A/Prof Luke Hesson
@LukeHesson
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Geneticist | Cancer Researcher | Father of 3 fellow nerds | Fellow of the Faculty of Science, Royal College of Pathologists | Amateur artist
Sydney, New South Wales
Joined March 2014
This mind blowing video (and @ProfBrianCox soothingly authoritative narration) explains just how vast our universe is
bbc.co.uk
Join Professor Brian Cox on an astonishing journey from Earth to the edge of the known Universe.
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Our pre-print describing the @uk_biobank Pharma Proteomics Project (UKB-PPP) is now online! https://t.co/ymJuXDw9sg We identify 10k+ genetic associations w/ protein concentrations; 85% are new. The data should help drive discovery of new biomarkers, diagnostics & medicines.
biorxiv.org
The UK Biobank Pharma Proteomics Project (UKB-PPP) is a collaboration between the UK Biobank (UKB) and thirteen biopharmaceutical companies characterising the plasma proteomic profiles of 54,306 UKB...
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I'm completing 3,139 push-ups in 24 days to raise awareness and funds for mental health. Please support me as I #pushforbetter in June.
thepushupchallenge.com.au
3,214 push-ups in 23 days. 4-26 June 2025. Level up your physical and mental fitness while making a difference to the mental health of all Australians.
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#leavingacademia If this is something you’re considering then read this first https://t.co/cYx0XiWA1c
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We’re on the lookout for an experienced Senior Scientist to help with the development of a new tumour sequencing service at Douglass Hanly Moir Pathology. https://t.co/xrk1jNgsIi This is a very rare opportunity for a senior role in a large, busy genetic testing lab
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Wondering what the story behind the #ovariestalkaboutthem campaign is?Want to watch a video where I talk a lot WITH MY HANDS?! 🤦🏼♀️ Ignore my hand waving and listen to my message about being motivated by all the women and families affected by #ovariancancer
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Ovaries. Talk about them. Our campaign with @camillaandmarc launches today to raise awareness and funding for #OvarianCancer Find out more at https://t.co/2isxIqt5jK
#ovariestalkaboutthem
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Global temperature anomalies between the years 1880-2021. Source @NASA Amazing data visualisation, so clear!
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Sadly, this is a story that is all too common in Australia 2022. Australia spent a million dollars training me – and now I’m leaving
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I love a good pathway diagram and this one’s a cracker! Nice work @chloebrodgers @PeterAJohansson @NBroit and @antoniagage
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In this article I describe some of the scenarios in which epigenetic testing may have clinical utility and consider some of the challenges that must be overcome for epigenetic testing to become more mainstream in genetic pathology #genetic #pathology #epigenetics #clinical
Check the new hot topic article published in the #EFLM Newsletter! 📖 https://t.co/H82EztDLlx, pp. 5-6. 📰 "The clinical utility of #epigenetic testing in laboratory medicine" by @LukeHesson🔬
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Very happy to finally see our work on DNA mismatch repair deficiency out in print. We showed that MSH2/MSH6 ≠ MLH1/PMS2 loss when it comes to mutational signatures in cancer patients. @ScienceAdvances
https://t.co/EZv51KBiwY Link to the old twittorial: https://t.co/txlDhEMqhg.
science.org
DNA mismatch repair is essential for protecting the human genome from damage induced by 5-methylcytosine deamination.
Excited to share our latest preprint titled "Deficiency in DNA mismatch repair of methylation damage is a major mutational process in cancer" https://t.co/MjZLhn3qnf
#Cancer #DNARepair
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Summer scholarships are now open at the Garvan Institute of Medical Research for undergraduates studying computer science, biology, bioinformatics, maths, stats or engineering. Apply here: https://t.co/6h9KB9cuEq
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My son has perfected the art of snuffing out birthday candles in a COVID friendly way!
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While I didn’t leave science I did leave academia and here’s why
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Beware survivorship bias. For objective careers advice, talk to those who left science or academia as well as those who stayed. Great advice for mentors and mentees in a new Nature opinion piece
nature.com
Nature - For objective careers advice, talk to those who left science as well as those who stayed.
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In today’s issue of @ScienceMagazine, Dr Daniel MacArthur reviews how new approaches enabling scientists to uncover the impact of variants on biological function will transform disease diagnosis, risk prediction, and the development of new therapies: https://t.co/Tc7iqe1my4
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Congratulations @qianthefirst and team on a really interesting paper
I’m excited to share our latest publication on the importance of #DNAmethylation in maintenance of DNA replication timing and 3D genome organization. Out in @CellReports today! @ClarkEpiLab @GarvanInstitute @suscla1
#epigenetics #3Dgenome
https://t.co/Ev00kauc0E
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