Michael Birnbaum
@MEBirnbaum
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Immune Engineer. @MITdeptofBE @kochinstitute @ragoninstitute
Joined December 2009
My department (MIT Biological Engineering) is hiring at the Assistant Professor level! We are looking for someone in immunology/immunotherapy/immune engineering, broadly defined.
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Welcome to the team!!.
I’m beyond thrilled to share that I will be joining the @MIT Department of Biological Engineering @MITdeptofBE as an Assistant Professor in January 2026! I will also be an intramural member of the legendary Koch Institute for Integrative Cancer Research at MIT @kochinstitute
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RT @KeloniaTx: Our Director, Discovery Research, Russell McConnell, will be at @ASGCTherapy to discuss preclinical data that supports the p….
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One year into our TCR-based challenge, I can say already that leading a #CancerGrandchallenges team may the most scientifically rewarding thing I have done. Amazing way to do impactful, international research on very hard problems!.
📢 Announcing 7 new #CancerGrandChallenges 📢. We're thrilled to announce 7 new challenges, now open for Expressions of Interest from global, interdisciplinary teams. Awards of up to £20m ($25m) are available. Discover the new challenges:
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RT @sixian_you: Deeper and noninvasive metabolic imaging powered by multimode fiber sources by Kunzan Liu, Tong Qiu, Honghao Cao. Awesome….
news.mit.edu
MIT researchers developed a non-invasive imaging technique that enables laser light to penetrate deeper into living tissue, capturing sharper images of cells. This could help clinical biologists...
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RT @TheMarkFdn: We’re in Boston for the 1st annual meeting of the @CancerGrand Challenges MATCHMAKERS team! The team, which we sponsor with….
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RT @GabriCorso: Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy o….
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RT @CancerGrand: Congratulations David Baker (@UW, member of #CancerGrandChallenges team MATCHMAKERS), who's won the 2024 Nobel Prize in Ch….
cancergrandchallenges.org
Meet MATCHMAKERS, whose challenge is to decipher the T-cell receptor cancer-recognition code.
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RT @MEBirnbaum: My department (MIT Biological Engineering) is hiring at the Assistant Professor level! We are looking for someone in immuno….
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Engineering background not strictly necessary (after all, they hired me!) so long as you are quantitative/building tools/goal-oriented. MIT is truly a special place to work - please spread the word as we look for someone to join us.
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RT @vcluca1: I am excited to share our @NatureComms paper describing the structure of #LAG3 bound to MHC-II. This project was carried out b….
nature.com
Nature Communications - Lymphocyte activation gene-3 (LAG3) is an immune checkpoint protein recently approved as a target for anti-melanoma therapy. Here, the authors solve the structure of mouse...
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RT @biorxiv_immuno: Library-based single-cell analysis of CAR signaling reveals drivers of in vivo persistence #bi….
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Very proud of this work by @calebrperez! Elegantly combining elements of CAR screening and single cell genomics to give insight into how CAR composition affects T cell functional state, with a lot to learn about how to design CARs and the diversity possible for T cell function.
Excited to share some of my PhD work was pre-printed! Using single-cell sequencing, we took a deep look at a library of CAR signaling architectures to try to identify signal-intrinsic drivers of CAR-T function🧵👇 @MEBirnbaum @kochinstitute @MITdeptofBE.
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RT @tjburns08: Flow/CyTOF users and leaders: here is an interface that allows you to see exactly where a given cell on a biaxial plot is on….
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What a ride to be leading this effort to solve T cell recognition - incredible opportunity and team, and 5 years to throw everything we have at it. Thanks @CancerGrand @theNCI @TheMarkFdn for the award - and @kochinstitute @MITdeptofBE @ragoninstitute for the continual support.
The second winning @CancerGrand team featured at the #CancerGrandChallenges Summit is Team MATCHMAKERS (T-Cell Receptors challenge) led by @MEBirnbaum (@MITdeptofBE) - congratulations!
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RT @DanielWhiteson: I will keep maxing out these nonsense categories until grad programs phase them out.
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RT @biorxiv_immuno: Two-dose "extended priming" immunization amplifies humoral immune responses by synchronizing vaccine delivery with the….
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RT @KlebanoffLab: 🚨🧬💉Everything you wanted to know about TCR therapies* (*but were afraid to ask). Check out our new review in @NatRevDrugD….
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