Lara Pferdehirt
@LPferdehirt
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Consultant at Bain & Co. BME PhD in Guilak Lab from WashU in St. Louis. @ORSSociety Social Media Committee #ORSSMC. Tweeter in Chief of @Guilak_Lab
St Louis, MO
Joined February 2017
How do you combine #synbio and #circadianrhythms to protect #cartilage? Check out our work in @ScienceAdvances on clock-preserving circuits that maintain circadian rhythms in the presence of #inflammation - with @annardamato & the Herzog and Meng labs! https://t.co/UYswAEFsUU
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Just in case you thought he was done with just one national academy…today our fearless leader @Farsh_G got inducted into the @theNAMedicine!!! #NAE #NAM
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Thrilled to have met the new @RiceUniversity President @RDesRoches at the #NAE meeting this year! Congratulations on your induction to the class of 2020! @theNAEng
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You're going to have to tune into @handpodcast if you want to learn @Farsh_G's answer to this pressing question in this sneak peak!
Sneak peak of a new episode dropping tomorrow! Learn from @Farsh_G - one of the GOAT's of orthopedic research - about mentoring and navigating career pivots. Can't miss this one! @Congenitalhand @ChrisDyMD @Guilak_Lab @WUSTLortho #handsurgery #orthotwitter
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Please join me June 13, 12pm CT for a webinar on my favorite topic: “I was trained how to do everything but run a lab!” The lecture is free on the AOCConnect platform. Just register (no cost) as a researcher: https://t.co/u5zNm4F72U & the info will be sent from there. (1/3)
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Synthetic gene circuits to support daily #rhythms in cartilage -- a strategy for creating cell-based therapies to preserve the #circadian #clock in the presence of inflammation. @ScienceAdvances ( https://t.co/TUQffv3q1v)
@Farsh_G @ErikHerzog @LPferdehirt
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Sometimes recapitulating a system in culture teaches you something new! @LPferdehirt and colleagues engineer mouse iPSCs to create chondrocytes that resist inflammation-induced clock disruption and loss of matrix production.
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Dr. Lara Pferdehirt (@LPferdehirt), @AnnaRDamato, and Dr. Farshid Guilak's group (@Farsh_G) at @WUSTLmed developed genetically engineered #cartilage from #iPSCs capable of preserving the circadian clock 🕐 in the presence of #inflammation. Read more 🔗: https://t.co/hz3AqN94Hz
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Another fun result in @LPferdehirt's & @annardamato's study - stem cells (iPSCs) don't have a circadian rhythm, but as they differentiate to chondrocytes, they develop a 24 hr clock, similar to primary chondrocytes (which will continue to cycle for over a week outside the body!)
How do you combine #synbio and #circadianrhythms to protect #cartilage? Check out our work in @ScienceAdvances on clock-preserving circuits that maintain circadian rhythms in the presence of #inflammation - with @annardamato & the Herzog and Meng labs! https://t.co/UYswAEFsUU
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So excited for first of several studies in our new area of synthetic #chronogenetics! Amazing work by @LPferdehirt & @annardamato in collaboration with @ErikHerzog & the Meng lab to show that we can use #synbio to prevent loss of circadian rhythms! @ShrinersStLouis @wustlcrm
How do you combine #synbio and #circadianrhythms to protect #cartilage? Check out our work in @ScienceAdvances on clock-preserving circuits that maintain circadian rhythms in the presence of #inflammation - with @annardamato & the Herzog and Meng labs! https://t.co/UYswAEFsUU
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Are you ready to learn about chronogenetics? Read about this cool collaboration with @Farsh_G, @annardamato, @LPferdehirt et al. engineering cells to protect against #osteoarthritis.
How do you combine #synbio and #circadianrhythms to protect #cartilage? Check out our work in @ScienceAdvances on clock-preserving circuits that maintain circadian rhythms in the presence of #inflammation - with @annardamato & the Herzog and Meng labs! https://t.co/UYswAEFsUU
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#ManuscriptMonday an absolute must-read for anyone interested in #fibrosis by @LPferdehirt @Guilak_Lab @Farsh_G @wustlortho @washubm @TheRealJHuard @SPRIVail #ORSSMC #orthoresearch #ORSNation
onlinelibrary.wiley.com
Gene-edited muscle-derived stem cells sense the presence of TGF-β1, a driver of fibrosis, and produce decorin, an antifibrotic therapeutic, in an autoregulating manner. These decorin-producing stem...
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Was trying to work my way to a paid trip to go skiing in Vail, but ended jp with a cool collaboration with @SPRIVail and a paper, can’t complain!
#ManuscriptMonday an absolute must-read for anyone interested in #fibrosis by @LPferdehirt @Guilak_Lab @Farsh_G @wustlortho @washubm @TheRealJHuard @SPRIVail #ORSSMC #orthoresearch #ORSNation
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How well do you know the @ORSsociety team? Be sure to read this week's ORS Connect to get to know Natasha! Her positive energy is contagious, and we greatly appreciate her support! #ORSSMC
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Feeling withdrawal from #ORS2022? Wishing you were still able to build your network and make new connections? Keep the momentum going by joining the @ORSsociety mentoring program. Deadline to apply is Feb 18! #ORSSMC #orthoresearch
https://t.co/urvapKx5JC
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How can you help make #ORS2023 even better than #ORS2022? Be sure to fill out the annual meeting survey (check your email!). This input will help guide planning of future ORS meetings. #ORSSMC @ORSsociety
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