Larisa Labzin
@LarisaLabzin
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Leader of the viruses and innate immunity group @IMBatUQ. We love studying innate sensing pathways and acute respiratory viruses. Opinions my own.
Brisbane, Queensland
Joined November 2012
Postdoc position in dendritic cell and cross-presentation biology - four days left to apply: https://t.co/WjBuXT7KIQ Join our team to work on these coolest cells ever! š„°
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Iām very proud of my postdoc Helen Mostafavi who just gave a great talk on endothelial dysfunction in SARS-Cov-2 @options2024. Itās been a great collaboration with @VesselDynamics and @KengYih and @K_RenfreeShort
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I'm very proud to have co-authored this review on antibodies and infection with my twitterless PhD student Tyron Esposito, @TheWellsLab and @HendersonLab. Please check it out š Mechanisms of antibody-dependent enhancement of infectious disease | Nature Reviews Immunology
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Interested in Caspase and LPS signalling? Looking for a multidisciplinary position with a bit of immunology, biochemistry and host-pathogen interactions? Look no further! Our lab is recruiting a second PDRA funded by @BBSRC. See details below
#JobAlert @dave_boucher is seeking a postdoc in innate immunity, to perform lab-based research on non-canonical inflammasomes function in human cells in response to bacterial infections #immunity #infection #lab Deadline: 13/08/24 Read more and apply:
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Hi everyone! Iām on the lookout for a new role and would really appreciate your support. I'm particularly interested in chatting with #pharma, #biotech and #CROs about how my #biomedical #research skills may benefit your team. I am based in Brisbane, Australia.
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Highly recommend Rinie!
If you hear of any exciting opportunities or are open to chatting, please send me a DM or reply below! #OpenToWork #Brisbane #Australia
https://t.co/axebY2ONnb
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Howās your abstract looking for OptionsXII? April 5th coming upā¦Join the School of Influenza before the main conference kickoff to become FLU-ENT in all things Flu related
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Options 2024! Are you ready! Submit your abstract by April 5th in these categories https://t.co/Wqj1dcEFd7 so you can visit this amazing place⦠Brisbane https://t.co/oLxzVJPqR4 or sneak off to https://t.co/7Eg70jEIEU Amidst amazing research in flu, COVID and RSV
queensland.com
Discover the best things to do in Brisbane - from city highlights and free activities to rooftop bars, island escapes, family fun and wild outdoor adventures. Your sunshine-filled Brisbane getaway...
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PhD projects available now for a 2024 START. Studying virus: host interactions working on African swine fever virus or Japanese encephalitis using novel tools( inc. multiomics and ex vivo models ) to understand pathogenesis with impact @CSIRO Job link in comments
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It's finally out! Well-done to @amy_chancan and many others from @inflammasomelab! Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme
life-science-alliance.org
The noncanonical inflammasome is a signalling complex critical for cell defence against cytosolic Gram-negative bacteria. A key step in the human noncanonical inflammasome pathway involves unleashing...
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Many extraordinary, life changing inventions have come from š¦šŗ From the bionic ear to wifi. But they won't keep happening if we don't fund research. Federal research investment has ā¬ļø to record lows. This budget is an opportunity to change that. https://t.co/RKrGFnbp3i
canberratimes.com.au
Government spending on research has dropped to its lowest on record, triggering a warning from universities. New forecasts...
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Extremely happy to share our latest publication. Another fantastic study from the outstanding Dr @katebalka! What a PhD from this superstar! @MonashBDI @embojournal Enjoy!š Termination of STING responses is mediated via ESCRTādependent degradation
link.springer.com
The EMBO Journal - cGASāSTING signalling is induced by detection of foreign or mislocalised host doubleāstranded (ds)DNA within the cytosol. STING acts as the major signalling hub,...
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A big shoutout to the @IMBatUQ imaging and microscopy experts @Lagendijk_lab @VesselDynamics @LabParton @JamesRa91582693 because seeing is believing. And of course to @SarahLondrigan and @inflammasomelab for their outstanding leadership and support.
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Huge thanks to all of the people who contributed to this project including my fantastic (twitterless) lab Xiaohui Wang and Tyron Esposito and Kathrin Eschke, and @KengYih @claudiajades @brittanyhill__ @CarolineLHolley @S_Emming @FritzlarSvenja @nefzgerc @K_RenfreeShort
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Our study sheds light on how our favourite innate immune sentinel cells trigger inflammation and control virus infections.
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We think all of those ACE2-neg macrophages will instead respond to neighbouring infected cells ā like @katbarnett3, @ting_lab_unc found in COVID-19 https://t.co/zo4Ox6ssVn,
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These ACE2-pos macs CAN make new infectious virions, BUT, all those anti-viral cytokines the macs make stop new virion release. If we block cytokine induction with a TBK1 inhibitor (BX795) then we rescue ACE2-pos mac virus production.
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But SARS-CoV-2 can enter ACE2-pos macs (maybe even fuse at the plasma membrane) AND trigger macrophage cytokine release.
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