Lynn Megeney
@MegeneyLab
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We study the fascinating non-lethal biology of caspase/metacaspase proteases ☠️. We are also interested in the molecular cues that manage cardiac remodeling🫀
Ottawa Hospital Research Inst.
Joined March 2023
RT @Matt_Muscle_Guy: Congrats to @LorsonLab and colleagues for their new @hmg_journal paper: Novel neurofilament light (Nefl) E397K mouse m….
academic.oup.com
Abstract. Charcot–Marie-Tooth (CMT) is the most common hereditary peripheral neuropathy with an incidence of 1:2500. CMT2 clinical symptoms include distal
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one of the most interesting papers on muscle biology in decades. a challenge to the satellite cell hypothesis!!!!. Muscle growth by sarcomere divisions | Science Advances
science.org
When muscle cells enlarge during developmental growth, they divide their contractile sarcomeres into daughter sarcomeres.
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RT @Matt_Muscle_Guy: New @NatureMedicine paper: AAV mini-dystrophin gene therapy for Duchenne muscular dystrophy: a phase 1b trial. #DMD ht….
nature.com
Nature Medicine - In the primary report of a phase 1b trial, adeno-associated virus gene therapy with fordadistrogene movaparvovec in patients with Duchenne muscular dystrophy was well tolerated in...
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RT @Matt_Muscle_Guy: Interesting new #JACC paper: Long-Term Dystrophin Replacement Therapy in Duchenne Muscular Dystrophy Causes Cardiac In….
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very cool paper from Assaf Vardi's group on metacaspase function in diatoms. Metacaspases mediate thermotolerance of diatoms following marine heat waves | bioRxiv
biorxiv.org
### Competing Interest Statement The authors have declared no competing interest. Israel Science Foundation, 749/24
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RT @chang_natasha: Happy to share that our single-cell analysis of muscle stem cells in two DMD models is now published in Cell Death & Dis….
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RT @Transactivator: Happy to share our new paper demonstrating optimization of base editing to correct the lethal ACTA2 R179H mutation in h….
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Great career perspective in Nature Metabolism from Dr Ben Weaver
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RT @WeaverScience: It was a lot of fun today getting to talk with the students about life and career challenges! Thanks Arnaldo and Leah f….
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RT @wc_ratcliff: New major paper from our lab: Interested in learning more? Come read about it at BlueSky, the new….
nature.com
Nature - In the Multicellularity Long Term Evolution Experiment, diploid yeast evolve to be tetraploid under selection for larger multicellular size, revealing how whole-genome duplication can...
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RT @joey_ghersi: 🚨 The Ghersi Lab is Hiring! 🚨. If you're passionate about hematopoietic stem cells, developmental biology, and cutting-….
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RT @OttawaHospital: On this International Day of Women and Girls in Science, help us celebrate our remarkable researchers who are changing….
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RT @tpulinil: Excellent meeting of #IHCVS2025 at @UHCancerCenter. Thrilled to network with colleagues in #cardiovascular sciences. A trea….
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RT @lusciousleah73: F$^% Tourettes, I know this story too well with my own son. What happens when the drugs stop working and the tics are c….
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RT @PhysInHistory: We know that the only way to avoid error is to detect it and that the only way to detect it is to be free to inquire. An….
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RT @amacklin10: Chasecation Photo #4: May 19th. After the supercell near Hays, I dropped south to Great Bend KS for the oncoming derecho.….
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RT @Health_PEI: PEI is the only province in Canada to recognize family medicine as a specialty and family physicians here are among the hig….
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