaborators show how cells become ultimate protectors against cancer!🧬Did you know cells sense defects by measuring the duration of #mitosis? @MeitingerOhta @oegemadesai_lab

Our new paper is out in #NatureAging ! Cell membrane damage induces senescence! 1st authors --> @kouchocolate @OIST_KonoLab @apple_hani https://t.co/jFQHJmzJdN

分からない病気は、治すことができません。 @MeitingerOhta’s Unitでは、細胞分裂はどのように正しく行われるのか、うまくいかなかった場合は何が起こるのかを研究。#がん の新たな治療 標的を探しています。#NewFacultyOfOIST @Meitinger @Midori_RuruOta 記事はこちらから⬇️