LUCKY when one can combine work with friendship. I am very lucky @ucsfhealth w. friends @immunox @UCSFAging & friendly relationships with @UCSF leadership. Excited how this "group of friends" imagined a 2017 dream & very grateful to Bakar family and others to make this reality.

Early in the pandemic, kids were hospitalized with a mysterious disease, MIS-C. A team led by @DrAaron14 @MAndersonUCSF @czbiohub discovered how mild COVID led to MIS-C, hinting at what might go wrong in autoimmune diseases like #MS. @BCH_InTheNews @stjude https://t.co/MNJTXkhd37

Scientists Get to the Bottom of COVID’s Worst Pediatric Complication

Proud of our team that unlocked this terrible complication of COVID-19 in children. @AtUcsf @UCSF @immunox https://t.co/cDBFrRYvLh

Congrats to our team in the UCSF Diabetes Center!

Insights: @DrCindyMa & @stutangye discuss new study from @MACattackLab ( https://t.co/4LLX8joriS) that proposes a role for dysregulated IL-22 production by Th17 cells in causing some aspects of immune-mediated skin inflammation in #STAT3GOF syndrome. https://t.co/oFtMQJ4cjs

Great piece on all of the excitement around Ozempic and GLP-1 agonists. Great job Suneil!

Honored and thrilled for this recognition

Excited to share new collaborative work on the autoreactome that just came out in JCI https://t.co/4wJsiWVhZe

"Decoding gene regulation with CRISPR perturbations" by @McManus_Lab postdoc Stefan Oberlin published in @NatureBiotech

Excited to share some new collaborative work with the Kappler lab on how thymic tolerance to insulin is maintained in a model of T1 Diabetes. Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones | PNAS

Excited to be part of a team that identified a rare family with a defect in PDL1 that has a strong link to type 1 diabetes and other immune dysregulation.

Finalize & Submit your abstract ahead of time ✔️ There's only 3 days remaining to submit your research and be a part of the FOCIS 2024 Annual Meeting! Don't wait - submit today ⏳: https://t.co/m2pdB6hPDI

Congrats to Mianmian and Tony on this important collaborative work on thymic selection of autoreactive T cells! Tracking the role of Aire in immune tolerance to the eye with a TCR transgenic mouse model | PNAS

New in @Nature: #COVID patients with specific mutations in NFKB2 gene develop antibodies to type I interferons, which are associated with a severe disease course, often involving hospitalization and ICU care. 🧵 1/5

Congrats to Elze and our team that have developed a new powerful tool to assess the specificity of autoimmunity in mouse models. @AtUcsf @immunox @UCSF https://t.co/n47EokLTye

Ready for a masterpiece! Jointly led by Drs. @anne_puel, Jean-Laurent Casanova (@casanova_lab), @MAndersonUCSF, and Luigi Notarangelo, this @Nature study talks about autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency. https://t.co/4xMgv7euVA

Congrats to @Tang_Lab_UCSF Postdoc Roberto Castro Gutierrez for being named a 2024 @CIRMnews Scholar

Excited to share new collaborative work in Nature on the genetic underpinnings of COVID susceptibility that is linked to a defect in the thymus. Great thanks to my colleagues in the Casanova, Puel, and DeRisi labs! @AtUcsf @immunox @UCSF https://t.co/GYbe6zBk4j

Congrats to the Waterfield lab on this newly identified regulator of thymic tolerance.@AtUcsf @UCSF Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance | Science Immunology