Huge congrats to @Karyna_mi for her paper published today in @ScienceMagazine! She found that the hippocampus is really important for a key strategy we use to make decisions called hidden state inference! 🧪 🧠 https://t.co/6RgR5Iu6FL 1/7

New preprint out! We developed a behavioural platform for the kinematic analysis of skilled whole body behaviour. Very fun collaboration with Christopher Black, Liam Browne and Rob Brownstone.

looking forward to speaking at KCL on thursday!

Come use a combination of neural network and reinforcement learning approaches to tease apart how the brain supports motor adaptation with us @Ian_Duguid, Angus Chadwick and @eckstein_maria 🧠🤸

Want to start your own lab at UCL? Then check out this opportunity. I went through the process a few years ago and can only recommend it! A fantastic place to do science, especially because of amazing colleagues and collaborators.

@RuedigerSarah the role will also allow you to join the amazing UCL neuroscience community @uclnpp @uclbiosciences - with hundreds of world class neuroscience research groups, all extremely collaborative and supportive, with an amazing mentorship program - all together an amazing opportunity!

Highly recommend @RuedigerSarah lab - asking really exciting and important qs about how we convert sensation to decision making - using all the most fun tech! I did both PhD and postdoc in a new lab - its an amazing environment to do great science with amazing mentorship. apply!!

Join our team! We're investigating how the visual cortex interacts with subcortical structures like the Superior Colliculus and Basal Ganglia to shape sensory processing and behavior in health and neurobehavioral disorders. 🔬👁️ #NeuroscienceJobs #Neuroresearch @uclnpp

@Karyna_mi @ScienceMagazine congrats @Karyna_mi! and important to note this is an excellent collaboration between us, @WilbrechtL , @docqhuys and @gabigregoriou, albert Qu and @AlizeeKastler! team science!

@Karyna_mi @ScienceMagazine We are now going to use these findings to investigate how these changes in hippocampal function might lead to the increased risk of mental illness, and how we might go about designing new treatments to help reverse this increased risk in the future 7/7

@Karyna_mi @ScienceMagazine We are excited about this is bc. patients with mental illness inc schizophrenia or depression are often impaired this type of decision making, and have alterations in their hippocampus. We link these - we show that you need the hippocampus for solving these problems! 6/7

@Karyna_mi @ScienceMagazine She also found that the way the hippocampus supports hidden state inference is similar to how it supports spatial navigation and memory – which means we can use decades of beautiful work (a lot from UCL!) studying spatial navigation to help us better understand this process 5/7

@Karyna_mi @ScienceMagazine @Karyna_mi found that the hippocampus is key for this process - mice without a functioning hippocampus couldn’t use hidden state inference anymore. 4/7

@Karyna_mi @ScienceMagazine However, we often notice things: how quickly they respond, short messages, if they’re using emojis. We use these clues to make a guess about how our friend is feeling. e.g. if they reply with one-word answers we will infer they’re feeling sad – this is hidden state inference! 3/7

@Karyna_mi @ScienceMagazine But what is hidden state inference? Imagine you’re texting with a friend. Because you can’t see them in person, you can’t directly tell if they’re happy or sad. This is because their emotions are hidden - you can’t observe happiness or sadness directly through text messages. 2/7

Pleased to announce I've received an Early-Career Award from @wellcometrust. Excited to spend the next 5 years studying the neural circuit mechanisms for economic decision-making with @AnnDuan2 and @SWC_Neuro!

Pls RT👉 We are hiring! My lab @BrandeisNeuro has an opening for a Research Tech. It is an ideal position for a recent college grad passionate about uncovering how the brain learns within a young and collaborative team. More info at https://t.co/zskCLSrwOs or DM me.

🚨 We’re hiring 🚨 Interested in glial biology, retina ageing and killifish? We will soon be advertising a postdoc and technician position in my laboratory. Please get in touch if interested. Picture of our new glial reporter transgenic killifish. Courtesy of @ChiKuoHimself

Come join our amazing department! I started on the fellowship route - it's a great way to begin your independent lab. Reach out if you have any qs!

'Mini analysis' is an unreliable reporter of synaptic changes https://t.co/k7PIB37OKO #biorxiv_neursci