Our work interrogating chondrocyte mechanotransduction and co-opting TRPV4-signaling to develop mechanogenetic cartilage is out today in @ScienceAdvances - great team effort on this one with @LPferdehirt and the @Guilak_Lab crew! @Farsh_G https://t.co/LQcHKmVW1p

Is there anything TRPV4 can't do? Our paper just out in @StemCellsJournl by Vince Willard shows that #TRPV4 is not just a marker of chondrogenesis, it also regulates it in #iPSCs! w/ Holly Leddy, Daniel Palmer, Chia-Lung Wu, & Wolfgang Liedtke @Regeneron https://t.co/ydVXNcPP19

Can cells be rewired to deliver on-demand drugs that fight fluctuating #inflammation? We bioengineered anti-cytokine implants using #CRISPR #synbio that mitigated #arthritispain, #jointdamage, bone erosion and inflammation in mice: https://t.co/MCoNLJV324 @Farsh_G @WUSTL_Rheum

New disease-aggravating feed-forward mechanism of osteoarthritis https://t.co/PnqGIugtp0

Wonderful review led by @mollyklimak is now out - surveying the latest advances in immunoengineered technologies for treating arthritis.

And here is the press release on @WhasilL's paper on Piezo sensitization in chondrocytes by IL-1! Excited to see where she next takes this project in her lab! https://t.co/QoYZOv0PfJ

Great new paper by @WhasilL showing how inflammation provokes cellular mechanosensitivity through Piezo1. Great working with Wolfgang Liedtke’s lab, @mcnultylab, @AliSavadipour, @Farsh_G

OK I found my words. I am howling with rage tonight at the rising tide of violence and hate crimes directed towards Asians in America, punctuated by the horrific shootings yesterday in Georgia at 3 Asian-owned business that claimed 8 lives, including those of 6 Asian women.

Come join us! InPrint is a great opportunity to advance your scientific communication skills while helping out the @WUSTL research community. @WashUBME @washu_ortho_res @wustlcrm

#POSTDOC position still exists in @McAlinden_Lab! Exciting, interesting projects. #MSK basic and translational studies. Great #training and #mentorship opportunities. Pls email or DM if interested. Come join us. #academicfamily

In the latest edition of @NIH Research Matters: Engineered cartilage produces anti-inflammatory drug

Thank you @NIH for highlighting our work!! @MaybeItsBob @Farsh_G excited to continue to see the #mechanogenetics love on Twitter

Thanks for the highlight of mine and @MaybeItsBob #mechanogenetics work @shrinershosp @ShrinersStLouis @Guilak_Lab @Farsh_G

At NIH, @KizzyPhD says: "When we got those sequences, because we knew how to make that protein as a very good vaccine, we did that really quickly over the weekend." @POTUS: "Over the weekend." @KizzyPhD: "Over the weekend. You know something about working on weekends, right?"

Tomorrow! Bioengineering and pregnancy webinar with @alysrclark and @kyokoyoshida -- details at

Please Re-tweet! We're recruiting Postdocs - biologists & bioengineers - join a great team & live in the DC area! Mechanobiology of embryonic tendon development; therapeutics for adult tendon regeneration; interventions for birth defects. Click on ad for details. Thanks!

Incredible study by @NHarasymowicz getting at the whodunnit of obesity induced inflammation - excited to see where this work goes!

Our lab is recruiting two post-docs on two newly funded projects on primitive collagens and ECM-based regeneration. Exciting collaborations with Dr. Eiki Koyama, @DymentLabPenn, @MauckLab, @HeoLab .

Senior postdocs, brand new PIs and junior faculty in ortho - we're creating a community to help you navigate this unique stage of life! Join us at #ORS2021 for a virtual Meet & Greet: 2/15/21 at 5pm PT/8pm ET @jaymilanpatel @mikehastPhD Learn more @

#WashUMed researchers led by @Farsh_G have engineered cartilage cells to produce an anti-inflammatory drug in response to mechanical stress associated with movement and weight-bearing. Published in @ScienceAdvances. @Guilak_Lab https://t.co/Mn83xpt75U

Synthetic biology & tissue engineering came together to generate genetically engineered cartilage that can deliver an anti-inflammatory drug in response to movements that put stress on joints. #synbio @Guilak_Lab @MaybeItsBob @Farsh_G https://t.co/ClEDn4YFms