Marketa Novotna
@MarketaNovotna6
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@wellcometrust Postdoctoral Researcher at @UoDLifeSciences | David Horn's group | interested in histones in Trypanosoma brucei
Dundee, Scotland
Joined March 2020
Coming up: Postdoctoral fellowship mini-workshop as a part of the SPPIRIT Forum series. EMBO, Marie Curie, and Wellcome Early Career fellows will share their advice on fellowship applications. Join us at 12 noon on Thursday 14th November! Register at
docs.google.com
SPPIRIT would like to invite you to join our series of meetings - the SPPIRIT Forum! The forum is a platform where we will discuss parasitology, funding applications, experimental methods, and other...
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Incredibly proud to share that our work on Cryptosporidium Oocyst Wall Proteins is published in @PLOSPathogens
https://t.co/khGAl0PRV3 Led by previous PhD student @BacchettiRoss and carried on by current PhD student, Sarah Stevens.
journals.plos.org
Author summary Infection with Cryptosporidium causes diarrhoea, which can be fatal for malnourished children or people who are immunocompromised. There is no vaccine or effective medicines available...
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Another piece of the VSG expression control puzzle: Active VSG transcript is required for allelic exclusion, acting as both, non-coding and coding RNA. Elegant study by @EscrivaniD included depletion of active VSG transcript and the use of VSG transgene. https://t.co/QTnvgmRpXC
academic.oup.com
Abstract. Bloodstream-form African trypanosomes display antigenic variation. This requires mono-telomeric but switchable expression of a Variant Surface Gl
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I don’t know who needs to hear this but your PhD doesn’t need to be perfect. It just needs to be finished.
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Save the date and join us on 22nd of August for a parasitology journal club, 1st session of the SPPIRIT Forum series.
We would like to invite you to join our brand new SPPIRIT Forum! This series of online meetings aims to bring parasitologists together to discuss science, funding opportunities, etc. For more info, join our mailing list:
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Nice to have been involved in this study led by @MarketaNovotna6. Super elegant application of CRISPR precision editing! Precision-edited histone tails disrupt polycistronic gene expression controls in trypanosomes | Nature Communications
nature.com
Nature Communications - Transcription in trypanosomatids, such as Trypanosoma brucei, is predominantly polycistronic and involves unconventional RNA polymerase II promoters. This study uses...
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It was great to work on it with @JoanaRCF, who was a great mentor to me during my PhD.
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I used inducible CRISPR/Cas9 to make Trypanosoma brucei cell line that allowed me to edit originally muti-copy histone gene. We uncovered a novel role of H4 histone tail in gene regulation. I had a great time working on this exciting project! https://t.co/9Hp0mUqrq2
nature.com
Nature Communications - Transcription in trypanosomatids, such as Trypanosoma brucei, is predominantly polycistronic and involves unconventional RNA polymerase II promoters. This study uses...
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RA job open in Andrew Maclean's new lab at @edin_EID #parasitology #jobs @SPPIRITnetwork @BSPparasitology
https://t.co/AgtiZ9OZPG
elxw.fa.em3.oraclecloud.com
A research assistant position is available in the research group of Dr Andrew Maclean (Institute of Immunology and Infection Research, University of Edinburgh). We are looking for an enthusiastic...
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I am delighted that the preprint of my PhD work is out! We used Cas9-based method for editing histone H4 gene in T. brucei to see the roles of H4 modification in gene expression control. A big thanks to @JoanaRCF who was a fantastic mentor during my PhD
biorxiv.org
Transcription of protein coding genes in trypanosomatids is atypical and almost exclusively polycistronic. In Trypanosoma brucei , approximately 150 polycistrons, and 8000 genes, are constitutively...
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Applications for awards to attend the 2025 MPMXXXVI meeting are now open - details, deadlines and application information below. Please share with anyone interested.
Do you work on parasites and reside in an LMIC? Consider applying for a 2025 MPM LMIC award. The deadline is March 3rd, 2025—details on the website. https://t.co/fsZx5aOho8
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In our January issue: TrendsTalk highlighting @SPPIRITnetwork, a network connecting #Scottish #ECRs in #parasitology, authored by R.C.S. Edgar, J. Hanna @MarketaNovotna6 @MartaCampillo_ @MukulRawat90 @shikha_tweets @Frank_Venter & M.C. Ridgway. https://t.co/d3dknFMILi
Our 2025 January issue https://t.co/cbi2BSoKXJ reviews type2 immunity in gut homeostasis & Plasmodium transmission, malaria elimination in Thailand, male & female schistosome interactions, placental malaria & CSP-specific immunity, community ecology of invasive ticks, & more.
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cc to non-bskiers - Job alert! Interested in weird biology of malaria parasites? Inducible genetic screens? single-cell RNAseq? Come postdoc with us - https://t.co/1Bru2b1kpB ! International applicants or just finishing up their PhD, both welcome!!
jobs.gla.ac.uk
Job Purpose We are seeking to recruit a motivated and creative Research Assistant/Associate (postdoctoral researcher) to work within an MRC-funded research programme https://gtr.ukri.org/projects?...
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Have you finished your #PhD and are interested in exploring how #parasites cross the vasculature to colonize tissues? Do you fancy #surfing? Join us in #Lisbon at @GIMM_Institute , where science meets quality of life. @parasitesrule @CaixaResearch @JobsScience @EMBO
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If you are looking for a postdoc in tryps, check out this recent vacancy in the Faria lab in York. Great opportunity to work with a supportive mentor using cutting-edge techniques to address exciting questions.
Are you interested in #trypanosomes #biomolecularcondensates and/or #geneexpression? We are looking for a highly motivated postdoc to work with with us in the beautiful city of York! @UniOfYork @YBRI_UoY @BiologyatYork Please RT! https://t.co/qaSLw5b1p0
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📢Postdoc opportunities: we are seeking two experienced and motivated researcher to join MRC and WT funded projects on mitochondrial biology in Plasmodium and Toxoplasma shared between Glasgow and Helsinki. #postdoc #mitochondria #structure #parasite
https://t.co/pXRmzW5M8B
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PhD opportunities with many of our Centre members. Come study with us https://t.co/u2Kj2fR6A7
https://t.co/nISNqFTMHH
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Available PhD position @DiMeN_DTP @The_MRC How does #SUMOylation shape nuclear organisation? How does that impact #trypanosome immune evasion. If you find this an exciting topic, join us! @BiologyatYork @YBRI_UoY & @UoDLifeSciences For more information, contact me!
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Funded PhD available with us, @martllewellyn and James Cotton @UofGSii @UofGSBOHVM @WCIPGLASGOW to study genome replication and (in)stability across diverse kinetoplastids. Applications (via FindaPhD) taken from Nov 1st - Jan 12th. Enquiries welcome. https://t.co/Cow8ywjqD5
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Interested in gene expression control in trypansomes? See a new paper from the Horn group that describes cis-regulatory UTR sequence ‘code’ in T. brucei for the fist time, shedidng some light on how expression is regulated in an organism with constitutive trasncription.
Read the latest paper from @UoDLifeSciences @WCAIRDundee Anna Trenaman, Michele Tinti, Richard Wall & David Horn in @NatureComms
https://t.co/QSzGULJeIn
@BSParasitology@AmSocParasit @wiparasitology #trypanosomes
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