
French Reference Center for PNS and AE
@LyonPNS_AE
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International neurologists and scientifics for a better diagnosis/treatment for patients with #Autoimmune #Encephalitis and PNS #Cancer #immunology #neurology
Lyon
Joined September 2020
Time to present our team starting with Pr Jérôme Honnorat, who works on PNS and AE for more than 25 years. He is head of the neurooncology department of Lyon’s hospital and director of the French rare disease. #Neurooncologist #autoimmune #encephalitis
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RT @Mayo_AING: My lab is looking for an antibody engineer-protein biochemist to study ~500 patient derived monoclonal antibodies. Towards n….
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RT @carstenfinke: Our new study on @Brain1878 on atrophy patterns in IgLON5 disease led by the faboulous @SelinaYogeshwar.
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💥 Immune checkpoint inhibitors can trigger or worsen paraneoplastic neurologic syndromes. This study focuses on CV2/CRMP5-PNS patients treated with ICIs & compares outcomes with ICI-naïve cases. 📖 Read more 👉 #NeuroOncology #PNS #NeuroTwitter #ICI.
neurology.org
Background and ObjectivesImmune checkpoint inhibitors (ICIs) are oncologic treatments that may trigger or worsen paraneoplastic neurologic syndromes (PNSs). This study describes patients with...
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🔬 New study: .🧠 κ-FLC index can’t differentiate MS from GFAP astrocytopathy. 🔍 But λ-FLC index shows potential as a diagnostic & prognostic biomarker in GFAP. 🧪 Higher λ-FLC levels linked to worse outcomes. #NeuroTwitter #MS #GFAP #Biomarkers.
pubmed.ncbi.nlm.nih.gov
The κ-FLC index alone cannot distinguish between autoimmune GFAP astrocytopathy and MS. We indicate a potential diagnostic and prognostic role of the λ-FLC index in GFAP astrocytopathy that needs...
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📢 Registrations are open!. Join us in Lyon on Sept 18–19, 2025, for the congress on Autoimmune Encephalitis & Paraneoplastic Syndromes, under the presidency of Pr. Jérôme Honnorat. Program & registrations here: #neuroimmunology #autoimmuneencephalitis
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⚠️ Up to 1 in 4 patients with anti-NMDAR encephalitis relapse during recovery! 🧠 This study dives into why, who’s at risk, and how immunotherapy may help. 💉🔍 #NeuroTwitter #Encephalitis #BrainHealth.@lundahl1 @Vogrig_Alberto.
neurology.org
Background and ObjectivesDuring the recovery phase of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis, up to 25% of relapses have been reported. Herein, we aimed to clinically characterize...
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🧠 Autoimmune GFAP astrocytopathy: a large French cohort study (116 patients) reveals varied clinical presentations & long-term outcomes. Relapses were common but disability remained low in most cases. 🔗 #Neuroimmunology #AutoimmuneEncephalitis #Neurology.
pubmed.ncbi.nlm.nih.gov
This study suggests a greater impact than previously described in long-term outcomes of patients with GFAP astrocytopathy and reports concomitant tumor at presentation as a risk factor for relapse.
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🧠 SAVE THE DATE.📅 Sept 18–19, 2025 | 📍Lyon, France.Congress on Autoimmune Encephalitis & Paraneoplastic Syndromes, chaired by Prof. Jérôme Honnorat. Program & registration coming soon!.#Neurology #Immunology #Oncology #AutoimmuneEncephalitis #SaveTheDate
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RT @neurochecklists: Anti-IgLON5 Disease 10 Years Later.What We Know and What We Do Not Know.
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RT @DiLibertoMD: Thanks to all the coauthors @Mayo_AING @Vogrig_Alberto @LyonPNS_AE @Div_Dubey @merkler_lab @neuroimmuclinic @BogdanDragan….
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RT @MichelleSaidel: Mayo Clinic is hosting a conference on auto immune encephalitis in May. Important topic!.
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RT @andreuvilaseca7: Clinical trials in #AutoimmuneEncephalitis are ongoing!.Basket trial designs help tackle rarity & heterogeneity, but p….
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RT @Mayo_AING: Correct re clinical differences. There are a few distinguishing imaging features too:.Most AE is very focal within medial te….
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RT @StaceyLClardy: Prof. Dalmau @idibaps @PennNeurology @GreenJournal speaking on the progress made over the past decade of Neurology: Neur….
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RT @Vogrig_Alberto: Exciting session on autoimmune neurology #AANAM2025 — @DiLibertoMD discussed the role of pSTAT1 in the synaptic patholo….
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🎉 Thank you for the 10 years of collaboration & the 10th annual Brain Team Filière Day! A decade of progress, partnerships, and innovation in neurology and rare diseases—let’s make this milestone unforgettable! 🧠✨ #BrainTeam10Years #NeuroCollaboration.@BRAINTEAM_FSMR
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🚨 New study! ICS score tracks severity&predicts mortality in #IgLON5. Bulbar ICS at diagnosis is key to identifying high-risk patients, highlighting the need for early recognition& management of bulbar dysfunction. 🔗 @maccuve @luciacamp7 @Vogrig_Alberto.
link.springer.com
Journal of Neurology - Anti-IgLON5 disease presents with diverse symptoms, whose severity can be measured by the anti-IgLON5 disease composite score (ICS). This study applied the ICS to a...
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