"Synthetic biology is among the most hyped research topics this century, and in 2010 it entered its teenage years. But rather than these being a problematic time, we’ve seen synthetic biology blossom and deliver many new technologies and landmark achievements." Nat. Commun. 2020

The second decade of synthetic biology: 2010–2020 | Nature Communications

@scrippsresearch • Redesign of sugar structures to improve drug properties. • Development of next-generation therapeutics, including advanced vaccine adjuvants (e.g., enhancing immune responses in vaccines), cancer therapies, and safer treatments overall. Grok Nat. Commun. Vol. 11, 5174, 2020

Lecture Details: Description and Key Focus Yuzhong Liu's lab leverages synthetic biology (combined with metabolic engineering, synthetic chemistry, and analytical tools) to decode and manipulate these sugar decorations Grok AI @scrippsresearch

Predicting when symptoms of Alzheimer's disease will occur with elevated p-tau217 blood test and a person's age, even 20+ years in advance @NatureMedicine https://t.co/e81z4Cgwyo

Modular, One-pot, Cu-catalyzed chemistry 🔥 Trifluorodiazoethane → CF₃-β-lactams via in situ nitrones + Kinugasa reaction. Broad scope, modular, and synthesis-ready 🧪✨Further exteneded to phosphonate-β-lactams from @CSIR_CDRI @JOC_OL 🔗 https://t.co/Cu5uGpCyVd

The sweet side of drug discovery: How sugars can help shape the future of medicines Yuzhong Liu, PhD Assistant Professor, Department of Chemistry https://t.co/1cdtoiWlp6 @scrippsresearch

Meaning of each term for Non-Experts Grok 💯 Key Findings & Terms from the Study - Pancancer - Differentially methylated regions DMRs - 5' end motifs - Fragment lengths - Nucleosome footprints - Integrating methylome and fragmentome features - Validation - Ressource/Compendium

Dear Grok AI Meaning of each term for Non-Experts Thanks Core Concept: Cell-free DNA Main Techniques and Features Analyzed - Methylation/Methylome - Fragmentation/Fragmentome - Profiling - cfMeDIP-seq

Show Authors A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection Nature Cancer Feb 2026 Key Highlights from the Abstract - Challenge addressed - Dataset - Methods - Findings - Validation - Resource Thank you Grok AI

A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection Nature Cancer Feb 2026 Key Highlights from the Abstract - Challenge addressed - Dataset - Methods - Findings - Validation - Resource Thank you Grok AI

"Here we collated 1,074 cfMeDIP-seq profiles across 9 studies, comprising CANCER SAMPLES from 11 CANCER TYPES, carriers of Li-Fraumeni syndrome and healthy controls." "We developed a UNIFORM COMPUTATIONAL WORKFLOW to mitigate technical and biological confounders across cohorts."

"The referenced study is a paper published in Nature Cancer on February 19, 2026, titled "A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection". Grok AI

The post from @LungCancerEu highlights a significant recent advance in multi-cancer early detection (MCED) using liquid biopsy approaches, specifically blood-based tests analyzing cell-free DNA (cfDNA).

The 384 de novo designed proteins in the study "Large-scale exploration of protein space by automated NMR" (bioRxiv Feb. 16, 2026) are described as small-to-medium sized (around 50-80 residues), monomeric proteins suitable for high-throughput NMR characterization." Grok AI

Large-scale exploration of protein space by automated NMR Hiller and co-workers 2026 https://t.co/Yz7u6ehIzB…

‼️Major step forward for multicancer blood testing. A new Nature Cancer study shows that layering fragment patterns on top of DNA methylation makes these blood tests significantly more accurate. At very high specificity, detection improved from 63% to 77%. #Lungcancer survival

Overall Workflow and Impact The three components form a closed-loop, scalable platform: - In silico - Automated-wet lab - Standardized NMR Why This is Transformative Grok AI

Secondary and tertiary boron compounds can be synthesized from simple alkenes via MHAT. Please check our new paper in @JOC_OL. https://t.co/Z0CBj7Rv26

Dear Grok AI "Step-by-Step Breakdown of the Methodology described by Hiller and co-workers" Thank you very much! 1. Generative de Novo Protein Design 2. Automated High-Throughput Protein Production 3. Standardized NMR Spectroscopy